Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C15H22N2O18P2 |
Molecular Weight | 580.2853 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 9 / 9 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)O[C@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)O[C@H]([C@@H]1O)N3C=CC(=O)NC3=O
InChI
InChIKey=HDYANYHVCAPMJV-LXQIFKJMSA-N
InChI=1S/C15H22N2O18P2/c18-5-1-2-17(15(26)16-5)12-9(22)6(19)4(32-12)3-31-36(27,28)35-37(29,30)34-14-10(23)7(20)8(21)11(33-14)13(24)25/h1-2,4,6-12,14,19-23H,3H2,(H,24,25)(H,27,28)(H,29,30)(H,16,18,26)/t4-,6-,7+,8+,9-,10-,11+,12-,14-/m1/s1
Approval Year
PubMed
Title | Date | PubMed |
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Distribution of UDP-glucuronosyltransferase and its endogenous substrate uridine 5'-diphosphoglucuronic acid in human tissues. | 1991 |
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N-glucuronidation reactions. II. Relative N-glucuronidation reactivity of methylbiphenyl tetrazole, methylbiphenyl triazole, and methylbiphenyl imidazole in rat, monkey, and human hepatic microsomes. | 1994 Jul-Aug |
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Uridine 5'-diphosphoglucuronic acid (UDPGLcUA) in the human fetal liver, kidney and placenta. | 2000 Jul-Dec |
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In vitro glucuronidation of the cyclin-dependent kinase inhibitor flavopiridol by rat and human liver microsomes: involvement of UDP-glucuronosyltransferases 1A1 and 1A9. | 2001 Apr |
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Molecular characterization of human UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter, a novel nucleotide sugar transporter with dual substrate specificity. | 2001 Apr 20 |
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High-performance liquid chromatographic assay for acetaminophen glucuronide in human liver microsomes. | 2001 Apr 5 |
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Cloning, pharmacology, and tissue distribution of G-protein-coupled receptor GPR105 (KIAA0001) rodent orthologs. | 2001 Dec |
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The donor substrate specificity of the human beta 1,3-glucuronosyltransferase I toward UDP-glucuronic acid is determined by two crucial histidine and arginine residues. | 2002 Jul 12 |
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Structure-activity studies of glucose transfer: determination of the spontaneous rates of hydrolysis of uridine 5'-diphospho-alpha-D-glucose (UDPG) and uridine 5'-diphospho-alpha-D-glucuronic acid (UDPGA). | 2003 May 15 |
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Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia). | 2004 Mar |
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Urinary excretion of arbutin metabolites after oral administration of bearberry leaf extracts. | 2005 Feb |
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Regulation of UDP-glucuronosyltransferase (UGT) 1A1 by progesterone and its impact on labetalol elimination. | 2008 Jan |
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Gi-dependent cell signaling responses of the human P2Y14 receptor in model cell systems. | 2009 Jul |
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A cardiac-specific robotized cellular assay identified families of human ligands as inducers of PGC-1α expression and mitochondrial biogenesis. | 2012 |
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Towards a systematic analysis of human short-chain dehydrogenases/reductases (SDR): Ligand identification and structure-activity relationships. | 2015 Jun 5 |
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Code System | Code | Type | Description | ||
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Uridine diphosphate glucuronic acid
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DTXSID00903961
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04SZC4MEFQ
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17200
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17473
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2616-64-0
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SUBSTANCE RECORD