Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C9H18NO8P |
| Molecular Weight | 299.2149 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)(COP(O)(O)=O)[C@@H](O)C(=O)NCCC(O)=O
InChI
InChIKey=XHFVGHPGDLDEQO-ZETCQYMHSA-N
InChI=1S/C9H18NO8P/c1-9(2,5-18-19(15,16)17)7(13)8(14)10-4-3-6(11)12/h7,13H,3-5H2,1-2H3,(H,10,14)(H,11,12)(H2,15,16,17)/t7-/m0/s1
Phosphopantothenic acid is an amidoalkyl phosphate that is the 4-phosphate derivative of (R)-pantothenic acid. Phosphopantothenic acid is not permeable to cell membranes due to its anionic character, consistent with the observation that systemic administration of Phosphopantothenic acid does not restore CoA levels in cellular and mouse models
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Chemo- and regioselective peptide cyclization triggered by the N-terminal fatty acid chain length: the recombinant cyclase of the calcium-dependent antibiotic from Streptomyces coelicolor. | 2004 Mar 16 |
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| Mycobacterium tuberculosis pantothenate kinase: possible changes in location of ligands during enzyme action. | 2009 Apr |
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| Kinetic characterization of human phosphopantothenoylcysteine synthetase. | 2009 Dec |
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| Characterization and kinetics of phosphopantothenoylcysteine synthetase from Enterococcus faecalis. | 2009 Mar 31 |
|
| Selective inhibitors of bacterial phosphopantothenoylcysteine synthetase. | 2009 Nov 18 |
|
| Kinetic and inhibition studies of dihydroxybenzoate-AMP ligase from Escherichia coli. | 2010 May 4 |
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FDA ORPHAN DRUG |
427114
Created by
admin on Sat Dec 16 09:27:39 GMT 2023 , Edited by admin on Sat Dec 16 09:27:39 GMT 2023
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5875-50-3
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DTXSID40974271
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1SCE5NG3E8
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15905
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41635
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admin on Sat Dec 16 09:27:39 GMT 2023 , Edited by admin on Sat Dec 16 09:27:39 GMT 2023
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ACTIVE MOIETY
