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Details

Stereochemistry ACHIRAL
Molecular Formula C4H8N2O3
Molecular Weight 132.1179
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIGLYCINE

SMILES

NCC(=O)NCC(O)=O

InChI

InChIKey=YMAWOPBAYDPSLA-UHFFFAOYSA-N
InChI=1S/C4H8N2O3/c5-1-3(7)6-2-4(8)9/h1-2,5H2,(H,6,7)(H,8,9)

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Metabolism of tetraglycine in isolated non-filtering rat kidneys.
2002
Direct dynamics study of N-protonated diglycine surface-induced dissociation. Influence of collision energy.
2003 Dec
A novel molecular ladder structure of Cu(II)-Ba(II) coordination polymer exhibiting ferromagnetic coupling.
2003 Dec 7
Molecular recognition in the gas phase ligand switching reactions of the proton bound dimer of sarcosine and glycylglycine.
2003 Feb 21
Specificity of the action of lysoamidase on Staphylococcus aureus 209P cell walls.
2003 Jul
[Analysis of the growth system of Candida albicans in a host and the development of new antifungal material].
2003 Jul
Redox modulation of NF-kappaB nuclear translocation and DNA binding in metastatic melanoma. The role of endogenous and gamma-glutamyl transferase-dependent oxidative stress.
2003 Jul-Aug
Metal-catalyzed hydroxylaminolysis of unactivated amide and peptide bonds.
2003 Mar 7
N[bond]C(alpha) bond dissociation energies and kinetics in amide and peptide radicals. Is the dissociation a non-ergodic process?
2003 May 14
Bis(glycylglycinium) oxalate at 100 K.
2003 Oct
Elimination of water from the carboxyl group of GlyGlyH+.
2003 Oct
Probing cathepsin K activity with a selective substrate spanning its active site.
2003 Oct 15
The bold legacy of Emil Fischer.
2003 Sep
Rotational resonance NMR: separation of dipolar coupling and zero quantum relaxation.
2003 Sep
A basis for SUMO protease specificity provided by analysis of human Senp2 and a Senp2-SUMO complex.
2004 Aug
Direct detection of biomolecules in a capillary electrophoresis-chemiluminescence detection system.
2004 Aug 1
A pH-stating mechanism in isolated wheat (Triticum aestivum) aleurone layers involves malic acid transport.
2004 Dec
On the mechanisms of oligopeptide reactions in solution and clay dispersion.
2004 Dec
Identification of sites of ubiquitination in proteins: a fourier transform ion cyclotron resonance mass spectrometry approach.
2004 Dec 1
The Gly-Gly linker region of the insect cytokine growth-blocking peptide is essential for activity.
2004 Dec 3
Hydrated metal(II) complexes of N-(6-amino-3,4-dihydro-3-methyl-5-nitroso-4-oxopyrimidin-2-yl) derivatives of glycine, glycylglycine, threonine, serine, valine and methionine: a monomeric complex and coordination polymers in one, two and three dimensions linked by hydrogen bonding.
2004 Feb
Additive transfer free energies of the peptide backbone unit that are independent of the model compound and the choice of concentration scale.
2004 Feb 10
Molecular modeling of dipeptide and its analogous systems with water.
2004 Jun
Synthesis of novel 3-pyridinecarbonitriles with amino acid function and their fluorescence properties.
2004 Mar
Inhibition of copper-catalyzed cysteine oxidation by nanomolar concentrations of iron salts.
2004 Mar 15
Part I: surface-enhanced Raman spectroscopy investigation of amino acids and their homodipeptides adsorbed on colloidal silver.
2004 May
Gas-phase H/D exchange of sodiated glycine oligomers with ND3: exchange kinetics do not reflect parent ion structures.
2004 May 26
Modification of the furanacryloyl-L-phenylalanylglycylglycine assay for determination of angiotensin-I-converting enzyme inhibitory activity.
2004 May 31
[Thermochemistry of dissolving glycine, glycyl-glycine, and diglycyl-glycine in a mixed water-dimethylsulfoxide solvent at 298.15 K].
2004 May-Jun
The Gly482Ser polymorphism in the peroxisome proliferator-activated receptor-gamma coactivator-1 gene is associated with hypertension in type 2 diabetic men.
2004 Nov
In vivo imaging of activated estrogen receptors in utero by estrogens and bisphenol A.
2004 Nov
Effect of dipeptides on the growth of Oenococcus oeni in synthetic medium deprived of amino acids.
2004 Nov
Catalytic transformations with copper-metalated diglycine conjugates.
2004 Nov 15
Binding behavior of aliphatic oligopeptides by bridged and metallobridged bis(beta-cyclodextrin)s bearing an oxamido bis(2-benzoic) carboxyl linker.
2004 Nov-Dec
Chlorination byproduct formation in the presence of humic acid, model nitrogenous organic compounds, ammonia, and bromide.
2004 Oct 1
Prominent role of gamma-glutamyl-transpeptidase on the growth of Helicobacter pylori.
2004 Oct 15
A generic basis for some simple light-operated mechanical molecular machines.
2004 Oct 6
Method for enhancing solubility of the expressed recombinant proteins in Escherichia coli.
2004 Sep
Enzyme hyperactivity in AOT water-in-oil microemulsions is induced by 'lone' sodium counterions in the water-pool.
2005
Tyrphostins reduce chemotherapy-induced intestinal injury in mice: assessment by a biochemical assay.
2005 Jan 31
Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription.
2005 Jul 27
Validation of a colorimetric assay for the in vitro screening of inhibitors of angiotensin-converting enzyme (ACE) from plant extracts.
2005 Jun
Ab initio-based exciton model of amide I vibrations in peptides: definition, conformational dependence, and transferability.
2005 Jun 8
New triorganotin(IV) derivatives of dipeptides as anti-inflammatory-antimicrobial agents.
2005 Mar
Solution structure of human SUMO-3 C47S and its binding surface for Ubc9.
2005 Mar 1
Photooxidation of diglycine in confined media. Application of the microreactor model for spin-correlated radical pairs in reverse micelles and water-in-oil microemulsions.
2005 Mar 29
Montanide ISA 720 vaccines: quality control of emulsions, stability of formulated antigens, and comparative immunogenicity of vaccine formulations.
2005 Mar 31
Industrial-scale production and purification of a heterologous protein in Lactococcus lactis using the nisin-controlled gene expression system NICE: the case of lysostaphin.
2005 May 27
Activity determination, kinetic analyses and isoenzyme identification of gamma glutamyltransferase in human neutrophils.
2005 May 31
Electrochemical determination of gamma-glutamyl transpeptidase activity and its application to a miniaturized analysis system.
2006 Jan 15
Patents

