U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C20H21FN6O
Molecular Weight 380.4187
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SELITRECTINIB

SMILES

C[C@@H]1CCC2=NC=C(F)C=C2[C@H]3CCCN3C4=NC5=C(C=NN5C=C4)C(=O)N1

InChI

InChIKey=OEBIHOVSAMBXIB-SJKOYZFVSA-N
InChI=1S/C20H21FN6O/c1-12-4-5-16-14(9-13(21)10-22-16)17-3-2-7-26(17)18-6-8-27-19(25-18)15(11-23-27)20(28)24-12/h6,8-12,17H,2-5,7H2,1H3,(H,24,28)/t12-,17-/m1/s1

HIDE SMILES / InChI

Approval Year

Name Type Language
SELITRECTINIB
INN  
Official Name English
12H-5,7-ETHENOPYRAZOLO(3,4-D)PYRIDO(2,3-K)PYRROLO(2,1-M)(1,3,7)TRIAZACYCLOTRIDECIN-12-ONE, 5-FLUORO-1,2,3,3A,8,9,10,11-OCTAHYDRO-10-METHYL-, (3AR,10R)-
Systematic Name English
(22R,6R)-35-FLUORO-6-METHYL-1(5,3)-PYRAZOLO(1,5-A)PYRIMIDINA-3(3,2)-PYRIDINA-2(1,2)-PYRROLIDINACYCLOOCTAPHAN-8-ONE
Common Name English
Selitrectinib [WHO-DD]
Common Name English
LOXO-195
Code English
selitrectinib [INN]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 651318
Created by admin on Sat Dec 16 12:50:27 GMT 2023 , Edited by admin on Sat Dec 16 12:50:27 GMT 2023
Code System Code Type Description
PUBCHEM
129103609
Created by admin on Sat Dec 16 12:50:27 GMT 2023 , Edited by admin on Sat Dec 16 12:50:27 GMT 2023
PRIMARY
INN
10968
Created by admin on Sat Dec 16 12:50:27 GMT 2023 , Edited by admin on Sat Dec 16 12:50:27 GMT 2023
PRIMARY
SMS_ID
300000005953
Created by admin on Sat Dec 16 12:50:27 GMT 2023 , Edited by admin on Sat Dec 16 12:50:27 GMT 2023
PRIMARY
CAS
1350884-56-8
Created by admin on Sat Dec 16 12:50:27 GMT 2023 , Edited by admin on Sat Dec 16 12:50:27 GMT 2023
NON-SPECIFIC STEREOCHEMISTRY
NCI_THESAURUS
C138160
Created by admin on Sat Dec 16 12:50:27 GMT 2023 , Edited by admin on Sat Dec 16 12:50:27 GMT 2023
PRIMARY
CAS
2097002-61-2
Created by admin on Sat Dec 16 12:50:27 GMT 2023 , Edited by admin on Sat Dec 16 12:50:27 GMT 2023
PRIMARY
DRUG BANK
DB14896
Created by admin on Sat Dec 16 12:50:27 GMT 2023 , Edited by admin on Sat Dec 16 12:50:27 GMT 2023
PRIMARY
FDA UNII
0J45910S3X
Created by admin on Sat Dec 16 12:50:27 GMT 2023 , Edited by admin on Sat Dec 16 12:50:27 GMT 2023
PRIMARY