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Details

Stereochemistry ACHIRAL
Molecular Formula C5H9N3
Molecular Weight 111.1451
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BETAZOLE

SMILES

NCCC1=NNC=C1

InChI

InChIKey=JXDFEQONERDKSS-UHFFFAOYSA-N
InChI=1S/C5H9N3/c6-3-1-5-2-4-7-8-5/h2,4H,1,3,6H2,(H,7,8)

HIDE SMILES / InChI

Description

BETAZOLE is a histamine H2 receptor agonist used clinically to test gastric secretory function.

Approval Year

1954
117
Targets

Targets

Primary TargetPharmacologyConditionPotency
Agonist
2678
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
Approved
8429
Histalog

Approved Use

For use clinically to test gastric secretory function.

Launch Date

-5.36457609E11
Overview

Overview

CYP3A4CYP2C9CYP2D6hERG

OverviewOther

Other InhibitorOther SubstrateOther Inducer
ALDH
8
Drug as perpetrator​

Drug as perpetrator​

TargetModalityActivityMetaboliteClinical evidence
ALDH
8
 yes
Sourcing

Sourcing

Vendor/AggregatorIDURL
ChEBI
CHEBI:59170
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:59170
MolPort
MolPort-001-787-387
https://www.molport.com/shop/molecule-link/MolPort-001-787-387
MolPort
MolPort-006-167-503
https://www.molport.com/shop/molecule-link/MolPort-006-167-503
ZINC
ZINC000000001028
http://zinc15.docking.org/substances/ZINC000000001028
eMolecules
31503597
https://www.emolecules.com/cgi-bin/more?vid=31503597
eMolecules
34962
https://www.emolecules.com/cgi-bin/more?vid=34962
PubMed

PubMed

TitleDatePubMed
Gastric secretory and hormonal patterns in end-stage chagasic achalasia.
2009
Name Type Language
BETAZOLE
INN   MI   VANDF   WHO-DD  
INN  
Official Name English
Betazole [WHO-DD]
Common Name English
1H-PYRAZOLE-3-ETHANAMINE
Systematic Name English
BETAZOLE [VANDF]
Common Name English
2-(1H-PYRAZOL-3-YL)ETHANAMINE
Systematic Name English
AMETAZOLE
Common Name English
betazole [INN]
Common Name English
BETAZOLE [MI]
Common Name English
3-(2-AMINOETHYL)PYRAZOLE
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C1937
Created by admin on Fri Dec 15 15:05:25 UTC 2023 , Edited by admin on Fri Dec 15 15:05:25 UTC 2023
WHO-VATC QV04CG02
Created by admin on Fri Dec 15 15:05:25 UTC 2023 , Edited by admin on Fri Dec 15 15:05:25 UTC 2023
WHO-ATC V04CG02
Created by admin on Fri Dec 15 15:05:25 UTC 2023 , Edited by admin on Fri Dec 15 15:05:25 UTC 2023
Code System Code Type Description
SMS_ID
100000085852
Created by admin on Fri Dec 15 15:05:25 UTC 2023 , Edited by admin on Fri Dec 15 15:05:25 UTC 2023
PRIMARY
WIKIPEDIA
BETAZOLE
Created by admin on Fri Dec 15 15:05:25 UTC 2023 , Edited by admin on Fri Dec 15 15:05:25 UTC 2023
PRIMARY
EVMPD
SUB05805MIG
Created by admin on Fri Dec 15 15:05:25 UTC 2023 , Edited by admin on Fri Dec 15 15:05:25 UTC 2023
PRIMARY
INN
574
Created by admin on Fri Dec 15 15:05:25 UTC 2023 , Edited by admin on Fri Dec 15 15:05:25 UTC 2023
PRIMARY
IUPHAR
7126
Created by admin on Fri Dec 15 15:05:25 UTC 2023 , Edited by admin on Fri Dec 15 15:05:25 UTC 2023
PRIMARY
MERCK INDEX
m2455
Created by admin on Fri Dec 15 15:05:25 UTC 2023 , Edited by admin on Fri Dec 15 15:05:25 UTC 2023
PRIMARY Merck Index
DRUG CENTRAL
357
Created by admin on Fri Dec 15 15:05:25 UTC 2023 , Edited by admin on Fri Dec 15 15:05:25 UTC 2023
PRIMARY
CAS
105-20-4
Created by admin on Fri Dec 15 15:05:25 UTC 2023 , Edited by admin on Fri Dec 15 15:05:25 UTC 2023
PRIMARY
DRUG BANK
DB00272
Created by admin on Fri Dec 15 15:05:25 UTC 2023 , Edited by admin on Fri Dec 15 15:05:25 UTC 2023
PRIMARY
FDA UNII
1C065P542O
Created by admin on Fri Dec 15 15:05:25 UTC 2023 , Edited by admin on Fri Dec 15 15:05:25 UTC 2023
PRIMARY
ECHA (EC/EINECS)
203-278-3
Created by admin on Fri Dec 15 15:05:25 UTC 2023 , Edited by admin on Fri Dec 15 15:05:25 UTC 2023
PRIMARY
EPA CompTox
DTXSID7022675
Created by admin on Fri Dec 15 15:05:25 UTC 2023 , Edited by admin on Fri Dec 15 15:05:25 UTC 2023
PRIMARY
CHEBI
59170
Created by admin on Fri Dec 15 15:05:25 UTC 2023 , Edited by admin on Fri Dec 15 15:05:25 UTC 2023
PRIMARY
NCI_THESAURUS
C65258
Created by admin on Fri Dec 15 15:05:25 UTC 2023 , Edited by admin on Fri Dec 15 15:05:25 UTC 2023
PRIMARY
MESH
D001625
Created by admin on Fri Dec 15 15:05:25 UTC 2023 , Edited by admin on Fri Dec 15 15:05:25 UTC 2023
PRIMARY
PUBCHEM
7741
Created by admin on Fri Dec 15 15:05:25 UTC 2023 , Edited by admin on Fri Dec 15 15:05:25 UTC 2023
PRIMARY
ChEMBL
CHEMBL1201323
Created by admin on Fri Dec 15 15:05:25 UTC 2023 , Edited by admin on Fri Dec 15 15:05:25 UTC 2023
PRIMARY
ACTIVE MOIETY
Structure of BETAZOLE
SALT/SOLVATE (PARENT)
Structure of BETAZOLE HYDROCHLORIDE
NIH
NCATS
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