Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C24H26N2O4 |
| Molecular Weight | 406.4742 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 5 / 5 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=C2O[C@H]3[C@H](CC[C@H]4[C@H]5CC(C=C1)=C2[C@@]34CCN5C)OC(=O)C6=CC=CN=C6
InChI
InChIKey=GTGRMWCOZHEYRL-MJFIPZRTSA-N
InChI=1S/C24H26N2O4/c1-26-11-9-24-16-6-8-19(29-23(27)15-4-3-10-25-13-15)22(24)30-21-18(28-2)7-5-14(20(21)24)12-17(16)26/h3-5,7,10,13,16-17,19,22H,6,8-9,11-12H2,1-2H3/t16-,17+,19-,22-,24-/m0/s1
Nicodicodine is a cough suppressant and analgesic. It was first synthesized in 1904. It is a Schedule III drug. Nicodicodine is metabolised in the liver to dihydromorphine. Since the final active metabolite is the slightly stronger opiate than morphine, nicodicodine can be expected to be more potent and longer acting than nicocodeine.
Approval Year
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| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C66917
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DTXSID40230642
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CHEMBL2104623
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212-365-5
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5464304
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1963
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SUB09235MIG
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100000084190
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C84010
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Nicodicodine
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808-24-2
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ACTIVE MOIETY
