1H-1,2,4-TRIAZOLE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C2H3N3
Molecular Weight	69.0653
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

N1C=NC=N1

InChI

InChIKey=NSPMIYGKQJPBQR-UHFFFAOYSA-N

InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
The susceptibility of certain microbial strains to fused 1,2,4-triazole derivatives.	2004	16146058
Synthesis and potential antimycotic activity of 4-substituted-3-(thiophene-2-yl-methyl)-Delta2-1,2,4-triazoline-5-thiones.	2004 Sep	15610621
Double-headed acyclo C-nucleoside analogues. Functionalized 1,2-bis-(1,2,4-triazol-3-yl)ethane-1,2-diol.	2005	16438055
Microwave irradiation for accelerating the synthesis of acyclonucleosides of 1,2,4-triazole.	2005	16247964
Synthesis and antituberculosis activity of new 3-alkylsulfanyl-1,2,4-triazole derivatives.	2005 Apr	15968822
Copper(I) 1,2,4-triazolates and related complexes: studies of the solvothermal ligand reactions, network topologies, and photoluminescence properties.	2005 Apr 20	15826187
Triazolium-based energetic ionic liquids.	2005 Aug 18	16834094
Catalase inhibition by amino triazole induces oxidative stress in goldfish brain.	2005 Aug 9	16023088
Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors.	2005 Dec 1	16198562
Three 1,2,4-triazole derivatives containing substituted benzyl and benzylamino groups.	2005 Feb	15695905
1-butyl-3-methylimidazolium 3,5-dinitro-1,2,4-triazolate: a novel ionic liquid containing a rigid, planar energetic anion.	2005 Feb 21	15700064
Solid-phase synthesis of 5-amino-1-(substituted thiocarbamoyl)pyrazole and 1,2,4-triazole derivatives via dithiocarbazate linker.	2005 Jan-Feb	15638493
Energetic azolium azolate salts.	2005 Jul 11	15998035
Phthalazine PDE IV inhibitors: conformational study of some 6-methoxy-1,4-disubstituted derivatives.	2005 Jul 15	15927474
An efficient synthesis of achiral and chiral 1,2,4-triazolium salts: bench stable precursors for N-heterocyclic carbenes.	2005 Jul 8	15989360
4,4'-Butane-1,4-diylbis[3-ethyl-1H-1,2,4-triazol-5(4H)-one] and 4-hydroxy-3-n-propyl-1H-1,2,4-triazol-5(4H)-one.	2005 Jun	15930685
Optimized block-wise variable combination by particle swarm optimization for partial least squares modeling in quantitative structure-activity relationship studies.	2005 Mar-Apr	15807514
Carbonic anhydrase inhibitors. Inhibition of the cytosolic and tumor-associated carbonic anhydrase isozymes I, II, and IX with a series of 1,3,4-thiadiazole- and 1,2,4-triazole-thiols.	2005 May 2	15837323
Adaptive response of antioxidant enzymes to catalase inhibition by aminotriazole in goldfish liver and kidney.	2005 Nov	16168691
Synthesis and some first-row transition-metal complexes of the 1,2,4-triazole-based Bis(terdentate) ligands TsPMAT and PMAT.	2005 Nov 18	16163767
Metal ion coordination to azole nucleosides.	2005 Oct 21	16075445
Syntheses, structures, and magnetic properties of unusual nonlinear polynuclear copper(II) complexes containing derivatives of 1,2,4-triazole and pivalate ligands.	2005 Oct 31	16241151
Tuning of redox properties for the design of ruthenium anticancer drugs: part 2. Syntheses, crystal structures, and electrochemistry of potentially antitumor [Ru III/II Cl6-n(Azole)n]z(n = 3, 4, 6) complexes.	2005 Sep 19	16156629
Determination of 22 triazole compounds including parent fungicides and metabolites in apples, peaches, flour, and water by liquid chromatography/tandem mass spectrometry.	2005 Sep-Oct	16386000
Influence of garlic, synthetic 1,2,4-triasole derivative and herbal preparation echinovit C on selected indices of turkey-hens non-specific immunity.	2006	16573275
Electronic properties, redox behavior, and interactions with H2O2 of pH-sensitive hydroxyphenyl-1,2,4-triazole-based oxovanadium(V) complexes.	2006 Apr 3	16562946
