Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C16H25NO2 |
| Molecular Weight | 263.3752 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(C)C[C@H](C1=CC=C(O)C=C1)C2(O)CCCCC2
InChI
InChIKey=KYYIDSXMWOZKMP-OAHLLOKOSA-N
InChI=1S/C16H25NO2/c1-17(2)12-15(13-6-8-14(18)9-7-13)16(19)10-4-3-5-11-16/h6-9,15,18-19H,3-5,10-12H2,1-2H3/t15-/m1/s1
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Pharmacokinetic and pharmacodynamic profiles of the novel serotonin and norepinephrine reuptake inhibitor desvenlafaxine succinate in ovariectomized Sprague-Dawley rats. | 2006 Jul 7 |
|
| A double-blind, placebo-controlled study of the efficacy and safety of desvenlafaxine succinate in the treatment of major depressive disorder. | 2007 May |
|
| A randomized, double-blind, placebo-controlled trial of desvenlafaxine succinate in adult outpatients with major depressive disorder. | 2007 Nov |
|
| [Pharmacotherapy of depression: recent developments]. | 2007 Sep 19 |
|
| Are SNRIs more effective than SSRIs? A review of the current state of the controversy. | 2008 |
|
| An assessment of drug-drug interactions: the effect of desvenlafaxine and duloxetine on the pharmacokinetics of the CYP2D6 probe desipramine in healthy subjects. | 2008 Dec |
|
| Efficacy and tolerability of desvenlafaxine succinate treatment for menopausal vasomotor symptoms: a randomized controlled trial. | 2008 Jan |
|
| Desvenlafaxine succinate for major depressive disorder. | 2008 Jul |
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| A pooled analysis of two placebo-controlled trials of desvenlafaxine in major depressive disorder. | 2008 Jul |
|
| Efficacy, safety, and tolerability of desvenlafaxine 50 mg/day and 100 mg/day in outpatients with major depressive disorder. | 2008 Jul |
|
| Desvenlafaxine: another "me too" drug? | 2008 Oct |
|
| Efficacy, safety, and tolerability of fixed-dose desvenlafaxine 50 and 100 mg/day for major depressive disorder in a placebo-controlled trial. | 2008 Sep |
|
| Desvenlafaxine and venlafaxine exert minimal in vitro inhibition of human cytochrome P450 and P-glycoprotein activities. | 2009 |
|
| Treatment of psychotic symptoms in bipolar disorder with aripiprazole monotherapy: a meta-analysis. | 2009 Dec 31 |
|
| Drug approvals: '08 in review. Desvenlafaxine (Pristiq). | 2009 Feb |
|
| Comparison of the pharmacokinetics of venlafaxine extended release and desvenlafaxine in extensive and poor cytochrome P450 2D6 metabolizers. | 2009 Feb |
|
| The effects of desvenlafaxine and paroxetine on the pharmacokinetics of the cytochrome P450 2D6 substrate desipramine in healthy adults. | 2009 Feb |
|
| Preliminary data concerning the reliability and psychometric properties of the Greek translation of the 20-item Subjective Well-Being Under Neuroleptic Treatment Scale (SWN-20). | 2009 Jan 21 |
|
| An integrated analysis of the efficacy of desvenlafaxine compared with placebo in patients with major depressive disorder. | 2009 Mar |
|
| Optimal dosing of desvenlafaxine, new insights in gambling and anorexia, and caffeine-induced psychosis. | 2009 Mar |
|
| Desvenlafaxine for the treatment of vasomotor symptoms associated with menopause: a double-blind, randomized, placebo-controlled trial of efficacy and safety. | 2009 Mar |
|
| Desvenlafaxine: application withdrawal. Desvenlafaxine: withdrawal of marketing application for depression also. | 2009 Oct |
|
| Desvenlafaxine. | 2009 Oct-Dec |
|
| Short-term efficacy and safety of desvenlafaxine in a randomized, placebo-controlled study of perimenopausal and postmenopausal women with major depressive disorder. | 2010 Aug |
|
| Pharmacological and clinical profile of newer antidepressants: implications for the treatment of elderly patients. | 2010 Aug 1 |
|
| Optimal management of perimenopausal depression. | 2010 Aug 9 |
|
| Assessment of infant dose through milk in a lactating woman taking amisulpride and desvenlafaxine for treatment-resistant depression. | 2010 Dec |
|
| A comparative study on the effects of Hypericum Perforatum and passion flower on the menopausal symptoms of women referring to Isfahan city health care centers. | 2010 Fall |
|
| Desvenlafaxine for the prevention of relapse in major depressive disorder: results of a randomized trial. | 2010 Feb |
|
| Correction of venlafaxine- and duloxetine-induced transaminase elevations with desvenlafaxine in a patient with Gilbert's syndrome. | 2010 Jan |
|
| Desvenlafaxine succinate: a newer antidepressant for the treatment of depression and somatic symptoms. | 2010 Jan |
|
| Update on antithrombotic therapy for stroke prevention in atrial fibrillation. | 2010 Jun |
|
| Desvenlafaxine in major depressive disorder: an evidence-based review of its place in therapy. | 2010 Jun 15 |
|
| Gene expression profile analysis of genes in rat hippocampus from antidepressant treated rats using DNA microarray. | 2010 Nov 30 |
|
| Desvenlafaxine as a possible cause of acquired hemophilia. | 2010 Nov-Dec |
Patents
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| Code System | Code | Type | Description | ||
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9816723
Created by
admin on Sat Dec 16 01:34:38 GMT 2023 , Edited by admin on Sat Dec 16 01:34:38 GMT 2023
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PRIMARY | |||
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142761-12-4
Created by
admin on Sat Dec 16 01:34:38 GMT 2023 , Edited by admin on Sat Dec 16 01:34:38 GMT 2023
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PRIMARY | |||
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189BFR45S0
Created by
admin on Sat Dec 16 01:34:38 GMT 2023 , Edited by admin on Sat Dec 16 01:34:38 GMT 2023
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PRIMARY | |||
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273749-38-5
Created by
admin on Sat Dec 16 01:34:38 GMT 2023 , Edited by admin on Sat Dec 16 01:34:38 GMT 2023
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SUPERSEDED |
SUBSTANCE RECORD
