Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C3Cl2N3O3.Na |
| Molecular Weight | 219.946 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Na+].ClN1C(=O)[N-]C(=O)N(Cl)C1=O
InChI
InChIKey=MSFGZHUJTJBYFA-UHFFFAOYSA-M
InChI=1S/C3HCl2N3O3.Na/c4-7-1(9)6-2(10)8(5)3(7)11;/h(H,6,9,10);/q;+1/p-1
DescriptionCurator's Comment: description was created based on several sources, including:
http://www.preciseformulation.com/nadcc-tablets-general-applications.html | http://akvopedia.org/wiki/Chlorine_(NaDCC) | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b345ae6a-0b36-45c7-b31e-2a15508a2ef5 | https://www.ncbi.nlm.nih.gov/pubmed/20064989
Curator's Comment: description was created based on several sources, including:
http://www.preciseformulation.com/nadcc-tablets-general-applications.html | http://akvopedia.org/wiki/Chlorine_(NaDCC) | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b345ae6a-0b36-45c7-b31e-2a15508a2ef5 | https://www.ncbi.nlm.nih.gov/pubmed/20064989
Troclosene is chlorinated hydroxytriazine and it is used as a source of free available chlorine, in the form of hypochlorous acid, for the disinfection of water. It kills bacteria, bacterial spores, cysts, algae, fungi, protozoa and virus and are especially lethal to Entamoeba histolytica. Troclosene kills mastitis-causing organisms. It is now widely available for household water treatment. It does not prevent diarrhea but improved water quality.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Life threatening airway obstruction in a newborn following ingestion of sterilising tablet. | 2001 Nov |
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| [Sodium dichloroisocyanurate: a major disinfectant for drinking water]. | 2002 |
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| Germicidal activities of representatives of five different teat dip classes against three bovine mycoplasma species using a modified excised teat model. | 2002 Aug |
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| Reduction of mastitis caused by experimental challenge with Staphylococcus aureus and Streptococcus agalactiae by use of a quaternary ammonium and halogen-mixture teat dip. | 2002 Jan |
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| Preventing infection from reusable medical equipment: a systematic review. | 2002 Mar 27 |
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| Flow injection chemiluminescence determination of hydrazine by oxidation with chlorinated isocyanurates. | 2002 Oct 16 |
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| The effect of potassium permanganate and sodium dichloroisocyanurate on metacercariae of Fasciola gigantica. | 2003 Apr |
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| Determination of ammonia in beers by pervaporation flow injection analysis and spectrophotometric detection. | 2003 Aug 29 |
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| Flow-injection chemiluminescence determination of chlorinated isocyanuric acids. | 2003 Feb |
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| Sanichlor-induced atopic dermatitis and asthma in ophthalmologists. | 2003 Jan |
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| Determination of decimal reduction time (D value) of chemical agents used in hospitals for disinfection purposes. | 2003 Oct 17 |
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| Effects of different disinfection treatments on the natural microbiota of lettuce. | 2003 Sep |
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| [Bioactive effectiveness of selected disinfective agents on Gram-negative bacilli isolated from hospital environment]. | 2004 |
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| Resistance of spheroplasts and whole cells of Pseudomonas aeruginosa to bactericidal activity of various biocides: evidence of the membrane implication. | 2004 |
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| The effect of a range of disinfectants on the dimensional accuracy of some impression materials. | 2004 Dec |
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| Efficacy of three surface disinfectants for dental radiographic films and gloves. | 2004 Jul |
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| The effect of Perasafe and sodium dichloroisocyanurate (NaDCC) against spores of Clostridium difficile and Bacillus atrophaeus on stainless steel and polyvinyl chloride surfaces. | 2004 Jun |
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| Flow-injection determination of isoniazid using sodium dichloroisocyanurate- and trichloroisocyanuric acid-luminol chemiluminescence systems. | 2004 Jun |
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| Soft tissue dissolution capacity of currently used and potential endodontic irrigants. | 2004 Nov |
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| The effect of sterilization methods on the light transmission characteristics and structure of light-curing tips. | 2004 Sep |
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| Chlorine covers on living bacteria: the initial step in antimicrobial action of active chlorine compounds. | 2005 Apr |
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| Flow-injection potentiometric determination of triiodide by plasticized poly(vinyl chloride) membrane electrodes and its application to the determination of chlorine-containing disinfectants. | 2005 Mar 15 |
|
| [Study on the resistance of Escherichia coli O157:H7 to disinfectants in relationship with its plasmid pO157 and chromosome DNA]. | 2005 Nov |
|
| [Comparison on resistance of bacteriophages to sodium dichloroisocyanurate in laboratory]. | 2006 Jan |
|
| Sodium dichloroisocyanurate (NaDCC) tablets as an alternative to sodium hypochlorite for the routine treatment of drinking water at the household level. | 2006 Mar |
|
| Whole-genome analysis of the SHORT-ROOT developmental pathway in Arabidopsis. | 2006 May |
|
| Efficacy of hospital cleaning agents and germicides against epidemic Clostridium difficile strains. | 2007 Aug |
|
