U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C6H7N5O
Molecular Weight 165.1527
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1-METHYLGUANINE

SMILES

CN1C(=O)C2=C(N=CN2)N=C1N

InChI

InChIKey=RFLVMTUMFYRZCB-UHFFFAOYSA-N
InChI=1S/C6H7N5O/c1-11-5(12)3-4(9-2-8-3)10-6(11)7/h2H,1H3,(H2,7,10)(H,8,9)

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Formation and repair of tobacco carcinogen-derived bulky DNA adducts.
2010-12-20
Repair of DNA Alkylation Damage by the Escherichia coli Adaptive Response Protein AlkB as Studied by ESI-TOF Mass Spectrometry.
2010-10-27
Nucleotide sequence and genome organization of Dweet mottle virus and its relationship to members of the family Betaflexiviridae.
2010-09
Structural and mutational analysis of Escherichia coli AlkB provides insight into substrate specificity and DNA damage searching.
2010-01-13
A non-heme iron-mediated chemical demethylation in DNA and RNA.
2009-04-21
Recognition and processing of a new repertoire of DNA substrates by human 3-methyladenine DNA glycosylase (AAG).
2009-03-10
Locked nucleoside analogues expand the potential of DNAzymes to cleave structured RNA targets.
2006-06-05
Determination of urinary methylated purine pattern by high-performance liquid chromatography.
2001-02-10
Fast-atom bombardment mass spectrometry for mapping of endogenous methylated purine bases in urine extracts.
1997
Structure-activity relationships for the binding of ligands to xanthine or guanine phosphoribosyl-transferase from Toxoplasma gondii.
1995-11-09
Urinary excretion of modified purines and nucleosides in immunodeficient children.
1985-08
Patents

Patents

Name Type Language
1-METHYLGUANINE
Systematic Name English
NSC-50718
Preferred Name English
N1-METHYLGUANINE
Systematic Name English
6H-PURIN-6-ONE, 2-AMINO-1,9-DIHYDRO-1-METHYL-
Systematic Name English
GUANINE, 1-METHYL-
Systematic Name English
6H-PURIN-6-ONE, 2-AMINO-1,7-DIHYDRO-1-METHYL-
Systematic Name English
Code System Code Type Description
ECHA (EC/EINECS)
213-348-5
Created by admin on Mon Mar 31 21:08:51 GMT 2025 , Edited by admin on Mon Mar 31 21:08:51 GMT 2025
PRIMARY
CAS
938-85-2
Created by admin on Mon Mar 31 21:08:51 GMT 2025 , Edited by admin on Mon Mar 31 21:08:51 GMT 2025
PRIMARY
PUBCHEM
70315
Created by admin on Mon Mar 31 21:08:51 GMT 2025 , Edited by admin on Mon Mar 31 21:08:51 GMT 2025
PRIMARY
EPA CompTox
DTXSID4049377
Created by admin on Mon Mar 31 21:08:51 GMT 2025 , Edited by admin on Mon Mar 31 21:08:51 GMT 2025
PRIMARY
FDA UNII
1ATY0M8242
Created by admin on Mon Mar 31 21:08:51 GMT 2025 , Edited by admin on Mon Mar 31 21:08:51 GMT 2025
PRIMARY
NSC
50718
Created by admin on Mon Mar 31 21:08:51 GMT 2025 , Edited by admin on Mon Mar 31 21:08:51 GMT 2025
PRIMARY
CHEBI
21803
Created by admin on Mon Mar 31 21:08:51 GMT 2025 , Edited by admin on Mon Mar 31 21:08:51 GMT 2025
PRIMARY