Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C22H25BrN4O2 |
| Molecular Weight | 457.364 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC2=NC=NC3=C2C=C1OCCCCCN(C)CC4=CC=C(Br)C=C4N3
InChI
InChIKey=JXDYOSVKVSQGJM-UHFFFAOYSA-N
InChI=1S/C22H25BrN4O2/c1-27-8-4-3-5-9-29-21-11-17-19(12-20(21)28-2)24-14-25-22(17)26-18-10-16(23)7-6-15(18)13-27/h6-7,10-12,14H,3-5,8-9,13H2,1-2H3,(H,24,25,26)
Approval Year
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Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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CHEMBL3545133
Created by
admin on Sat Dec 16 11:32:25 GMT 2023 , Edited by admin on Sat Dec 16 11:32:25 GMT 2023
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PRIMARY | |||
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807640-87-5
Created by
admin on Sat Dec 16 11:32:25 GMT 2023 , Edited by admin on Sat Dec 16 11:32:25 GMT 2023
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PRIMARY | |||
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JNJ-26483327
Created by
admin on Sat Dec 16 11:32:25 GMT 2023 , Edited by admin on Sat Dec 16 11:32:25 GMT 2023
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PRIMARY | |||
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JNJ-26483327
Created by
admin on Sat Dec 16 11:32:25 GMT 2023 , Edited by admin on Sat Dec 16 11:32:25 GMT 2023
|
PRIMARY | Official Title: An Open-label, Phase I Study to Determine the Safety and Pharmacokinetics of JNJ-26483327, a Multi-targeted Kinase Inhibitor, Administered to Subjects With Advanced Stage and/or Refractory Solid MalignanciesDetailed Description:JNJ-26483327, a multi-targeted reversible kinase inhibitor, is a new drug in development for treatment of cancer. This study will test the safety (the effect on the body) of JNJ-26483327 and the highest dose of JNJ-26483327 that patients with advanced cancer can tolerate will be determined. Antitumor activity of JNJ-26481585 will be evaluated. | ||
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11952856
Created by
admin on Sat Dec 16 11:32:25 GMT 2023 , Edited by admin on Sat Dec 16 11:32:25 GMT 2023
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16720VER1H
Created by
admin on Sat Dec 16 11:32:25 GMT 2023 , Edited by admin on Sat Dec 16 11:32:25 GMT 2023
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PRIMARY | |||
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C77866
Created by
admin on Sat Dec 16 11:32:25 GMT 2023 , Edited by admin on Sat Dec 16 11:32:25 GMT 2023
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PRIMARY |
ACTIVE MOIETY
