1-ETHYL-3-(3-DIMETHYLAMINOPROPYL)CARBODIIMIDE HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H17N3.ClH
Molecular Weight	191.702
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	2
Charge	0

SHOW SMILES / InChI

Structure of 1-ETHYL-3-(3-DIMETHYLAMINOPROPYL)CARBODIIMIDE HYDROCHLORIDE

SMILES

Cl.CCN=C=NCCCN(C)C

InChI

InChIKey=FPQQSJJWHUJYPU-UHFFFAOYSA-N

InChI=1S/C8H17N3.ClH/c1-4-9-8-10-6-5-7-11(2)3;/h4-7H2,1-3H3;1H

HIDE SMILES / InChI

Description

1-Ethyl-3-[3-(dimethylamino)propyl]carbodiimide (EDC) is a water-soluble carbodiimide. EDC is commonly used for the peptide synthesis, protein crosslinking to nucleic acids, preparation of immunoconjugates. EDC is also used in combination with N-hydroxysuccinimide (NHS) for the immobilisation of large biomolecules.

Approval Year

PubMed

Show entries

Title	Date	PubMed
Binding and release of basic fibroblast growth factor from heparinized collagen matrices.	2001 Aug	11456069
Conjugation of monoclonal antibodies with TETA using activated esters: biological comparison of 64Cu-TETA-1A3 with 64Cu-BAT-2IT-1A3.	2001 Dec	11789025
In vivo and in vitro measurement of apoptosis in breast cancer cells using 99mTc-EC-annexin V.	2001 Feb	11279800
Electrochemical detection of sequence-specific DNA using a DNA probe labeled with aminoferrocene and chitosan modified electrode immobilized with ssDNA.	2001 Jan	11205514
The effect of amino acid-modifying reagents on chloroplast protein import and the formation of early import intermediates.	2001 Jan	11181713

Showing 1 to 5 of 35 entries

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Patents

Sample Use Guides

In Vitro Use Guide

Close to 13 mol of EDC per mol of ECF1 was incorporated into the enzyme at 95% inhibition of ATPase activity. Two-thirds of the label was found to be associated with subunit beta with a stoichiometry of about 3 mol of EDC per mol of beta.

Show entries

Name

Type

Language

1-ETHYL-3-(3-DIMETHYLAMINOPROPYL)CARBODIIMIDE HYDROCHLORIDE

Systematic Name

English

1-(3-DIMETHYLAMINOPROPYL)-3-ETHYLCARBODIIMIDE HYDROCHLORIDE

Systematic Name

English

CARBODIIMIDE, (3-(DIMETHYLAMINO)PROPYL)ETHYL-, MONOHYDROCHLORIDE

Common Name

English

WSC

Common Name

English

3-(3-(DIMETHYLAMINO)PROPYL)-1-ETHYLCARBODIIMIDE HYDROCHLORIDE

Systematic Name

English

Showing 1 to 5 of 14 entries

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Code System

Code

Type

Description

MERCK INDEX

m4825

PRIMARY

Merck Index

PUBCHEM

2723939

PRIMARY

ECHA (EC/EINECS)

247-361-2

PRIMARY

CAS

25952-53-8

PRIMARY

EPA CompTox

DTXSID50880076

PRIMARY

Showing 1 to 5 of 7 entries

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SUBSTANCE RECORD


					19W5TL0WJ4

1-ETHYL-3-(3-DIMETHYLAMINOPROPYL)CARBODIIMIDE HYDROCHLORIDE