APX-3330

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H30O6
Molecular Weight	378.4593
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCCCCCC\C(=C/C1=C(C)C(=O)C(OC)=C(OC)C1=O)C(O)=O

InChI

InChIKey=AALSSIXXBDPENJ-FYWRMAATSA-N

InChI=1S/C21H30O6/c1-5-6-7-8-9-10-11-12-15(21(24)25)13-16-14(2)17(22)19(26-3)20(27-4)18(16)23/h13H,5-12H2,1-4H3,(H,24,25)/b15-13+

HIDE SMILES / InChI

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
DNA-(apurinic or apyrimidinic site) lyase 8 Target ID: P27695 Gene ID: 328.0 Gene Symbol: APEX1 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/17053053	Inhibitor 8146
DNA-(apurinic or apyrimidinic site) lyase 8 Target ID: CHEMBL5619 Sources: https://www.ncbi.nlm.nih.gov/pubmed/10932159	Inhibitor 8146		1.6 nM [Kd]

Name

Type

Language

APX-3330

Code

English

APX3330

Code

English

E 3330

Code

English

APE1/REF-1 REDOX INHIBITOR APX3330

Common Name

English

APX 3330

Code

English

E-3330

Code

English

UNDECANOIC ACID, 2-((4,5-DIMETHOXY-2-METHYL-3,6-DIOXO-1,4-CYCLOHEXADIEN-1-YL)METHYLENE)-, (2E)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

6439397

Created by admin on Sat Dec 17 01:46:54 UTC 2022 , Edited by admin on Sat Dec 17 01:46:54 UTC 2022

PRIMARY

CAS

136164-66-4

Created by admin on Sat Dec 17 01:46:54 UTC 2022 , Edited by admin on Sat Dec 17 01:46:54 UTC 2022

PRIMARY

FDA UNII

11267UI968

Created by admin on Sat Dec 17 01:46:54 UTC 2022 , Edited by admin on Sat Dec 17 01:46:54 UTC 2022

PRIMARY

NCI_THESAURUS

C150216

Created by admin on Sat Dec 17 01:46:54 UTC 2022 , Edited by admin on Sat Dec 17 01:46:54 UTC 2022

PRIMARY

NCIT

ACTIVE MOIETY


					11267UI968

APX-3330