Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C2H4O3 |
| Molecular Weight | 76.0514 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OCC(O)=O
InChI
InChIKey=AEMRFAOFKBGASW-UHFFFAOYSA-N
InChI=1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)
SODIUM GLYCOLATE, a sodium salt of carboxymethyl ether, is used as a pharmaceutical grade dissolution excipient for solid dosage forms. It absorbs water rapidly, resulting in swelling which leads to the rapid disintegration of tablets and capsules. Without a disintegrant, these may not dissolve appropriately and may effect the amount of active ingredient absorbed, thereby decreasing effectiveness.
Approval Year
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Preventing | CLEAR CELL SALICYLIC CLARIFYING TONIC Approved UsePrevention and treatment of Acne and acne-prone skin. A salicylic/glycolic acid skin clarifying removes excess surface oil. A blend of anti-oxidants leaves skin fresh and shine-free. Launch Date2009 |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Intravenous nedaplatin and intraarterial cisplatin with transcatheter arterial embolization for patients with locally advanced uterine cervical cancer. | 2001 |
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| Ethylene glycol toxicity: the role of serum glycolic acid in hemodialysis. | 2001 |
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| An easy screening method for fungi producing ochratoxin A in pure culture. | 2001 Dec 30 |
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| [Small cell carcinoma of the urinary bladder: a case report]. | 2001 Oct |
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| Multiple sources of sodium starch glycolate, NF: evaluation of functional equivalence and development of standard performance tests. | 2002 |
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| Fast- and slow-release tablets for oral administration of flavonoids: rutin and quercetin. | 2002 Apr |
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| Global expression profiling of acetate-grown Escherichia coli. | 2002 Apr 12 |
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| Identification of a set of genes involved in the formation of the substrate for the incorporation of the unusual "glycolate" chain extension unit in ansamitocin biosynthesis. | 2002 Apr 24 |
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| [A case of advanced esophageal cancer with multiple lymph node metastases successfully treated with induction chemotherapy consisting of nedaplatin and 5-FU followed by chemoradiotherapy]. | 2002 Aug |
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| Potential mechanisms of marked hyperoxaluria not due to primary hyperoxaluria I or II. | 2002 Aug |
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| Preclinical combination chemotherapy of nedaplatin with gemcitabine against gemcitabine-refractory human lung cancer. | 2002 Aug 8 |
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| Phase I study of combination chemotherapy with 5-fluorouracil (5-FU) and nedaplatin (NDP): adverse effects and eecommended dose of NDP administered after 5-FU. | 2002 Dec |
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| Insights into substrate binding and catalytic mechanism of human tyrosyl-DNA phosphodiesterase (Tdp1) from vanadate and tungstate-inhibited structures. | 2002 Dec 13 |
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| [Current and future state of chemoradiotherapy for head and neck cancer]. | 2002 Feb |
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| [Cloning and expression of spinach glycolate oxidase in Escherichia coli]. | 2002 Jan |
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| Development of amperometric biosensors for the determination of glycolic acid in real samples. | 2002 Jan 1 |
|
| Transport of L-Lactate, D-Lactate, and glycolate by the LldP and GlcA membrane carriers of Escherichia coli. | 2002 Jan 18 |
|
| An aldol-based approach to the synthesis of the antibiotic anisomycin. | 2002 Jan 24 |
|
| Proteomic analysis of leaf peroxisomal proteins in greening cotyledons of Arabidopsis thaliana. | 2002 Jul |
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| Epithelial ovarian cancer: second and third line chemotherapy (review). | 2002 Jul |
|
| Structure of the complex of heptakis(2,6-di-O-methyl)-beta-cyclodextrin with (2,4-dichlorophenoxy)acetic acid. | 2002 Jul 16 |
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| Conversion of phosphoglycolate to phosphate termini on 3' overhangs of DNA double strand breaks by the human tyrosyl-DNA phosphodiesterase hTdp1. | 2002 Jul 26 |
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| Oxygen exchange in relation to carbon assimilation in water-stressed leaves during photosynthesis. | 2002 Jun |
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| Drought and oxidative load in the leaves of C3 plants: a predominant role for photorespiration? | 2002 Jun |
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| [Chemotherapy by superselective intraarterial infusion of nedaplatin combined with radiotherapy for oral cancer]. | 2002 Jun |
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| Primary hyperoxaluria: a rare but important cause of nephrolithiasis. | 2002 Jun |
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| Particular aspects of platinum compounds used at present in cancer treatment. | 2002 Jun |
|
