Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C30H30ClFN2O3 |
| Molecular Weight | 521.022 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCC[C@@H]([C@@H](C1=CNC2=C(F)C=C(C)C=C12)C3=CC=C(Cl)C=C3)C4=CC=C(C=C4)C(=O)NCCC(O)=O
InChI
InChIKey=FYRJJCYFYLLOSC-LXFBAYGMSA-N
InChI=1S/C30H30ClFN2O3/c1-3-4-23(19-5-7-21(8-6-19)30(37)33-14-13-27(35)36)28(20-9-11-22(31)12-10-20)25-17-34-29-24(25)15-18(2)16-26(29)32/h5-12,15-17,23,28,34H,3-4,13-14H2,1-2H3,(H,33,37)(H,35,36)/t23-,28+/m1/s1
MK 3577 is an orally active glucagon receptor antagonist which was under development by Merck & Co for the treatment of type 2 diabetes mellitus. MK 3577 demonstrate activity in cellular models and preclinical trials. In phase II clinical trials MK 3577 shows good efficacy and acceptable level of adverse events, but no further development reports were published.
Approval Year
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| Code System | Code | Type | Description | ||
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46240797
Created by
admin on Sat Dec 16 11:42:29 GMT 2023 , Edited by admin on Sat Dec 16 11:42:29 GMT 2023
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DB14957
Created by
admin on Sat Dec 16 11:42:29 GMT 2023 , Edited by admin on Sat Dec 16 11:42:29 GMT 2023
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03TW1410NL
Created by
admin on Sat Dec 16 11:42:29 GMT 2023 , Edited by admin on Sat Dec 16 11:42:29 GMT 2023
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PRIMARY | |||
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1019112-29-8
Created by
admin on Sat Dec 16 11:42:29 GMT 2023 , Edited by admin on Sat Dec 16 11:42:29 GMT 2023
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PRIMARY |
ACTIVE MOIETY
