U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C11H14FNO3
Molecular Weight 226.2347
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Floretyrosine F18

SMILES

N[C@@H](CC1=CC=C(OCC[18F])C=C1)C(O)=O

InChI

InChIKey=QZZYPHBVOQMBAT-LRAGLOQXSA-N
InChI=1S/C11H14FNO3/c12-5-6-16-9-3-1-8(2-4-9)7-10(13)11(14)15/h1-4,10H,5-7,13H2,(H,14,15)/t10-/m0/s1/i12-1

HIDE SMILES / InChI
18F-FET (18F-Fluoroethyl-L-tyrosine) is a radiolabelled amino acid. It penetrates the blood-brain barrier by a specific amino acid transport system. In the brain, it is taken up into upregulated tumoral cells but not incorporated into proteins. It is used as a biomarker for positron emission tomography for imaging brain tumors, where it has higher specificity than 18F-FDG.

Approval Year

Name Type Language
Floretyrosine F18
USAN  
Official Name English
J1.857.391A
Code English
FLUOROETHYL-L-TYROSINE (18F)
Common Name English
Fluoroethyl-L-tyrosine (18F) [WHO-DD]
Common Name English
FET F-18
Common Name English
FLORETYROSINE F18 [USAN]
Common Name English
18F-FET
Common Name English
O-[2-(fluoro-<sup>18</sup>F)ethyl]-L-Tyrosine
Systematic Name English
FLUOROETHYLTYROSINE F-18
Common Name English
L-Tyrosine, O-[2-(fluoro-<sup>18</sup>F)ethyl]-
Systematic Name English
2-FLUOROETHYLTYROSINE F-18
Common Name English
Classification Tree Code System Code
WHO-ATC V09IX10
Created by admin on Sat Dec 16 01:49:12 GMT 2023 , Edited by admin on Sat Dec 16 01:49:12 GMT 2023
FDA ORPHAN DRUG 683619
Created by admin on Sat Dec 16 01:49:12 GMT 2023 , Edited by admin on Sat Dec 16 01:49:12 GMT 2023
FDA ORPHAN DRUG 934623
Created by admin on Sat Dec 16 01:49:12 GMT 2023 , Edited by admin on Sat Dec 16 01:49:12 GMT 2023
FDA ORPHAN DRUG 767920
Created by admin on Sat Dec 16 01:49:12 GMT 2023 , Edited by admin on Sat Dec 16 01:49:12 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C60818
Created by admin on Sat Dec 16 01:49:12 GMT 2023 , Edited by admin on Sat Dec 16 01:49:12 GMT 2023
PRIMARY
USAN
LM-155
Created by admin on Sat Dec 16 01:49:12 GMT 2023 , Edited by admin on Sat Dec 16 01:49:12 GMT 2023
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DRUG BANK
DB15405
Created by admin on Sat Dec 16 01:49:12 GMT 2023 , Edited by admin on Sat Dec 16 01:49:12 GMT 2023
PRIMARY
CAS
178433-03-9
Created by admin on Sat Dec 16 01:49:12 GMT 2023 , Edited by admin on Sat Dec 16 01:49:12 GMT 2023
PRIMARY
EPA CompTox
DTXSID601045942
Created by admin on Sat Dec 16 01:49:12 GMT 2023 , Edited by admin on Sat Dec 16 01:49:12 GMT 2023
PRIMARY
SMS_ID
100000169818
Created by admin on Sat Dec 16 01:49:12 GMT 2023 , Edited by admin on Sat Dec 16 01:49:12 GMT 2023
PRIMARY
CAS
1325243-02-4
Created by admin on Sat Dec 16 01:49:12 GMT 2023 , Edited by admin on Sat Dec 16 01:49:12 GMT 2023
SUPERSEDED
EVMPD
SUB183603
Created by admin on Sat Dec 16 01:49:12 GMT 2023 , Edited by admin on Sat Dec 16 01:49:12 GMT 2023
PRIMARY
FDA UNII
1326R5J1IA
Created by admin on Sat Dec 16 01:49:12 GMT 2023 , Edited by admin on Sat Dec 16 01:49:12 GMT 2023
PRIMARY
PUBCHEM
9834479
Created by admin on Sat Dec 16 01:49:12 GMT 2023 , Edited by admin on Sat Dec 16 01:49:12 GMT 2023
PRIMARY
WIKIPEDIA
Fluoroethyl-L-tyrosine (18F)
Created by admin on Sat Dec 16 01:49:12 GMT 2023 , Edited by admin on Sat Dec 16 01:49:12 GMT 2023
PRIMARY