U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C44H88NO8P
Molecular Weight 790.1452
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE

SMILES

CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCCCC

InChI

InChIKey=NRJAVPSFFCBXDT-HUESYALOSA-N
InChI=1S/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1

HIDE SMILES / InChI
1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) a non-pyrogenic phospholipid, is used to produce liposomes that are capable of being loaded with a molecule of choice. This compound is also used as an inactive ingredient of drugs, e.g., for TOBI PODHALER which is indicated for the management of cystic fibrosis patients with Pseudomonas aeruginosa.

Approval Year

PubMed

PubMed

TitleDatePubMed
Interfacial molecular interactions based on the conformation recognition between the insoluble antitumor drug AD-1 and DSPC.
2016 Oct 1
Uptake of New Lipid-coated Nanoparticles Containing Falcarindiol by Human Mesenchymal Stem Cells.
2019 Feb 9
Patents
Name Type Language
1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE
II  
Common Name English
DISTEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Common Name English
1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE (DSPC)
Common Name English
DISTEAROYL GLYCEROPHOSPHOCHOLINE [INCI]
Common Name English
L-DISTEAROYLLECITHIN
Common Name English
DISTEAROYL-L-.ALPHA.-LECITHIN
Common Name English
DISTEAROYL GLYCEROPHOSPHOCHOLINE
INCI  
INCI  
Official Name English
DSPC R-ISOMER
Common Name English
NSC-725285
Code English
DSPC
Common Name English
1,2-DISTEARIN SN-3-PHOSPHORYLCHOLINE
Common Name English
1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE [II]
Common Name English
1,2-DIASTEAROYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Common Name English
3,5,9-TRIOXA-4-PHOSPHAHEPTACOSAN-1-AMINIUM, 4-HYDROXY-N,N,N-TRIMETHYL-10-OXO-7-((1-OXOOCTADECYL)OXY)-, INNER SALT, 4-OXIDE, (7R)-
Common Name English
Code System Code Type Description
NSC
725285
Created by admin on Fri Dec 16 16:40:43 UTC 2022 , Edited by admin on Fri Dec 16 16:40:43 UTC 2022
PRIMARY
ECHA (EC/EINECS)
212-440-2
Created by admin on Fri Dec 16 16:40:43 UTC 2022 , Edited by admin on Fri Dec 16 16:40:43 UTC 2022
PRIMARY
PUBCHEM
94190
Created by admin on Fri Dec 16 16:40:43 UTC 2022 , Edited by admin on Fri Dec 16 16:40:43 UTC 2022
PRIMARY
WIKIPEDIA
Distearoylphosphatidylcholine
Created by admin on Fri Dec 16 16:40:43 UTC 2022 , Edited by admin on Fri Dec 16 16:40:43 UTC 2022
PRIMARY
CAS
816-94-4
Created by admin on Fri Dec 16 16:40:43 UTC 2022 , Edited by admin on Fri Dec 16 16:40:43 UTC 2022
PRIMARY
MESH
C010942
Created by admin on Fri Dec 16 16:40:43 UTC 2022 , Edited by admin on Fri Dec 16 16:40:43 UTC 2022
PRIMARY
DAILYMED
043IPI2M0K
Created by admin on Fri Dec 16 16:40:43 UTC 2022 , Edited by admin on Fri Dec 16 16:40:43 UTC 2022
PRIMARY
EVMPD
SUB32413
Created by admin on Fri Dec 16 16:40:43 UTC 2022 , Edited by admin on Fri Dec 16 16:40:43 UTC 2022
PRIMARY
EPA CompTox
DTXSID20231218
Created by admin on Fri Dec 16 16:40:43 UTC 2022 , Edited by admin on Fri Dec 16 16:40:43 UTC 2022
PRIMARY
FDA UNII
043IPI2M0K
Created by admin on Fri Dec 16 16:40:43 UTC 2022 , Edited by admin on Fri Dec 16 16:40:43 UTC 2022
PRIMARY