| Stereochemistry | RACEMIC |
| Molecular Formula | C13H14N2O2 |
| Molecular Weight | 230.2625 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C[C@H]1N[C@@H](CC2=C1NC3=CC=CC=C23)C(O)=O
InChI
InChIKey=ZUPHXNBLQCSEIA-HQJQHLMTSA-N
InChI=1S/C13H14N2O2/c1-7-12-9(6-11(14-7)13(16)17)8-4-2-3-5-10(8)15-12/h2-5,7,11,14-15H,6H2,1H3,(H,16,17)/t7-,11+/m1/s1
(1R,3S)-1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (MTCA) is a β-carboline indole alkaloid naturally occurring in plants, foods, insects, and endogenously in mammals and humans. It exerts antioxidant and antithrombotic properties. MTCA is thought to be a possible causative substance of eosinophilia-myalgia syndrome associated with ingestion of L-tryptophan.
CNS Activity
Originator
Approval Year
PubMed
Patents
Sample Use Guides
rats: single oral dose 1.6 mg/kg or 10 mg/kg, chronic treatment with a 10 mg/kg dose for 6 weeks.
mice: 10-50 uM (iv)
Route of Administration:
Oral
