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Details

Stereochemistry ACHIRAL
Molecular Formula C19H24O2S
Molecular Weight 316.458
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PRIFELONE

SMILES

CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C(=O)C2=CC=CS2

InChI

InChIKey=WAAVMZLJRXYRMA-UHFFFAOYSA-N
InChI=1S/C19H24O2S/c1-18(2,3)13-10-12(16(20)15-8-7-9-22-15)11-14(17(13)21)19(4,5)6/h7-11,21H,1-6H3

HIDE SMILES / InChI
Prifelone (also known as R-830) is a thiophene derivative patented by American pharmaceutical company Riker Laboratories, Inc. As an antiinflammatory, analgesic, and antipyretic compound. In vitro, Prifelone acts as a nonsteroidal anti-inflammatory drug and inhibits guinea pig lung lipoxygenase and bovine seminal vesicle cyclooxygenase. In preclinical studies, Prifelone shows potent anti-inflammatory activity in carrageenan-induced edema and adjuvant arthritis of the rat and ultraviolet-induced erythema in the guinea pig

Approval Year

PubMed

PubMed

TitleDatePubMed
Patents

Patents

Name Type Language
PRIFELONE
INN   USAN  
USAN   INN  
Official Name English
PRIFELONE [USAN]
Common Name English
R-830
Code English
3,5-Di-tert-butyl-4-hydroxyphenyl 2-thienyl ketone
Systematic Name English
R-830T
Code English
prifelone [INN]
Common Name English
METHANONE, (3,5-BIS(1,1-DIMETHYLETHYL)-4-HYDROXYPHENYL)-2-THIENYL-
Systematic Name English
S-16820
Code English
Classification Tree Code System Code
NCI_THESAURUS C257
Created by admin on Sat Dec 16 15:56:19 GMT 2023 , Edited by admin on Sat Dec 16 15:56:19 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C80567
Created by admin on Sat Dec 16 15:56:19 GMT 2023 , Edited by admin on Sat Dec 16 15:56:19 GMT 2023
PRIMARY
PUBCHEM
71751
Created by admin on Sat Dec 16 15:56:19 GMT 2023 , Edited by admin on Sat Dec 16 15:56:19 GMT 2023
PRIMARY
MESH
C037195
Created by admin on Sat Dec 16 15:56:19 GMT 2023 , Edited by admin on Sat Dec 16 15:56:19 GMT 2023
PRIMARY
EPA CompTox
DTXSID90219583
Created by admin on Sat Dec 16 15:56:19 GMT 2023 , Edited by admin on Sat Dec 16 15:56:19 GMT 2023
PRIMARY
SMS_ID
100000081653
Created by admin on Sat Dec 16 15:56:19 GMT 2023 , Edited by admin on Sat Dec 16 15:56:19 GMT 2023
PRIMARY
INN
6158
Created by admin on Sat Dec 16 15:56:19 GMT 2023 , Edited by admin on Sat Dec 16 15:56:19 GMT 2023
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FDA UNII
0414BW860U
Created by admin on Sat Dec 16 15:56:19 GMT 2023 , Edited by admin on Sat Dec 16 15:56:19 GMT 2023
PRIMARY
USAN
X-30
Created by admin on Sat Dec 16 15:56:19 GMT 2023 , Edited by admin on Sat Dec 16 15:56:19 GMT 2023
PRIMARY
ChEMBL
CHEMBL8846
Created by admin on Sat Dec 16 15:56:19 GMT 2023 , Edited by admin on Sat Dec 16 15:56:19 GMT 2023
PRIMARY
CAS
69425-13-4
Created by admin on Sat Dec 16 15:56:19 GMT 2023 , Edited by admin on Sat Dec 16 15:56:19 GMT 2023
PRIMARY
EVMPD
SUB10038MIG
Created by admin on Sat Dec 16 15:56:19 GMT 2023 , Edited by admin on Sat Dec 16 15:56:19 GMT 2023
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