Metal-organic frameworks incorporating Cu3(mu3-OH) clusters.	2006 Aug 21	16883403
A computational study on pi and sigma modes of metal ion binding to heteroaromatics (CH)(5-m)X(m) and (CH)(6-m)X(m) (X = N and P): contrasting preferences between nitrogen- and phosphorous-substituted rings.	2006 Aug 24	16913690
Synthesis, characterization, and in vitro antitumor properties of tris(hydroxymethyl)phosphine copper(I) complexes containing the new bis(1,2,4-triazol-1-yl)acetate ligand.	2006 Dec 14	17149861
Quantum chemical study of the structure and thermochemistry of the five-membered nitrogen-containing heterocycles and their anions and radicals.	2006 Dec 28	17181359
Synthesis of cyclopentenyl carbocyclic nucleosides as potential antiviral agents against orthopoxviruses and SARS.	2006 Feb 9	16451078
Discovery of novel triazole-based opioid receptor antagonists.	2006 Jul 13	16821764
Synthesis and characterization of a 3D coordination polymer based on trinuclear triangular CuII as secondary building units.	2006 Jul 24	16841984
Synthesis and CYP26A1 inhibitory activity of 1-[benzofuran-2-yl-(4-alkyl/aryl-phenyl)-methyl]-1H-triazoles.	2006 Jun 1	16458519
Photoresponsive molecular wires of FeII triazole complexes in organic media and light-induced morphological transformations.	2006 Jun 21	16758009
Microwave-assisted organic synthesis of 3-(D-Gluco-pentitol-1-yl)-1H-1,2,4-triazole.	2006 Mar	16629125
Three-dimensional networks of lanthanide 1,2,4-triazolates: infinity(3)[Yb(Tz)3] and [Eu2(Tz)5(TzH)2], the first 4f networks with complete nitrogen coordination.	2006 May 21	16767275
Photodegradation kinetics of some thiols and thiones in aqueous suspension of zinc oxide.	2006 May-Jun	16856757
Solid-state coordination chemistry of the Cu/triazolate/X system (X = F-, Cl-, Br-, I-, OH-, and SO4(2-)).	2006 Nov 13	17083234
Experimental and theoretical study of the coordination of 1,2,4-triazolato, tetrazolato, and pentazolato ligands to the [K(18-crown-6)]+ fragment.	2006 Oct 16	17029381
Molecular simulation study of some thermophysical and transport properties of triazolium-based ionic liquids.	2006 Sep 14	16956294
Synthesis and light-emitting properties of bipolar oligofluorenes containing triarylamine and 1,2,4-triazole moieties.	2006 Sep 14	16956204
Nondegenerate pi-donor/pi-acceptor [2]catenanes containing proton-ionizable 1H-1,2,4-triazole subunits: synthesis and spontaneous resolution.	2007	17330312
Synthesis of 1,2,4-triazole C-nucleosides from hydrazonyl chlorides and nitriles.	2007	17162585
Visible spectra of type II cytochrome P450-drug complexes: evidence that "incomplete" heme coordination is common.	2007 Apr	17251307
In situ solvothermal generation of 1,2,4-triazolates and related compounds from organonitrile and hydrazine hydrate: a mechanism study.	2007 Feb 19	17291112
Highly potent triazole-based tubulin polymerization inhibitors.	2007 Feb 22	17249649
Differential reactivity of alpha and beta 2'-deoxyribonucleosides towards protonation and metalation.	2007 Mar	17207532
3D-QSAR study of sulfonamide inhibitors of human carbonic anhydrase II.	2007 Mar	17118494
Assessing the data quality in predictive toxicology using a panel of cell lines and cytotoxicity assays.	2007 Mar 15	17266913

Patents

Name

Type

Language

1H-1,2,4-TRIAZOLE

Systematic Name

English

EFINACONAZOLE METABOLITE H1

Common Name

English

TRIAZOLE, 1H,1,2,4-

Common Name

English

PYRRODIAZOLE

Common Name

English

1H-1,2,4-TRIAZOLE [MI]

Common Name

English

1H-1,2,4-TRIAZOLE [HSDB]

Common Name

English

NSC-83128

Code

English

Classification Tree Code System Code

EPA PESTICIDE CODE

600074