| Stereochemistry | ACHIRAL |
| Molecular Formula | C17H18N4O3S |
| Molecular Weight | 358.415 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 1 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)S(=O)(=O)N1C(N)=NC2=C1C=C(C=C2)C(=N\O)\C3=CC=CC=C3
InChI
InChIKey=IWKXBHQELWQLHF-CAPFRKAQSA-N
InChI=1S/C17H18N4O3S/c1-11(2)25(23,24)21-15-10-13(8-9-14(15)19-17(21)18)16(20-22)12-6-4-3-5-7-12/h3-11,22H,1-2H3,(H2,18,19)/b20-16+
Enviroxime (LY 122772 or 2-amino-1-(isopropyl sulphonyl)-6-benzimidazole phenyl ketone oxime) is an benzimidazole antiviral agent. Enviroxime inhibits the replication of rhinoviruses and enteroviruses, additionally it impedes the replication of the hepatitis C virus. Enviroxime targets the 3A coding region of rhinovirus and poliovirus. Enviroxime is able to inhibit host phosphatidylinositol 4-kinase III.
Originator
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
| 40.0 nM [IC50] | |||
PubMed
ACTIVE MOIETY
