Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C29H36N6O6S.ClH |
| Molecular Weight | 633.159 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CSCC[C@H](NC(=O)[C@@H](N)CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC3=CC=CC=C3)C(N)=O
InChI
InChIKey=BABSBRZDEYUBSD-RJPXAACDSA-N
InChI=1S/C29H36N6O6S.ClH/c1-42-12-11-22(33-27(39)20(30)14-18-16-32-21-10-6-5-9-19(18)21)28(40)35-24(15-25(36)37)29(41)34-23(26(31)38)13-17-7-3-2-4-8-17;/h2-10,16,20,22-24,32H,11-15,30H2,1H3,(H2,31,38)(H,33,39)(H,34,41)(H,35,40)(H,36,37);1H/t20-,22-,23-,24-;/m0./s1
DescriptionCurator's Comment: Description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/21261669
Curator's Comment: Description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/21261669
Tetragastrin is a C-terminal tetrapeptide (Trp–Met–Asp–Phe–NH2) of gastrin. It is the smallest peptide fragment of gastrin which has the same physiological and pharmacological activity as gastrin. It is used to test the secretion of digestive juice. It causes severe anxiety symptoms when administered to humans and is commonly used in scientific research to induce panic attacks for the purpose of testing new anxiolytic drugs. Tetragastrin is a selective cholecystokinin B (CCKB) receptor agonist. Tetragastrin is used as a gastric stimulant at a dose of 4 ug/kg, it was marketed in Japan under the brand name Gastopsin.
CNS Activity
Originator
Approval Year
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| Code System | Code | Type | Description | ||
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13050781
Created by
admin on Fri Dec 15 15:39:29 GMT 2023 , Edited by admin on Fri Dec 15 15:39:29 GMT 2023
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PRIMARY | |||
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130LLV7CL9
Created by
admin on Fri Dec 15 15:39:29 GMT 2023 , Edited by admin on Fri Dec 15 15:39:29 GMT 2023
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5609-49-4
Created by
admin on Fri Dec 15 15:39:29 GMT 2023 , Edited by admin on Fri Dec 15 15:39:29 GMT 2023
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PRIMARY |
ACTIVE MOIETY
SUBSTANCE RECORD
