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Details

Stereochemistry ABSOLUTE
Molecular Formula C12H19NO4
Molecular Weight 241.2836
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GPI-1485

SMILES

CCC(C)(C)C(=O)C(=O)N1CCC[C@H]1C(O)=O

InChI

InChIKey=FOPALECPEUVCTL-QMMMGPOBSA-N
InChI=1S/C12H19NO4/c1-4-12(2,3)9(14)10(15)13-7-5-6-8(13)11(16)17/h8H,4-7H2,1-3H3,(H,16,17)/t8-/m0/s1

HIDE SMILES / InChI

Description

GPI-1485 belongs to a class of small molecule compounds called neuroimmunophilin ligands. This class of compounds has been shown to repair and regenerate damaged nerves without affecting normal, healthy nerves. GPI-1485 binds to FK-506-binding proteins. Phase 2 studies have been conducted to assess whether GPI-1485 is able to delay or stop disease progression and improve symptoms in patients with Parkinson's disease (PD), and whether GPI-1485 can help preserve erectile function after prostatectomy.

Originator

Approval Year