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Details

Stereochemistry ABSOLUTE
Molecular Formula C20H28O10
Molecular Weight 428.4303
Optical Activity UNSPECIFIED
Defined Stereocenters 9 / 9
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of ROSAVIN

SMILES

O[C@H]1CO[C@@H](OC[C@H]2O[C@@H](OC\C=C\C3=CC=CC=C3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H]1O

InChI

InChIKey=RINHYCZCUGCZAJ-IPXOVKFZSA-N
InChI=1S/C20H28O10/c21-12-9-28-19(17(25)14(12)22)29-10-13-15(23)16(24)18(26)20(30-13)27-8-4-7-11-5-2-1-3-6-11/h1-7,12-26H,8-10H2/b7-4+/t12-,13+,14-,15+,16-,17+,18+,19-,20+/m0/s1

HIDE SMILES / InChI

Description

Rosavin is a glycoside found in the plant Rhodiola rosea. It is a component of rosavin capsules from Ameriden which are marketd to reduce stress and anxiety.

Approval Year

Unknown
139594
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Not Provided
504
Unknown

Approved Use

Unknown
Palliative
Not Provided
504
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Examining the genomic influence of skin antioxidants in vitro.
2010

Sample Use Guides

In Vivo Use Guide
For Adults‚ as a dietary supplement‚ take 1 capsule in the morning and 1 capsule in the early afternoon.
Route of Administration: Oral
In Vitro Use Guide
Curator's Comment: It was examined the potential rosavin to alter cell growth of human Jurkat T cells, apoptosis of splenic mouse CD3 T cells and expression of the surface markers and phosphorylation of extracellular signal-regulated kinase (ERK). The initial screening for cell viability in Jurkat T cells and for apoptosis of mouse T cells showed the strongest activity for rosavin. Rosavin did not alter significantly the dynamic of CD69 expression upon stimulation, but altered TNF-related apoptosis-inducing ligand (TRAIL) expression. Rosavin inhibited TRAIL up-regulation.
Unknown
Name Type Language
ROSAVIN
USP-RS  
Common Name English
ROSAVIN (CONSTITUENT OF RHODIOLA ROSEA) [DSC]
Common Name English
ROSAVIDIN
Common Name English
.BETA.-D-GLUCOPYRANOSIDE, (2E)-3-PHENYL-2-PROPENYL 6-O-.ALPHA.-L-ARABINOPYRANOSYL-
Systematic Name English
.BETA.-D-GLUCOPYRANOSIDE, (2E)-3-PHENYL-2-PROPEN-1-YL 6-O-.ALPHA.-L-ARABINOPYRANOSYL-
Systematic Name English
ROSAVIN, (-)-
Common Name English
ROSAVIN [USP-RS]
Common Name English
(-)-ROSAVIN
Common Name English
.BETA.-D-GLUCOPYRANOSIDE, 3-PHENYL-2-PROPENYL 6-O-.ALPHA.-L-ARABINOPYRANOSYL-, (E)-
Systematic Name English
Classification Tree Code System Code
DSLD 2389 (Number of products:23)
Created by admin on Sat Dec 16 09:51:47 GMT 2023 , Edited by admin on Sat Dec 16 09:51:47 GMT 2023
Code System Code Type Description
PUBCHEM
9823887
Created by admin on Sat Dec 16 09:51:47 GMT 2023 , Edited by admin on Sat Dec 16 09:51:47 GMT 2023
PRIMARY
WIKIPEDIA
Rosavin
Created by admin on Sat Dec 16 09:51:47 GMT 2023 , Edited by admin on Sat Dec 16 09:51:47 GMT 2023
PRIMARY
FDA UNII
1R72C0ROME
Created by admin on Sat Dec 16 09:51:47 GMT 2023 , Edited by admin on Sat Dec 16 09:51:47 GMT 2023
PRIMARY
RS_ITEM_NUM
1605588
Created by admin on Sat Dec 16 09:51:47 GMT 2023 , Edited by admin on Sat Dec 16 09:51:47 GMT 2023
PRIMARY
EPA CompTox
DTXSID101027577
Created by admin on Sat Dec 16 09:51:47 GMT 2023 , Edited by admin on Sat Dec 16 09:51:47 GMT 2023
PRIMARY
CAS
84954-92-7
Created by admin on Sat Dec 16 09:51:47 GMT 2023 , Edited by admin on Sat Dec 16 09:51:47 GMT 2023
PRIMARY
SUBSTANCE RECORD
Structure of ROSAVIN
NIH
NCATS
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