ALLETHRIN

Details

Stereochemistry	MIXED
Molecular Formula	C19H26O3
Molecular Weight	302.4079
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)=CC1C(C(=O)OC2CC(=O)C(CC=C)=C2C)C1(C)C

InChI

InChIKey=ZCVAOQKBXKSDMS-UHFFFAOYSA-N

InChI=1S/C19H26O3/c1-7-8-13-12(4)16(10-15(13)20)22-18(21)17-14(9-11(2)3)19(17,5)6/h7,9,14,16-17H,1,8,10H2,2-6H3

HIDE SMILES / InChI

Approval Year

Targets

Primary Target	Pharmacology	Potency
ATP-binding cassette sub-family G member 2 16 Target ID: CHEMBL5393 Sources: https://www.ncbi.nlm.nih.gov/pubmed/28099443	Inhibitor 8297	42.5 µM [IC50]
Canalicular multispecific organic anion transporter 1 21 Target ID: CHEMBL5748 Sources: https://www.ncbi.nlm.nih.gov/pubmed/28099443	Inhibitor 8297	48.2 µM [IC50]
Solute carrier organic anion transporter family member 1B1 32 Target ID: CHEMBL1697668 Sources: https://www.ncbi.nlm.nih.gov/pubmed/28099443	Inhibitor 8297	16.5 µM [IC50]
Solute carrier organic anion transporter family member 2B1 2 Target ID: CHEMBL1743124 Sources: https://www.ncbi.nlm.nih.gov/pubmed/28099443	Activator 1430	37.8 µM [EC50]
Multidrug and toxin extrusion protein 1 3 Target ID: CHEMBL1743126 Sources: https://www.ncbi.nlm.nih.gov/pubmed/28099443	Inhibitor 8297	50.2 µM [IC50]
Solute carrier family 22 member 1 18 Target ID: CHEMBL5685 Sources: https://www.ncbi.nlm.nih.gov/pubmed/28099443	Inhibitor 8297	2.6 µM [IC50]

PubMed

Title	Date	PubMed
Bioallethrin causes permanent changes in behavioural and muscarinic acetylcholine receptor variables in adult mice exposed neonatally to DDT.	1995 Jul 1	7589230
In vitro effects of the pyrethroid S-bioallethrin on lymphocytes and basophils from atopic and nonatopic subjects.	1998 Nov	9860237
Multiresidue method using SPME for the determination of various pesticides with different volatility in confined atmospheres.	2004 Jun	15085315
Ultra low volume aerosol application of deltacide (deltamethrin 0.5% w/v, S-bioallethrin 0.71% w/v & piperonyl butoxide 8.9% w/v) against mosquitoes.	2006 Jan	16567869
Maternal hair--an appropriate matrix for detecting maternal exposure to pesticides during pregnancy.	2006 Jul	16584725
[Effect of S-bioallethrin on human lymphocyte].	2006 Mar	16546737
The effects of combined exposure to the pyrethroids deltamethrin and S-bioallethrin on hippocampal inhibition and skeletal muscle hyperexcitability in rats.	2006 Oct 15	16875707
Enzyme-linked immunosorbent assay (ELISA) and sol-gel-based immunoaffinity purification (IAP) of the pyrethroid bioallethrin in food and environmental samples.	2006 Sep 6	16939301
Treatment of rabbit cheyletiellosis with selamectin or ivermectin: a retrospective case study.	2008 Jan 2	18171479
Divergent actions of the pyrethroid insecticides S-bioallethrin, tefluthrin, and deltamethrin on rat Na(v)1.6 sodium channels.	2010 Sep 15	20624410
Environmental impact on vascular development predicted by high-throughput screening.	2011 Nov	21788198
Antiplasmodial and antitrypanosomal activity of pyrethrins and pyrethroids.	2011 Sep 14	21786822
Effect of continuous inhalation of allethrin-based mosquito coil smoke in the male reproductive tract of rats.	2012 Feb	22356257
Differential state-dependent modification of inactivation-deficient Nav1.6 sodium channels by the pyrethroid insecticides S-bioallethrin, tefluthrin and deltamethrin.	2012 Jun	22465659

Patents

Name

Type

Language

ALLETHRIN

Common Name

English

ALLETHROLONE ESTER OF CHRYSANTHEMUMMONOCARBOXYLIC ACID

Common Name

English

CYCLOPROPANECARBOXYLIC ACID, 2,2-DIMETHYL-3-(2-METHYLPROPENYL)-, ESTER WITH 2-ALLYL-4-HYDROXY-3-METHYL-2-CYCLOPENTEN-1-ONE

Common Name

English

ALLETHRIN [HSDB]

Common Name

English

ALLETHRIN I

Common Name

English

PYNAMIN

Brand Name

English

2,2-DIMETHYL-3-(2-METHYL-1-PROPENYL)CYCLOPROPANECARBOXYLIC ACID 2-METHYL-4-OXO-3-(2-PROPENYL)-2-CYCLOPENTEN-1-YL ESTER

Systematic Name

English

ALLETHRIN I [MI]

Common Name

English

Code System Code Type Description

SMS_ID

100000077999