EDOXUDINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C11H16N2O5
Molecular Weight	256.2551
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of EDOXUDINE

Structure Search

SMILES

CCC1=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)NC1=O

InChI

InChIKey=XACKNLSZYYIACO-DJLDLDEBSA-N

InChI=1S/C11H16N2O5/c1-2-6-4-13(11(17)12-10(6)16)9-3-7(15)8(5-14)18-9/h4,7-9,14-15H,2-3,5H2,1H3,(H,12,16,17)/t7-,8+,9+/m0/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1894930 | https://www.ncbi.nlm.nih.gov/pubmed/14743269

Edoxudine (5-ethyl-2'-deoxyuridine), an antiviral drug, has been clinically studied against the recurrent genital herpes.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Relative potencies of different anti-herpes agents in the topical treatment of cutaneous herpes simplex virus infection of athymic nude mice.	1979 Nov	526011
Synthesis and antitumor and antiviral properties of 5-alkyl-2'-deoxyuridines, 3',5'-cyclic monophosphates, and neutral cyclic triesters.	1986 Apr	3959027
Comparison of susceptibilities of varicella-zoster virus and herpes simplex viruses to nucleoside analogs.	1986 Mar	3013088
Thymidine and thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase.	2003 Sep 15	12941330
3D-QSAR studies on antitubercular thymidine monophosphate kinase inhibitors based on different alignment methods.	2006 Feb 15	16290929

Patents

Patents

Sample Use Guides

In Vivo Use Guide

topical edoxudine 3.0% cream

Route of Administration: Topical

Name

Type

Language

EDOXUDINE

Official Name

English

EDU

Common Name

English

URIDINE, 2'-DEOXY-5-ETHYL-

Systematic Name

English

2'-DEOXY-5-ETHYLURIDINE

Systematic Name

English

ORF-15817

Code

English

EDOXUDINE [USAN]

Common Name

English

EUDR

Common Name

English

Edoxudine [WHO-DD]

Common Name

English

5-ETHYL-3-(2'-DEOXYRIBOSYL)URACIL

Common Name

English

EDOXUDINE [MI]

Common Name

English

ORF 15817

Code

English

RWJ-15817

Code

English

RWJ 15817

Code

English

5-ETHYL-2'-DEOXYURIDINE

Systematic Name

English

NSC-758405

Code

English

edoxudine [INN]

Common Name

English

EDOXUDINE [MART.]

Common Name

English

Classification Tree Code System Code

WHO-VATC

QD06BB09

Created by admin on Fri Dec 15 15:23:19 GMT 2023 , Edited by admin on Fri Dec 15 15:23:19 GMT 2023

WHO-ATC

D06BB09

Created by admin on Fri Dec 15 15:23:19 GMT 2023 , Edited by admin on Fri Dec 15 15:23:19 GMT 2023

NCI_THESAURUS

C29575

Created by admin on Fri Dec 15 15:23:19 GMT 2023 , Edited by admin on Fri Dec 15 15:23:19 GMT 2023

NCI_THESAURUS

C281

Created by admin on Fri Dec 15 15:23:19 GMT 2023 , Edited by admin on Fri Dec 15 15:23:19 GMT 2023

Code System Code Type Description

CAS

15176-29-1

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SMS_ID

100000080512

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ChEMBL

CHEMBL318153

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EVMPD

SUB06460MIG

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MERCK INDEX

m4833

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Merck Index

PUBCHEM

66377

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NSC

758405

Created by admin on Fri Dec 15 15:23:19 GMT 2023 , Edited by admin on Fri Dec 15 15:23:19 GMT 2023

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EPA CompTox

DTXSID4045890

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RXCUI

49428

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RxNorm

NCI_THESAURUS

C87662

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FDA UNII

15ZQM81Y3R

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MESH

C022811

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ECHA (EC/EINECS)

239-226-1

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DRUG BANK

DB13421

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INN

5512

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DRUG CENTRAL

3173

Created by admin on Fri Dec 15 15:23:19 GMT 2023 , Edited by admin on Fri Dec 15 15:23:19 GMT 2023

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WIKIPEDIA

EDOXUDINE

Created by admin on Fri Dec 15 15:23:19 GMT 2023 , Edited by admin on Fri Dec 15 15:23:19 GMT 2023

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USAN

U-62

Created by admin on Fri Dec 15 15:23:19 GMT 2023 , Edited by admin on Fri Dec 15 15:23:19 GMT 2023

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ACTIVE MOIETY


					15ZQM81Y3R

EDOXUDINE