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Details

Stereochemistry ACHIRAL
Molecular Formula C25H25F3N4O4
Molecular Weight 502.4856
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NAPORAFENIB

SMILES

CC1=CC=C(NC(=O)C2=CC=NC(=C2)C(F)(F)F)C=C1C3=CC(OCCO)=NC(=C3)N4CCOCC4

InChI

InChIKey=UEPXBTCUIIGYCY-UHFFFAOYSA-N
InChI=1S/C25H25F3N4O4/c1-16-2-3-19(30-24(34)17-4-5-29-21(12-17)25(26,27)28)15-20(16)18-13-22(32-6-9-35-10-7-32)31-23(14-18)36-11-8-33/h2-5,12-15,33H,6-11H2,1H3,(H,30,34)

HIDE SMILES / InChI

Approval Year

Name Type Language
NAPORAFENIB
INN  
Official Name English
LXH-254
Code English
PAN-RAF INHIBITOR LXH254
Code English
LXH254
Code English
N-(3-(2-(HYDROXYETHOXY)-6-(MORPHOLIN-4-YL) PYRIDIN-4-YL)-4-METHYLPHENYL)-2-(TRIFLUOROMETHYL)PYRIDINE-4-CARBOXAMIDE
Systematic Name English
naporafenib [INN]
Common Name English
4-PYRIDINECARBOXAMIDE, N-(3-(2-(2-HYDROXYETHOXY)-6-(4-MORPHOLINYL)-4-PYRIDINYL)-4-METHYLPHENYL)-2-(TRIFLUOROMETHYL)-)-
Systematic Name English
Naporafenib [WHO-DD]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C129825
Created by admin on Sat Dec 16 10:40:32 GMT 2023 , Edited by admin on Sat Dec 16 10:40:32 GMT 2023
NCI_THESAURUS C2336
Created by admin on Sat Dec 16 10:40:32 GMT 2023 , Edited by admin on Sat Dec 16 10:40:32 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C125003
Created by admin on Sat Dec 16 10:40:32 GMT 2023 , Edited by admin on Sat Dec 16 10:40:32 GMT 2023
PRIMARY
FDA UNII
15JL80DG6H
Created by admin on Sat Dec 16 10:40:32 GMT 2023 , Edited by admin on Sat Dec 16 10:40:32 GMT 2023
PRIMARY
SMS_ID
300000027517
Created by admin on Sat Dec 16 10:40:32 GMT 2023 , Edited by admin on Sat Dec 16 10:40:32 GMT 2023
PRIMARY
CAS
1800398-38-2
Created by admin on Sat Dec 16 10:40:32 GMT 2023 , Edited by admin on Sat Dec 16 10:40:32 GMT 2023
PRIMARY
PUBCHEM
90456533
Created by admin on Sat Dec 16 10:40:32 GMT 2023 , Edited by admin on Sat Dec 16 10:40:32 GMT 2023
PRIMARY
INN
11398
Created by admin on Sat Dec 16 10:40:32 GMT 2023 , Edited by admin on Sat Dec 16 10:40:32 GMT 2023
PRIMARY