Details
Stereochemistry | ACHIRAL |
Molecular Formula | C15H11ClN2O |
Molecular Weight | 270.714 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=NC2=CC=CC=C2C(=O)N1C3=C(Cl)C=CC=C3
InChI
InChIKey=SFITWQDBYUMAPS-UHFFFAOYSA-N
InChI=1S/C15H11ClN2O/c1-10-17-13-8-4-2-6-11(13)15(19)18(10)14-9-5-3-7-12(14)16/h2-9H,1H3
Mecloqualone is a quinazoline-class GABAergic and an analog of methaqualone. It acts as an agonist of the beta subtype of GABAa receptor and induces sedative, hypnotic and anxiolytic effects. Mecloqualone was marketed (mostly in france) under the names Nubrene and Casfen for the treatment of insomnia. Mecloqualone is no longer prescribed because of concerns about its potential for abuse and overdose. In the United States, it is registered as a Schedule-I non-narcotic controlled substance.
CNS Activity
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Approval Year
Targets
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Target ID: CHEMBL2109244 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
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Primary | Nubarene Approved UseMecloqualone was approved for treatment of insomnia in the 1960's. The potential for abuse lead to discontinuation and subsequent legal restrictions. |
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2572
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WIKIPEDIA |
Designer-drugs-Mecloqualone
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ACTIVE MOIETY