PRUNETIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H12O5
Molecular Weight	284.2635
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC2=C(C(=O)C(=CO2)C3=CC=C(O)C=C3)C(O)=C1

InChI

InChIKey=KQMVAGISDHMXJJ-UHFFFAOYSA-N

InChI=1S/C16H12O5/c1-20-11-6-13(18)15-14(7-11)21-8-12(16(15)19)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
In vitro antioxidant activity of some selected Prunus species in Korea.	2002 Dec	12510840
Identification of CYP1A2 as the main isoform for the phase I hydroxylated metabolism of genistein and a prodrug converting enzyme of methylated isoflavones.	2003 Jul	12814970
Immunoassay for biochanin A.	2004 Nov	15604024
Dalsympathetin--a new isoflavone gentiobioside from Dalbergia sympathetica (Dennst.).	2006 Feb	16319013
Determination of isoflavones in dietary supplements containing soy, Red Clover and kudzu: extraction followed by basic or acid hydrolysis.	2006 Feb 24	16413562
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	2006 Nov	16497524
Cytotoxic constituents from Butea superba Roxb.	2007 Jan 19	16973318
Structure of daidzin, a naturally occurring anti-alcohol-addiction agent, in complex with human mitochondrial aldehyde dehydrogenase.	2008 Aug 14	18613661
Flavonoid-responsive nodY-lacZ expression in three phylogenetically different Bradyrhizobium groups.	2008 May	18449225
Disposition of flavonoids via enteric recycling: UDP-glucuronosyltransferase (UGT) 1As deficiency in Gunn rats is compensated by increases in UGT2Bs activities.	2009 Jun	19264971
Structure and concentration changes affect characterization of UGT isoform-specific metabolism of isoflavones.	2009 Sep-Oct	19545173
The influence of bovine milk high or low in isoflavones on hepatic gene expression in mice.	2010	20652050
Electrospray ionization Fourier transform ion cyclotron resonance mass spectrometric and semi-empirical calculations study of five isoflavone aglycones.	2010 Dec 15	21072799
Secondary metabolites and antimycobacterial activities from the roots of Ficus nervosa.	2010 Jul	20658670
Flavonoids activate pregnane x receptor-mediated CYP3A4 gene expression by inhibiting cyclin-dependent kinases in HepG2 liver carcinoma cells.	2010 Jun 16	20553580
Isoflavones isolated from red clover (Trifolium pratense) inhibit smooth muscle contraction of the isolated rat prostate gland.	2010 Sep	20638256
Anti-inflammatory effect of prunetin via the suppression of NF-κB pathway.	2013 Aug	23597450

Patents

Name

Type

Language

PRUNETIN

Common Name

English

4',5-DIHYDROXY-7-METHOXYISOFLAVONE

Common Name

English

5-HYDROXY-3-(4-HYDROXYPHENYL)-7-METHOXY-4H-1-BENZOPYRAN-4-ONE

Systematic Name

English

PRUNETIN [MI]

Common Name

English

PRUNUSETIN

Common Name

English

Code System Code Type Description

CHEBI

8600