Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C21H32O2 |
Molecular Weight | 316.4776 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 7 / 7 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC[C@@]3([H])[C@@]2([H])CC[C@]4([H])CC(=O)CC[C@]34C
InChI
InChIKey=XMRPGKVKISIQBV-XWOJZHJZSA-N
InChI=1S/C21H32O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h14,16-19H,4-12H2,1-3H3/t14-,16+,17-,18+,19+,20+,21-/m1/s1
Approval Year
PubMed
Title | Date | PubMed |
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A PXR reporter gene assay in a stable cell culture system: CYP3A4 and CYP2B6 induction by pesticides. | 2004 Dec 15 |
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Modulation of the firing activity of female dorsal raphe nucleus serotonergic neurons by neuroactive steroids. | 2004 Jul |
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Insight into the mechanism of action of neuroactive steroids. | 2004 Jul |
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Identification of 3beta,5beta-tetrahydroprogesterone, a progesterone metabolite, and its stimulatory action on preoptic neurons in the avian brain. | 2004 May 8 |
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Metabolites of progesterone and the pregnane X receptor: a novel pathway regulating uterine contractility in pregnancy? | 2005 Apr |
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Plasma concentrations of neuroactive steroids before and after electroconvulsive therapy in major depression. | 2005 Jun |
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Oestrogen and testosterone modulate the firing activity of dorsal raphe nucleus serotonergic neurones in both male and female rats. | 2005 Mar |
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3alpha-reduced neuroactive steroids and their precursors during pregnancy and the postpartum period. | 2005 Nov |
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Molecular cloning and heterologous expression of progesterone 5beta-reductase from Digitalis lanata Ehrh. | 2006 Feb |
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Influence of mirtazapine on plasma concentrations of neuroactive steroids in major depression and on 3alpha-hydroxysteroid dehydrogenase activity. | 2006 Mar |
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The crystal structure of human Delta4-3-ketosteroid 5beta-reductase defines the functional role of the residues of the catalytic tetrad in the steroid double bond reduction mechanism. | 2008 Aug 12 |
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The crystal structure of progesterone 5beta-reductase from Digitalis lanata defines a novel class of short chain dehydrogenases/reductases. | 2008 Jun 20 |
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Metabolism of neuroactive steroids in day-old chick brain. | 2009 Apr |
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The VEP1 gene (At4g24220) encodes a short-chain dehydrogenase/reductase with 3-oxo-Delta4,5-steroid 5beta-reductase activity in Arabidopsis thaliana L. | 2009 Apr |
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Measurement of ring A-reduced progesterone metabolites by enzyme-linked immunoassay with colorimetric detection: baseline levels of six metabolites, including pregnanolone, in male rat plasma. | 2009 Feb 1 |
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30154
Created by
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5β-Dihydroprogesterone
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m9116
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admin on Sat Dec 16 10:08:16 GMT 2023 , Edited by admin on Sat Dec 16 10:08:16 GMT 2023
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128-23-4
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DB07557
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82868
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DTXSID00878589
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105J2Q45A0
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92745
Created by
admin on Sat Dec 16 10:08:16 GMT 2023 , Edited by admin on Sat Dec 16 10:08:16 GMT 2023
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SUBSTANCE RECORD