U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry RACEMIC
Molecular Formula C21H26F3N5
Molecular Weight 405.4598
Optical Activity ( + / - )
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LORPIPRAZOLE

SMILES

[H][C@]12CCC[C@@]1([H])C3=NN=C(CCN4CCN(CC4)C5=CC=CC(=C5)C(F)(F)F)N3C2

InChI

InChIKey=BNRMWKUVWLKDQJ-CRAIPNDOSA-N
InChI=1S/C21H26F3N5/c22-21(23,24)16-4-2-5-17(13-16)28-11-9-27(10-12-28)8-7-19-25-26-20-18-6-1-3-15(18)14-29(19)20/h2,4-5,13,15,18H,1,3,6-12,14H2/t15-,18-/m1/s1

HIDE SMILES / InChI
Lorpiprazole (brand name Normarex) is a marketed anxiolytic drug of the phenylpiperazine group. It has been described as a serotonin antagonist and reuptake inhibitor (SARI) in the same group as trazodone, nefazodone, and etoperidone.

Approval Year

PubMed

PubMed

TitleDatePubMed
Rediscovering trazodone for the treatment of major depressive disorder.
2012 Dec
Name Type Language
LORPIPRAZOLE
INN  
INN  
Official Name English
(±)-CIS-5,5A,6,7,8,8A-HEXAHYDRO-3-(2-(4-(.ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-M-TOLYL)-1-PIPERAZINYL)ETHYL)CYCLOPENTA(3,4)PYRROLO(2,1-C)-S-TRIAZOLE
Common Name English
lorpiprazole [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29710
Created by admin on Fri Dec 15 16:11:30 GMT 2023 , Edited by admin on Fri Dec 15 16:11:30 GMT 2023
Code System Code Type Description
PUBCHEM
3045380
Created by admin on Fri Dec 15 16:11:30 GMT 2023 , Edited by admin on Fri Dec 15 16:11:30 GMT 2023
PRIMARY
CAS
108785-69-9
Created by admin on Fri Dec 15 16:11:30 GMT 2023 , Edited by admin on Fri Dec 15 16:11:30 GMT 2023
PRIMARY
EPA CompTox
DTXSID30883181
Created by admin on Fri Dec 15 16:11:30 GMT 2023 , Edited by admin on Fri Dec 15 16:11:30 GMT 2023
PRIMARY
INN
6347
Created by admin on Fri Dec 15 16:11:30 GMT 2023 , Edited by admin on Fri Dec 15 16:11:30 GMT 2023
PRIMARY
DRUG BANK
DB09195
Created by admin on Fri Dec 15 16:11:30 GMT 2023 , Edited by admin on Fri Dec 15 16:11:30 GMT 2023
PRIMARY
EVMPD
SUB08590MIG
Created by admin on Fri Dec 15 16:11:30 GMT 2023 , Edited by admin on Fri Dec 15 16:11:30 GMT 2023
PRIMARY
ChEMBL
CHEMBL2218904
Created by admin on Fri Dec 15 16:11:30 GMT 2023 , Edited by admin on Fri Dec 15 16:11:30 GMT 2023
PRIMARY
SMS_ID
100000082034
Created by admin on Fri Dec 15 16:11:30 GMT 2023 , Edited by admin on Fri Dec 15 16:11:30 GMT 2023
PRIMARY
DRUG CENTRAL
5098
Created by admin on Fri Dec 15 16:11:30 GMT 2023 , Edited by admin on Fri Dec 15 16:11:30 GMT 2023
PRIMARY
WIKIPEDIA
Lorpiprazole
Created by admin on Fri Dec 15 16:11:30 GMT 2023 , Edited by admin on Fri Dec 15 16:11:30 GMT 2023
PRIMARY
FDA UNII
0M14O7T47Q
Created by admin on Fri Dec 15 16:11:30 GMT 2023 , Edited by admin on Fri Dec 15 16:11:30 GMT 2023
PRIMARY
NCI_THESAURUS
C81579
Created by admin on Fri Dec 15 16:11:30 GMT 2023 , Edited by admin on Fri Dec 15 16:11:30 GMT 2023
PRIMARY