U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C3Cl2N3O3.Na
Molecular Weight 219.946
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TROCLOSENE SODIUM

SMILES

[Na+].ClN1C(=O)[N-]C(=O)N(Cl)C1=O

InChI

InChIKey=MSFGZHUJTJBYFA-UHFFFAOYSA-M
InChI=1S/C3HCl2N3O3.Na/c4-7-1(9)6-2(10)8(5)3(7)11;/h(H,6,9,10);/q;+1/p-1

HIDE SMILES / InChI

Description

Troclosene is chlorinated hydroxytriazine and it is used as a source of free available chlorine, in the form of hypochlorous acid, for the disinfection of water. It kills bacteria, bacterial spores, cysts, algae, fungi, protozoa and virus and are especially lethal to Entamoeba histolytica. Troclosene kills mastitis-causing organisms. It is now widely available for household water treatment. It does not prevent diarrhea but improved water quality.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
PubMed

PubMed

TitleDatePubMed
Virucidal agents in the eve of manorapid synergy.
2007 Sep 13
[Specific antisepsis and environmental disinfection in preventing "Clostridium difficile associated diarrhea"].
2009 Nov-Dec
Collection of indonaphthol blue on a membrane filter for the spectrophotometric determination of ammonia with 1-naphthol and dichloroisocyanurate.
2010
Disinfection efficacy of sodium dichloroisocyanurate (NADCC) against common food-borne intestinal protozoa.
2010 Apr
Improvements to water purification and sanitation infrastructure may reduce the diarrheal burden in a marginalized and flood prone population in remote Nicaragua.
2010 Dec 8
Disinfection by-product formation and mitigation strategies in point-of-use chlorination with sodium dichloroisocyanurate in Tanzania.
2010 Jul
Jasmonic acid and ethylene modulate local responses to wounding and simulated herbivory in Nicotiana attenuata leaves.
2010 Jun
Root canal irrigants.
2010 Oct
Field assessment of a novel household-based water filtration device: a randomised, placebo-controlled trial in the Democratic Republic of Congo.
2010 Sep 10
1,1'-Azobis-1,2,3-triazole: a high-nitrogen compound with stable N8 structure and photochromism.
2010 Sep 8
Patents

Patents

Sample Use Guides

In Vitro Use Guide
Viral suspensions were prepared containing 10(4)-10(5) syncitial forming units ml-1 in 0.9% saline or 0.9% saline containing 10% v/v plasma to simulate clean and dirty conditions. A syncitial inhibition assay on C8166 lymphoblastoid line was used to determine viral titre. Results indicate that satisfactory disinfection (3-4 log reduction in 2 min) can be achieved using Troclosene and NaOCl at concentrations of 50 ppm and 2500 ppm available chlorine (AvCl2) for clean and soiled conditions respectively. For treatment of blood spillages, the addition of Troclosene and NaOCl solutions (10,000 ppm) to equal volumes of contaminated blood (giving a final AvCl2 concentration of 5000 ppm of blood) was sufficient to produce total kill within 2 min.
Name Type Language
TROCLOSENE SODIUM
HSDB   MART.   WHO-DD  
Common Name English
TROCLOSENE SODIUM [WHO-DD]
Common Name English
TROCLOSENE SODIUM [HSDB]
Common Name English
SODIUM TROCLOSENE
Common Name English
SODIUM DICHLORO-S-TRIAZINETRIONE
Systematic Name English
SODIUM DICHLOROCYANURATE
Common Name English
TROCLOSENE SODIUM [MART.]
Common Name English
SODIUM DICHLOROISOCYANURATE
Common Name English
NADCC
Common Name English
DICHLOROSAN
Common Name English
1,3,5-TRIAZINE-2,4,6(1H,3H,5H)-TRIONE, 1,3-DICHLORO-, SODIUM SALT (1:1)
Common Name English
ACTISEPT
Brand Name English
SODIUM DICHLOROISOCYANURATE [JAN]
Common Name English
DICHLOROISOCYANURIC ACID SODIUM SALT
Common Name English
CLEARON
Brand Name English
NEOCHLOR 55
Brand Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 81404
Created by admin on Tue Mar 06 12:08:08 UTC 2018 , Edited by admin on Tue Mar 06 12:08:08 UTC 2018
Food Contact Sustance Notif, (FCN No.) FCN NO. 495
Created by admin on Tue Mar 06 12:08:08 UTC 2018 , Edited by admin on Tue Mar 06 12:08:08 UTC 2018
Code System Code Type Description
ECHA (EC/EINECS)
220-767-7
Created by admin on Tue Mar 06 12:08:08 UTC 2018 , Edited by admin on Tue Mar 06 12:08:08 UTC 2018
PRIMARY
HSDB
2893-78-9
Created by admin on Tue Mar 06 12:08:08 UTC 2018 , Edited by admin on Tue Mar 06 12:08:08 UTC 2018
PRIMARY
WIKIPEDIA
SODIUM DICHLOROISOCYANURATE
Created by admin on Tue Mar 06 12:08:08 UTC 2018 , Edited by admin on Tue Mar 06 12:08:08 UTC 2018
PRIMARY
MESH
C011765
Created by admin on Tue Mar 06 12:08:08 UTC 2018 , Edited by admin on Tue Mar 06 12:08:08 UTC 2018
PRIMARY
EVMPD
SUB22094
Created by admin on Tue Mar 06 12:08:08 UTC 2018 , Edited by admin on Tue Mar 06 12:08:08 UTC 2018
PRIMARY
EPA CompTox
2893-78-9
Created by admin on Tue Mar 06 12:08:08 UTC 2018 , Edited by admin on Tue Mar 06 12:08:08 UTC 2018
PRIMARY
RXCUI
1537575
Created by admin on Tue Mar 06 12:08:08 UTC 2018 , Edited by admin on Tue Mar 06 12:08:08 UTC 2018
PRIMARY RxNorm
CAS
2893-78-9
Created by admin on Tue Mar 06 12:08:08 UTC 2018 , Edited by admin on Tue Mar 06 12:08:08 UTC 2018
PRIMARY