U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C24H24ClFN2O
Molecular Weight 410.912
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LINRODOSTAT

SMILES

[H][C@@]1(CC[C@]([H])(CC1)C2=CC=NC3=C2C=C(F)C=C3)[C@@H](C)C(=O)NC4=CC=C(Cl)C=C4

InChI

InChIKey=KRTIYQIPSAGSBP-ZACQAIPSSA-N
InChI=1S/C24H24ClFN2O/c1-15(24(29)28-20-9-6-18(25)7-10-20)16-2-4-17(5-3-16)21-12-13-27-23-11-8-19(26)14-22(21)23/h6-17H,2-5H2,1H3,(H,28,29)/t15-,16-,17+/m1/s1

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
1.1 nM [IC50]
Name Type Language
LINRODOSTAT
USAN   INN  
Official Name English
LINRODOSTAT [USAN]
Common Name English
F-001287
Code English
(2R)-N-(4-CHLOROPHENYL)-2-(4-(6-FLUORO-4-QUINOLYL)CYCLOHEXYL)PROPANAMIDE, CIS-
Systematic Name English
BMS-986205
Code English
CYCLOHEXANEACETAMIDE, N-(4-CHLOROPHENYL)-4-(6-FLUORO-4-QUINOLINYL)-.ALPHA.-METHYL-, CIS-(.ALPHA.R)-
Systematic Name English
Linrodostat [WHO-DD]
Common Name English
ONO7701
Code English
F001287
Code English
linrodostat [INN]
Common Name English
ONO-7701
Code English
Code System Code Type Description
DRUG BANK
DB14986
Created by admin on Sat Dec 16 18:08:07 GMT 2023 , Edited by admin on Sat Dec 16 18:08:07 GMT 2023
PRIMARY
FDA UNII
0A7729F42K
Created by admin on Sat Dec 16 18:08:07 GMT 2023 , Edited by admin on Sat Dec 16 18:08:07 GMT 2023
PRIMARY
PUBCHEM
121328278
Created by admin on Sat Dec 16 18:08:07 GMT 2023 , Edited by admin on Sat Dec 16 18:08:07 GMT 2023
PRIMARY
NCI_THESAURUS
C141135
Created by admin on Sat Dec 16 18:08:07 GMT 2023 , Edited by admin on Sat Dec 16 18:08:07 GMT 2023
PRIMARY
INN
10894
Created by admin on Sat Dec 16 18:08:07 GMT 2023 , Edited by admin on Sat Dec 16 18:08:07 GMT 2023
PRIMARY
CAS
1923833-60-6
Created by admin on Sat Dec 16 18:08:07 GMT 2023 , Edited by admin on Sat Dec 16 18:08:07 GMT 2023
PRIMARY
USAN
EF-138
Created by admin on Sat Dec 16 18:08:07 GMT 2023 , Edited by admin on Sat Dec 16 18:08:07 GMT 2023
PRIMARY
SMS_ID
100000183407
Created by admin on Sat Dec 16 18:08:07 GMT 2023 , Edited by admin on Sat Dec 16 18:08:07 GMT 2023
PRIMARY