Patents

Name Type Language
DIGLYCINE
Common Name English
GLYCYLGLYCINE [MI]
Common Name English
GLYCYLGLYCINE
MI  
Systematic Name English
GLYCYL GLYCINE
Systematic Name English
DIPEPTIDE-15
INCI  
INCI  
Official Name English
DIPEPTIDE-15 [INCI]
Common Name English
DIGLYCINE [USP-RS]
Common Name English
NSC-49346
Code English
GLYCYL-GLYCINE
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C73539
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
Code System Code Type Description
DAILYMED
10525P22U0
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
SMS_ID
100000078742
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
EVMPD
SUB12510MIG
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
CHEBI
356445
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
RS_ITEM_NUM
1199308
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
ECHA (EC/EINECS)
209-127-8
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
RXCUI
1362904
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY RxNorm
NCI_THESAURUS
C81374
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
CHEBI
24786
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
MERCK INDEX
m5809
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY Merck Index
WIKIPEDIA
GLYCYLGLYCINE
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
EPA CompTox
DTXSID90862194
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
FDA UNII
10525P22U0
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
NSC
49346
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
CAS
556-50-3
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
PUBCHEM
11163
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY
CHEBI
17201
Created by admin on Fri Dec 15 16:19:31 GMT 2023 , Edited by admin on Fri Dec 15 16:19:31 GMT 2023
PRIMARY