4-DIMETHYLAMINOPHENOL HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H11NO.ClH
Molecular Weight	173.64
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 4-DIMETHYLAMINOPHENOL HYDROCHLORIDE

Structure Search

SMILES

Cl.CN(C)C1=CC=C(O)C=C1

InChI

InChIKey=FGBQWWREKHAJIX-UHFFFAOYSA-N

InChI=1S/C8H11NO.ClH/c1-9(2)7-3-5-8(10)6-4-7;/h3-6,10H,1-2H3;1H

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/23111938 | https://www.ncbi.nlm.nih.gov/pubmed/8956097

4-dimethylaminophenol (or DMAP) is an effective intramuscular antidote for acute cyanide poisoning that works as a methemoglobin former.

Approval Year

PubMed

Title	Date	PubMed
Glutathione-dependent reduction of arsenate in human erythrocytes--a process independent of purine nucleoside phosphorylase.	2004 Dec	15470234
Determination of 4-dimethylaminophenol concentrations in dog blood using LC-ESI/MS/MS combined with precolumn derivatization.	2008 Dec 1	18993119

Sample Use Guides

In Vivo Use Guide

dimethylaminophenol (DMAP) is able to prevent the lethal effect of cyanide following intramuscular injections in dose sufficient to induce 20% methemoglobin (DMAP = 2 mg kg-1).

Route of Administration: Intramuscular

Name

Type

Language

4-DIMETHYLAMINOPHENOL HYDROCHLORIDE

Systematic Name

English

4-(Dimethylamino)phenol hydrochloride [WHO-DD]

Common Name

English

4-DIMETHYLAMINOPHENOL HYDROCHLORIDE [MART.]

Common Name

English

PHENOL, P-(DIMETHYLAMINO)-, HYDROCHLORIDE

Common Name

English

PHENOL, 4-(DIMETHYLAMINO)-, HYDROCHLORIDE

Systematic Name

English

PHENOL, 4-(DIMETHYLAMINO)-, HYDROCHLORIDE (1:1)

Systematic Name

English

Code System Code Type Description

RXCUI

236930