| Chemical characterisation of sodium starch glycolate particles. | 2002 Jun 20 |
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| Purification and characterization of malate synthase from the glucose-grown wood-rotting basidiomycete Fomitopsis palustris. | 2002 Mar |
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| An inherited metabolic disorder presenting as ethylene glycol intoxication in a young adult. | 2002 Mar |
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| [Combined preoperative therapy for oral cancer with nedaplatin and radiation]. | 2002 Mar |
|
| [Combination chemotherapy with nedaplatin (CDGP) and 5-FU for oral cancer]. | 2002 Mar |
|
| Glycine oxidase from Bacillus subtilis. Characterization of a new flavoprotein. | 2002 Mar 1 |
|
| [Chemoradiation therapy for esophageal cancer]. | 2002 May |
|
| Synthesis of a novel class of polyhydroxyalkanoates in Arabidopsis peroxisomes, and their use in monitoring short-chain-length intermediates of beta-oxidation. | 2002 May |
|
| Sensitive and real-time determination of H2O2 release from intact peroxisomes. | 2002 May 1 |
|
| Asymmetric total synthesis of (-)-laulimalide: exploiting the asymmetric glycolate alkylation reaction. | 2002 May 29 |
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| "Inverse sodium hydride": a crystalline salt that contains H(+) and Na(-). | 2002 May 29 |
|
| [Combination chemotherapy of paclitaxel followed by nedaplatin for human ovarian cancer]. | 2002 Nov |
|
| Metabolic shifts in hypersaline microbial mats upon addition of organic substrates. | 2002 Nov |
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| Genetic analysis--a diagnostic tool for primary hyperoxaluria type I. | 2002 Nov |
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| The combined effect of drought stress and heat shock on gene expression in tobacco. | 2002 Nov |
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| Irinotecan plus cisplatin has substantial antitumor effect as salvage chemotherapy against germ cell tumors. | 2002 Nov 1 |
|
| Carbon exchange in hot alkaline degradation of glucose. | 2002 Nov 29 |
|
| [Clinical study of the combination of small amount of nedaplatin (CDGP)/5-FU with radiation for the treatment of esophageal cancer]. | 2002 Oct |
|
| Powder compaction properties of sodium starch glycolate disintegrants. | 2002 Sep |
|
| Influence of excipients, drugs, and osmotic agent in the inner core on the time-controlled disintegration of compression-coated ethylcellulose tablets. | 2002 Sep |
|
| A formula for predicting optimal dosage of nedaplatin based on renal function in adult cancer patients. | 2002 Sep |
|
| Repeated arthralgia associated with granulocyte colony stimulating factor administration. | 2002 Sep |
|
| Irinotecan in patients with relapsed or cisplatin-refractory germ cell cancer: a phase II study of the German Testicular Cancer Study Group. | 2002 Sep 23 |
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2395-2
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73883-1
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25106-6
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55864-3
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13751-3
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55865-0
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54286-0
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55863-5
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20831-4
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2396-0
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73882-3
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FDA ORPHAN DRUG |
872422
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EPA PESTICIDE CODE |
101
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78749-9
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26682-5
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42502-5
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757
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166
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DB03085
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SUB23402
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C45678
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CONCEPT | Industrial Aid | ||
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4645
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29805
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DTXSID0025363
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79-14-1
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Glycolic Acid
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100000088717
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70603
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ALTERNATIVE | |||
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0WT12SX38S
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17497
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587318
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201-180-5
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C83737
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5227
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m5804
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0WT12SX38S
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GLYCOLIC ACID
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ACTIVE MOIETY
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