LORPIPRAZOLE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C21H26F3N5
Molecular Weight	405.4598
Optical Activity	( + / - )
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of LORPIPRAZOLE

Structure Search

SMILES

[H][C@]12CCC[C@@]1([H])C3=NN=C(CCN4CCN(CC4)C5=CC=CC(=C5)C(F)(F)F)N3C2

InChI

InChIKey=BNRMWKUVWLKDQJ-CRAIPNDOSA-N

InChI=1S/C21H26F3N5/c22-21(23,24)16-4-2-5-17(13-16)28-11-9-27(10-12-28)8-7-19-25-26-20-18-6-1-3-15(18)14-29(19)20/h2,4-5,13,15,18H,1,3,6-12,14H2/t15-,18-/m1/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/23192413 | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 742, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ | https://alchetron.com/Lorpiprazole

Lorpiprazole (brand name Normarex) is a marketed anxiolytic drug of the phenylpiperazine group. It has been described as a serotonin antagonist and reuptake inhibitor (SARI) in the same group as trazodone, nefazodone, and etoperidone.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Rediscovering trazodone for the treatment of major depressive disorder.	2012 Dec	23192413

Name

Type

Language

LORPIPRAZOLE

Official Name

English

(±)-CIS-5,5A,6,7,8,8A-HEXAHYDRO-3-(2-(4-(.ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-M-TOLYL)-1-PIPERAZINYL)ETHYL)CYCLOPENTA(3,4)PYRROLO(2,1-C)-S-TRIAZOLE

Common Name

English

lorpiprazole [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29710

Created by admin on Fri Dec 15 16:11:30 GMT 2023 , Edited by admin on Fri Dec 15 16:11:30 GMT 2023

Code System Code Type Description

PUBCHEM

3045380

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CAS

108785-69-9

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EPA CompTox

DTXSID30883181

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INN

6347

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DRUG BANK

DB09195

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EVMPD

SUB08590MIG

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ChEMBL

CHEMBL2218904

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SMS_ID

100000082034

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DRUG CENTRAL

5098

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WIKIPEDIA

Lorpiprazole

Created by admin on Fri Dec 15 16:11:30 GMT 2023 , Edited by admin on Fri Dec 15 16:11:30 GMT 2023

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FDA UNII

0M14O7T47Q

Created by admin on Fri Dec 15 16:11:30 GMT 2023 , Edited by admin on Fri Dec 15 16:11:30 GMT 2023

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NCI_THESAURUS

C81579

Created by admin on Fri Dec 15 16:11:30 GMT 2023 , Edited by admin on Fri Dec 15 16:11:30 GMT 2023

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ACTIVE MOIETY


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