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Details

Stereochemistry ACHIRAL
Molecular Formula C20H15N9O
Molecular Weight 397.3928
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LAS-191954

SMILES

C[C@H](NC1=NC=NC(N)=C1C#N)C2=NN3C=CC(C#N)=C3C(=O)N2C4=CC=CC=C4

InChI

InChIKey=QUMWKKVIZAIAHU-LBPRGKRZSA-N
InChI=1S/C20H15N9O/c1-12(26-18-15(10-22)17(23)24-11-25-18)19-27-28-8-7-13(9-21)16(28)20(30)29(19)14-5-3-2-4-6-14/h2-8,11-12H,1H3,(H3,23,24,25,26)/t12-/m0/s1

HIDE SMILES / InChI

Approval Year

Name Type Language
LAS-191954
Common Name English
PYRROLO(2,1-F)(1,2,4)TRIAZINE-5-CARBONITRILE, 2-((1S)-1-((6-AMINO-5-CYANO-4-PYRIMIDINYL)AMINO)ETHYL)-3,4-DIHYDRO-4-OXO-3-PHENYL-
Systematic Name English
LAS191954
Code English
2-((1S)-1-((6-AMINO-5-CYANO-4-PYRIMIDINYL)AMINO)ETHYL)-3,4-DIHYDRO-4-OXO-3-PHENYLPYRROLO(2,1-F)(1,2,4)TRIAZINE-5-CARBONITRILE
Systematic Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 548916
Created by admin on Sat Dec 16 01:46:07 GMT 2023 , Edited by admin on Sat Dec 16 01:46:07 GMT 2023
FDA ORPHAN DRUG 444614
Created by admin on Sat Dec 16 01:46:07 GMT 2023 , Edited by admin on Sat Dec 16 01:46:07 GMT 2023
Code System Code Type Description
FDA UNII
1MK0TQ597B
Created by admin on Sat Dec 16 01:46:07 GMT 2023 , Edited by admin on Sat Dec 16 01:46:07 GMT 2023
PRIMARY
CAS
1403947-26-1
Created by admin on Sat Dec 16 01:46:07 GMT 2023 , Edited by admin on Sat Dec 16 01:46:07 GMT 2023
PRIMARY
SMS_ID
100000183853
Created by admin on Sat Dec 16 01:46:07 GMT 2023 , Edited by admin on Sat Dec 16 01:46:07 GMT 2023
PRIMARY
EU-Orphan Drug
EU/3/14/1335(POSITIVE)
Created by admin on Sat Dec 16 01:46:07 GMT 2023 , Edited by admin on Sat Dec 16 01:46:07 GMT 2023
PRIMARY On 15 October 2014, orphan designation (EU/3/14/1335) was granted by the European Commission to Almirall S.A., Spain, for (S)-2-(1-((6-amino-5-cyanopyrimidin-4-yl)amino)ethyl)-4-oxo-3-phenyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazine-5-carbonitrile for the treatment of pemphigus.
PUBCHEM
70675172
Created by admin on Sat Dec 16 01:46:07 GMT 2023 , Edited by admin on Sat Dec 16 01:46:07 GMT 2023
PRIMARY