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Details

Stereochemistry ABSOLUTE
Molecular Formula C15H22N2O18P2
Molecular Weight 580.2853
Optical Activity UNSPECIFIED
Defined Stereocenters 9 / 9
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of URIDINE DIPHOSPHATE GLUCURONIC ACID

SMILES

O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)O[C@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)O[C@H]([C@@H]1O)N3C=CC(=O)NC3=O

InChI

InChIKey=HDYANYHVCAPMJV-LXQIFKJMSA-N
InChI=1S/C15H22N2O18P2/c18-5-1-2-17(15(26)16-5)12-9(22)6(19)4(32-12)3-31-36(27,28)35-37(29,30)34-14-10(23)7(20)8(21)11(33-14)13(24)25/h1-2,4,6-12,14,19-23H,3H2,(H,24,25)(H,27,28)(H,29,30)(H,16,18,26)/t4-,6-,7+,8+,9-,10-,11+,12-,14-/m1/s1

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Distribution of UDP-glucuronosyltransferase and its endogenous substrate uridine 5'-diphosphoglucuronic acid in human tissues.
1991
N-glucuronidation reactions. II. Relative N-glucuronidation reactivity of methylbiphenyl tetrazole, methylbiphenyl triazole, and methylbiphenyl imidazole in rat, monkey, and human hepatic microsomes.
1994 Jul-Aug
Uridine 5'-diphosphoglucuronic acid (UDPGLcUA) in the human fetal liver, kidney and placenta.
2000 Jul-Dec
In vitro glucuronidation of the cyclin-dependent kinase inhibitor flavopiridol by rat and human liver microsomes: involvement of UDP-glucuronosyltransferases 1A1 and 1A9.
2001 Apr
Molecular characterization of human UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter, a novel nucleotide sugar transporter with dual substrate specificity.
2001 Apr 20
High-performance liquid chromatographic assay for acetaminophen glucuronide in human liver microsomes.
2001 Apr 5
Cloning, pharmacology, and tissue distribution of G-protein-coupled receptor GPR105 (KIAA0001) rodent orthologs.
2001 Dec
The donor substrate specificity of the human beta 1,3-glucuronosyltransferase I toward UDP-glucuronic acid is determined by two crucial histidine and arginine residues.
2002 Jul 12
Structure-activity studies of glucose transfer: determination of the spontaneous rates of hydrolysis of uridine 5'-diphospho-alpha-D-glucose (UDPG) and uridine 5'-diphospho-alpha-D-glucuronic acid (UDPGA).
2003 May 15
Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia).
2004 Mar
Urinary excretion of arbutin metabolites after oral administration of bearberry leaf extracts.
2005 Feb
Regulation of UDP-glucuronosyltransferase (UGT) 1A1 by progesterone and its impact on labetalol elimination.
2008 Jan
Gi-dependent cell signaling responses of the human P2Y14 receptor in model cell systems.
2009 Jul
A cardiac-specific robotized cellular assay identified families of human ligands as inducers of PGC-1α expression and mitochondrial biogenesis.
2012
Towards a systematic analysis of human short-chain dehydrogenases/reductases (SDR): Ligand identification and structure-activity relationships.
2015 Jun 5
Name Type Language
URIDINE DIPHOSPHATE GLUCURONIC ACID
Common Name English
URIDINE 5'-DIPHOSPHO-.ALPHA.-D-GLUCURONIC ACID
Common Name English
UDP-GLCUA
Common Name English
UDP-D-GLUCURONIC ACID
Common Name English
.ALPHA.-D-GLUCOPYRANURONIC ACID, 1->P'-ESTER WITH URIDINE 5'-(TRIHYDROGEN DIPHOSPHATE)
Common Name English
UDP-.ALPHA.-D-GLUCURONIC ACID
Common Name English
UDP-GLUCURONIC ACID
Common Name English
Code System Code Type Description
WIKIPEDIA
Uridine diphosphate glucuronic acid
Created by admin on Sat Dec 16 08:05:34 GMT 2023 , Edited by admin on Sat Dec 16 08:05:34 GMT 2023
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EPA CompTox
DTXSID00903961
Created by admin on Sat Dec 16 08:05:34 GMT 2023 , Edited by admin on Sat Dec 16 08:05:34 GMT 2023
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FDA UNII
04SZC4MEFQ
Created by admin on Sat Dec 16 08:05:34 GMT 2023 , Edited by admin on Sat Dec 16 08:05:34 GMT 2023
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CHEBI
17200
Created by admin on Sat Dec 16 08:05:34 GMT 2023 , Edited by admin on Sat Dec 16 08:05:34 GMT 2023
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PUBCHEM
17473
Created by admin on Sat Dec 16 08:05:34 GMT 2023 , Edited by admin on Sat Dec 16 08:05:34 GMT 2023
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CAS
2616-64-0
Created by admin on Sat Dec 16 08:05:34 GMT 2023 , Edited by admin on Sat Dec 16 08:05:34 GMT 2023
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