| Household water treatment using sodium dichloroisocyanurate (NaDCC) tablets: a randomized, controlled trial to assess microbiological effectiveness in Bangladesh. | 2007 Jan |
|
| Comparative sporicidal effects of disinfectants after release of a biological agent. | 2007 Jun |
|
| Analytical method for the quantitative determination of cyanuric acid as the degradation product of sodium dichloroisocyanurate in urine by liquid chromatography mass spectrometry. | 2007 Jun 15 |
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| Virucidal agents in the eve of manorapid synergy. | 2007 Sep 13 |
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| Tonometer disinfection practice in the United Kingdom: a national survey. | 2008 Aug |
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| Sporicidal activity of two disinfectants against Clostridium difficile spores. | 2008 Mar 13-26 |
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| Advantages of sodium hypochlorite or sodium dichloroisocyanurate disinfection for teats and bottles in newborn infants' feeding. | 2008 Mar-Apr |
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| UV-visible marker confirms that environmental persistence of Clostridium difficile spores in toilets of patients with C. difficile-associated diarrhea is associated with lack of compliance with cleaning protocol.e. | 2008 May 12 |
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| Use of sodium dichloroisocyanurate for floor disinfection. | 2009 Jul |
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| Disinfection of irreversible hydrocolloid impression material with chlorinated compounds. | 2009 Jun |
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| Effects of pH and oil-in-water emulsions on growth and physicochemical cell surface properties of Listeria monocytogenes: Impact on tolerance to the bactericidal activity of disinfectants. | 2009 Mar 31 |
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| A comparative study assaying commonly used sanitizers for antimicrobial activity against indicator bacteria and a Salmonella Typhimurium strain on fresh produce. | 2009 Nov |
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| [Specific antisepsis and environmental disinfection in preventing "Clostridium difficile associated diarrhea"]. | 2009 Nov-Dec |
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| Collection of indonaphthol blue on a membrane filter for the spectrophotometric determination of ammonia with 1-naphthol and dichloroisocyanurate. | 2010 |
|
| Disinfection efficacy of sodium dichloroisocyanurate (NADCC) against common food-borne intestinal protozoa. | 2010 Apr |
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| Improvements to water purification and sanitation infrastructure may reduce the diarrheal burden in a marginalized and flood prone population in remote Nicaragua. | 2010 Dec 8 |
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| Consumer exposure to biocides--identification of relevant sources and evaluation of possible health effects. | 2010 Feb 3 |
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| Sodium dichloroisocyanurate tablets for routine treatment of household drinking water in periurban Ghana: a randomized controlled trial. | 2010 Jan |
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| Disinfection by-product formation and mitigation strategies in point-of-use chlorination with sodium dichloroisocyanurate in Tanzania. | 2010 Jul |
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| Jasmonic acid and ethylene modulate local responses to wounding and simulated herbivory in Nicotiana attenuata leaves. | 2010 Jun |
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| Root canal irrigants. | 2010 Oct |
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| Field assessment of a novel household-based water filtration device: a randomised, placebo-controlled trial in the Democratic Republic of Congo. | 2010 Sep 10 |
|
| 1,1'-Azobis-1,2,3-triazole: a high-nitrogen compound with stable N8 structure and photochromism. | 2010 Sep 8 |
Patents
Sample Use Guides
Viral suspensions were prepared containing 10(4)-10(5) syncitial forming units ml-1 in 0.9% saline or 0.9% saline containing 10% v/v plasma to simulate clean and dirty conditions. A syncitial inhibition assay on C8166 lymphoblastoid line was used to determine viral titre. Results indicate that satisfactory disinfection (3-4 log reduction in 2 min) can be achieved using Troclosene and NaOCl at concentrations of 50 ppm and 2500 ppm available chlorine (AvCl2) for clean and soiled conditions respectively. For treatment of blood spillages, the addition of Troclosene and NaOCl solutions (10,000 ppm) to equal volumes of contaminated blood (giving a final AvCl2 concentration of 5000 ppm of blood) was sufficient to produce total kill within 2 min.
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| Classification Tree | Code System | Code | ||
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EPA PESTICIDE CODE |
81404
Created by
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Food Contact Sustance Notif, (FCN No.) |
FCN NO. 495
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admin on Fri Dec 15 19:12:09 UTC 2023 , Edited by admin on Fri Dec 15 19:12:09 UTC 2023
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220-767-7
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100000085611
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4235
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SODIUM DICHLOROISOCYANURATE
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C011765
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07M9U9U0LK
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SUB22094
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07M9U9U0LK
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DTXSID3024994
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1537575
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2893-78-9
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517121
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ACTIVE MOIETY
SUBSTANCE RECORD
