MAGNESITE

Details

Stereochemistry	ACHIRAL
Molecular Formula	CO3.Mg
Molecular Weight	84.3139
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Mg++].[O-]C([O-])=O

InChI

InChIKey=ZLNQQNXFFQJAID-UHFFFAOYSA-L

InChI=1S/CH2O3.Mg/c2-1(3)4;/h(H2,2,3,4);/q;+2/p-2

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Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/8770963http://www.dancingwithwater.com/articles/magnesium-bicarbonate-water-the-importance-of-bicarbonates-and-magnesium/
Curator's Comment: description was created based on several sources, including: https://www.ncbi.nlm.nih.gov/pubmed/24754016 / http://www.uniquewater.com.au/

Magnesium bicarbonate supplemented water provides a source of orally available magnesium. A one-month intake of mineral water rich in calcium, magnesium bicarbonate, and sulfate decreased cholesterol and LDL levels but not TG or HDL levels in dyslipidemic adults. Optimal hydration with Unique Water (Magnesium bicarbonate liquid) over three months may significantly increase blood magnesium levels, may significantly stabilise blood parathyroid hormone levels and may significantly increase blood albumin protein levels.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
magnesium ion homeostasis 70 Target ID: GO:0010960 Sources: https://www.ncbi.nlm.nih.gov/pubmed/9070556	Modulator 828
Magnesium-bicarbonate ATPase 2 Target ID: Magnesium-bicarbonate ATPase Sources: https://www.ncbi.nlm.nih.gov/pubmed/162573	Activator 1430

Conditions

Condition	Modality	Highest Phase	Product
Mitral valve prolapse syndrome 2 Sources: https://www.ncbi.nlm.nih.gov/pubmed/9070556	Palliative	Phase II 1132	Unknown Approved Use Unknown
Paroxysmal supraventricular tachycardia 7 Sources: https://www.ncbi.nlm.nih.gov/pubmed/7483616	Preventing	Phase II 1132	Unknown Approved Use Unknown
Hyperphosphatemia 30 Sources: https://www.ncbi.nlm.nih.gov/pubmed/21812357	Primary	Phase II 1132	Unknown Approved Use Unknown
Dyslipidemia 30 Sources: https://www.ncbi.nlm.nih.gov/pubmed/20579398	Primary	Not Provided 504	Unique Water Approved Use Unknown

PubMed

Title	Date	PubMed
Clinical symptoms of mitral valve prolapse are related to hypomagnesemia and attenuated by magnesium supplementation.	1997 Mar 15	9070556
A double-blind, placebo-controlled study of the short term effects of a spring water supplemented with magnesium bicarbonate on acid/base balance, bone metabolism and cardiovascular risk factors in postmenopausal women.	2010 Jun 28	20579398

Patents

Sample Use Guides

In Vivo Use Guide

3 x 0.6 mg during 3 months

Route of Administration: Oral

In Vitro Use Guide

Unknown

Name

Type

Language

MAGNESITE

Common Name

English

ANHYDROUS MAGNESIUM CARBONATE

Common Name

English

ANHYDROUS MAGNESIUM CARBONATE [MART.]

Common Name

English

Magnesium carbonate [WHO-DD]

Common Name

English

NSC-83511

Code

English

E-504(I)

Common Name

English

MAGNESITE (MG(CO3))

Common Name

English

INS NO.504(I)

Common Name

English

MAGNESIUM CARBONATE GOLD STAR

Common Name

English

MAGNESIUM CARBONATE ANHYDROUS

Common Name

English

INS-504(I)

Common Name

English

C.I. 77713

Code

English

Classification Tree Code System Code

JECFA EVALUATION

INS-504(I)