ALLETHRIN

Discontinued

Details

Stereochemistry	MIXED
Molecular Formula	C19H26O3
Molecular Weight	302.4079
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

CC(C)=CC1C(C(=O)OC2CC(=O)C(CC=C)=C2C)C1(C)C

InChI

InChIKey=ZCVAOQKBXKSDMS-UHFFFAOYSA-N

InChI=1S/C19H26O3/c1-7-8-13-12(4)16(10-15(13)20)22-18(21)17-14(9-11(2)3)19(17,5)6/h7,9,14,16-17H,1,8,10H2,2-6H3

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary Target	Pharmacology	Potency
ATP-binding cassette sub-family G member 2	Inhibitor	42.5 µM [IC50]
Canalicular multispecific organic anion transporter 1	Inhibitor	48.2 µM [IC50]
Solute carrier organic anion transporter family member 1B1	Inhibitor	16.5 µM [IC50]
Solute carrier organic anion transporter family member 2B1	Activator	37.8 µM [EC50]
Multidrug and toxin extrusion protein 1	Inhibitor	50.2 µM [IC50]
Solute carrier family 22 member 1	Inhibitor	2.6 µM [IC50]

PubMed

Show entries

Title	Date	PubMed
Differential expression of muscarinic subtype mRNAs after exposure to neurotoxic pesticides.	1998 Nov-Dec	10192214
Mammalian voltage-gated calcium channels are potently blocked by the pyrethroid insecticide allethrin.	2004 Mar	14634047
Developmental neurotoxicity of pyrethroid insecticides: critical review and future research needs.	2005 Feb	15687048
Influence of pyrethroids and piperonyl butoxide on the Ca(2+)-ATPase activity of rat brain synaptosomes and leukocyte membranes.	2005 Feb	15652757
[Effect of S-bioallethrin on human lymphocyte].	2006 Mar	16546737

Showing 1 to 5 of 13 entries

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Patents

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Name

Type

Language

ALLETHRIN

Common Name

English

ALLETHROLONE ESTER OF CHRYSANTHEMUMMONOCARBOXYLIC ACID

Common Name

English

CYCLOPROPANECARBOXYLIC ACID, 2,2-DIMETHYL-3-(2-METHYLPROPENYL)-, ESTER WITH 2-ALLYL-4-HYDROXY-3-METHYL-2-CYCLOPENTEN-1-ONE

Common Name

English

ALLETHRIN [HSDB]

Common Name

English

ALLETHRIN I

Common Name

English

Showing 1 to 5 of 8 entries

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Show entries

Code System

Code

Type

Description

SMS_ID

100000077999

PRIMARY

CHEBI

34572

PRIMARY

CHEBI

39118

PRIMARY

EVMPD

SUB12789MIG

PRIMARY

RXCUI

513

PRIMARY

RxNorm

Showing 1 to 5 of 12 entries

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SUBSTANCE RECORD


					0X03II877M

ALLETHRIN