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Details

Stereochemistry ACHIRAL
Molecular Formula 2Na.O4Se.10H2O
Molecular Weight 369.09
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM SELENATE DECAHYDRATE

SMILES

O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].[O-][Se]([O-])(=O)=O

InChI

InChIKey=TYVNFQRMDPFYPC-UHFFFAOYSA-L
InChI=1S/2Na.H2O4Se.10H2O/c;;1-5(2,3)4;;;;;;;;;;/h;;(H2,1,2,3,4);10*1H2/q2*+1;;;;;;;;;;;/p-2

HIDE SMILES / InChI

Description
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/24323428 | https://www.ncbi.nlm.nih.gov/pubmed/26468123 | https://www.ncbi.nlm.nih.gov/pubmed/25485856

SELENATE ION is a compound containing an oxoanion with selenium in its highest oxidation state of VI. Selenates are analogous to sulfates and have similar chemistry, but unlike sulfate, selenate is a good oxidizer. Selenate is the form required by organisms that need selenium as a micronutrient. These organisms have the ability to acquire, metabolize and excrete selenium. The level at which selenium becomes toxic varies from species to species and is related to other environmental factors like pH and alkalinity that influence the concentration of selenite over selenate. Selenate and other forms of selenium are highest in areas where ancient seas have evaporated. These areas are enriched in selenium and over millennia, biologic adaptation has occurred.

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
Primary
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Effects of trace metal compounds on HIV-1 reverse transcriptase: an in vitro study.
1999 May
Bacterial respiration of arsenic and selenium.
1999 Oct
Patents

Patents

Sample Use Guides

200-400 µg selenium as selenate
Route of Administration: Oral
N2aSW cell viability was detected by the CCK-8 assay. Briefly, N2aSW cells (5X10^3 per well) exposed to sodium selenate at a set of concentrations (0.00001, 0.0001, 0.001, 0.01, 0.1, 1, 10 mmol/L in FBS-free medium) were grown in 96-well-plates for 24 h. 10% CCK-8 reagent was added to each well and the cells were incubated at 37°C for another 2 h. Cells without sodium selenate treatment were used as the control. The absorbance at 450 nm was measured with a reference wavelength of 650 nm by SpecTRA MAX 190 microplate reader (Molecular Devices, Sunnyvale, CA, USA). All experiments were performed in triplicates.
Name Type Language
SODIUM SELENATE DECAHYDRATE
MI  
Systematic Name English
DISODIUM SELENATE DECAHYDRATE
Systematic Name English
SODIUM SELENATE DECAHYDRATE [MI]
Common Name English
Code System Code Type Description
PUBCHEM
202320
Created by admin on Fri Dec 15 17:16:57 GMT 2023 , Edited by admin on Fri Dec 15 17:16:57 GMT 2023
PRIMARY
FDA UNII
0CJN4029EB
Created by admin on Fri Dec 15 17:16:57 GMT 2023 , Edited by admin on Fri Dec 15 17:16:57 GMT 2023
PRIMARY
CAS
10102-23-5
Created by admin on Fri Dec 15 17:16:57 GMT 2023 , Edited by admin on Fri Dec 15 17:16:57 GMT 2023
PRIMARY
MERCK INDEX
m10070
Created by admin on Fri Dec 15 17:16:57 GMT 2023 , Edited by admin on Fri Dec 15 17:16:57 GMT 2023
PRIMARY Merck Index
EPA CompTox
DTXSID50143673
Created by admin on Fri Dec 15 17:16:57 GMT 2023 , Edited by admin on Fri Dec 15 17:16:57 GMT 2023
PRIMARY