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Details

Stereochemistry ACHIRAL
Molecular Formula C14H12N2O4S
Molecular Weight 304.321
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TIOXACIN

SMILES

CCN1C=C(C(O)=O)C(=O)C2=C3SC(=O)N(C)C3=CC=C12

InChI

InChIKey=VUUPJGYIOAVFAN-UHFFFAOYSA-N
InChI=1S/C14H12N2O4S/c1-3-16-6-7(13(18)19)11(17)10-8(16)4-5-9-12(10)21-14(20)15(9)2/h4-6H,3H2,1-2H3,(H,18,19)

HIDE SMILES / InChI
Tioxacin is a bactericide agent. Tioxacin gives a soluble complex with aliphatic amines and had the highest activities against G(+) and G (-) bacteria, including Escherichia coli resistant to nalidixic acid and Pseudomonas aeruginosa from 98 acids of this type. Absorption studies in dogs suggested that the amine complex may have a great utility as a rapid dissolving form of tioxacin in oral administration.

Approval Year

PubMed

PubMed

TitleDatePubMed
[Soluble complex formation of 6-ethyl-2,3,6,9-tetrahydro-3-methyl-2,9-dioxothiazolo-[5,4-f]quinoline-8-carboxylic acid (tioxacin) with aliphatic amines (author's transl)].
1979 May
Name Type Language
TIOXACIN
INN  
INN  
Official Name English
tioxacin [INN]
Common Name English
TIOXACIN [JAN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C795
Created by admin on Fri Dec 15 15:30:42 GMT 2023 , Edited by admin on Fri Dec 15 15:30:42 GMT 2023
Code System Code Type Description
INN
3838
Created by admin on Fri Dec 15 15:30:42 GMT 2023 , Edited by admin on Fri Dec 15 15:30:42 GMT 2023
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EVMPD
SUB11096MIG
Created by admin on Fri Dec 15 15:30:42 GMT 2023 , Edited by admin on Fri Dec 15 15:30:42 GMT 2023
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FDA UNII
0K40CNM74K
Created by admin on Fri Dec 15 15:30:42 GMT 2023 , Edited by admin on Fri Dec 15 15:30:42 GMT 2023
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ChEMBL
CHEMBL2105419
Created by admin on Fri Dec 15 15:30:42 GMT 2023 , Edited by admin on Fri Dec 15 15:30:42 GMT 2023
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EPA CompTox
DTXSID90188523
Created by admin on Fri Dec 15 15:30:42 GMT 2023 , Edited by admin on Fri Dec 15 15:30:42 GMT 2023
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NCI_THESAURUS
C76924
Created by admin on Fri Dec 15 15:30:42 GMT 2023 , Edited by admin on Fri Dec 15 15:30:42 GMT 2023
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PUBCHEM
65788
Created by admin on Fri Dec 15 15:30:42 GMT 2023 , Edited by admin on Fri Dec 15 15:30:42 GMT 2023
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SMS_ID
100000077256
Created by admin on Fri Dec 15 15:30:42 GMT 2023 , Edited by admin on Fri Dec 15 15:30:42 GMT 2023
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MESH
C012064
Created by admin on Fri Dec 15 15:30:42 GMT 2023 , Edited by admin on Fri Dec 15 15:30:42 GMT 2023
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CAS
34976-39-1
Created by admin on Fri Dec 15 15:30:42 GMT 2023 , Edited by admin on Fri Dec 15 15:30:42 GMT 2023
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