DG-041

Details

Stereochemistry	ACHIRAL
Molecular Formula	C23H15Cl4FN2O3S2
Molecular Weight	592.317
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=CN(CC2=CC=C(Cl)C=C2Cl)C3=C1C=C(F)C=C3\C=C\C(=O)NS(=O)(=O)C4=CC(Cl)=C(Cl)S4

InChI

InChIKey=BFBTVZNKWXWKNZ-HWKANZROSA-N

InChI=1S/C23H15Cl4FN2O3S2/c1-12-10-30(11-14-2-4-15(24)7-18(14)25)22-13(6-16(28)8-17(12)22)3-5-20(31)29-35(32,33)21-9-19(26)23(27)34-21/h2-10H,11H2,1H3,(H,29,31)/b5-3+

HIDE SMILES / InChI

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Prostaglandin E2 receptor EP3 subtype 4 Target ID: P43115\|\|\|Q16546 Gene ID: 5733.0 Gene Symbol: PTGER3 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/19957930	Antagonist 2778		4.6 nM [IC50]

PubMed

Title	Date	PubMed
Modulation of bladder function by prostaglandin EP3 receptors in the central nervous system.	2008 Oct	18632791

Patents

Name

Type

Language

DG-041

Common Name

English

2-PROPENAMIDE, 3-(1-((2,4-DICHLOROPHENYL)METHYL)-5-FLUORO-3-METHYL-1H-INDOL-7-YL)-N-((4,5-DICHLORO-2-THIENYL)SULFONYL)-, (2E)-

Systematic Name

English

Code System Code Type Description

CAS

1030374-84-5