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Details

Stereochemistry ABSOLUTE
Molecular Formula C16H24N2O3
Molecular Weight 292.3734
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CARTEOLOL, (S)-

SMILES

CC(C)(C)NC[C@H](O)COC1=CC=CC2=C1CCC(=O)N2

InChI

InChIKey=LWAFSWPYPHEXKX-NSHDSACASA-N
InChI=1S/C16H24N2O3/c1-16(2,3)17-9-11(19)10-21-14-6-4-5-13-12(14)7-8-15(20)18-13/h4-6,11,17,19H,7-10H2,1-3H3,(H,18,20)/t11-/m0/s1

HIDE SMILES / InChI
(S)-Carteolol is an enantiomer of the racemic drug carteolol, that is used to treat glaucoma. (S) isomer is a partial agonist with the high affinity to the beta-adrenoceptors. It was shown, that in the treatment of glaucoma, the therapeutic advantage of the R(+)-isomers is similar to the S(-)-isomers and there is no stereo-selectivity between the two enantiomers.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Comparison of interactions of R-(+)- and S-(-)-isomers of beta-adrenergic partial agonists, befunolol and carteolol, with high affinity site of beta-adrenoceptors in isolated rabbit ciliary body and guinea-pig taenia caeci.
1991 Jul
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Name Type Language
CARTEOLOL, (S)-
Common Name English
(-)-CARTEOLOL
Common Name English
2(1H)-QUINOLINONE, 5-((2S)-3-((1,1-DIMETHYLETHYL)AMINO)-2-HYDROXYPROPOXY)-3,4-DIHYDRO-
Systematic Name English
Code System Code Type Description
FDA UNII
0PE570TA5N
Created by admin on Sat Dec 16 10:56:59 GMT 2023 , Edited by admin on Sat Dec 16 10:56:59 GMT 2023
PRIMARY
PUBCHEM
6604410
Created by admin on Sat Dec 16 10:56:59 GMT 2023 , Edited by admin on Sat Dec 16 10:56:59 GMT 2023
PRIMARY
CAS
81102-77-4
Created by admin on Sat Dec 16 10:56:59 GMT 2023 , Edited by admin on Sat Dec 16 10:56:59 GMT 2023
PRIMARY