4-Aminopyrazolo[3,4-d]pyrimidine

NC1=C2C=NNC2=NC=N1

InChIKey=LHCPRYRLDOSKHK-UHFFFAOYSA-N

InChI=1S/C5H5N5/c6-4-3-1-9-10-5(3)8-2-7-4/h1-2H,(H3,6,7,8,9,10)

Targets

Primary Target	Pharmacology	Condition	Potency
Xanthine dehydrogenase 33 Target ID: CHEMBL3649 Sources: https://www.ncbi.nlm.nih.gov/pubmed/13438887	Inhibitor 8504
lipid metabolic process 22 Target ID: GO:0006629 Sources: https://www.ncbi.nlm.nih.gov/pubmed/5098395 \| https://www.ncbi.nlm.nih.gov/pubmed/14167668 \| https://www.ncbi.nlm.nih.gov/pubmed/217622	Modulator 846

PubMed

Title	Date	PubMed
Trypanosoma brucei adenine-phosphoribosyltransferases mediate adenine salvage and aminopurinol susceptibility but not adenine toxicity.	2014-04	24596669
Mechanisms of action of pyrazolopyrimidines in Leishmania donovani.	1986-07-15	2424909
Antitrypanosomal effect of allopurinol: conversion in vivo to aminopyrazolopyrimidine nucleotides by Trypanosoma curzi.	1978-09-15	356267

Name

Type

Language

NSC-1393

Preferred Name

English

4-Aminopyrazolo[3,4-d]pyrimidine

Systematic Name

English

1H-PYRAZOLO(3,4-D)PYRIMIDIN-4-AMINE

Systematic Name

English

8-AZA-7-DEAZAADENINE

Common Name

English

1H-PYRAZOLO(3,4-D)PYRIMIDINE, 4-AMINO-

Systematic Name

English

4-AMINO-1H-PYRAZOLO(3,4-D)PYRIMIDINE

Systematic Name

English

Pyrazoloadenine

Common Name

English

7-DEAZA-8-AZAADENINE

Common Name

English

1H-PYRAZOLO(3,4-D)PYRIMIDIN-4-YLAMINE

Systematic Name

English

Code System Code Type Description

FDA UNII

0356MAT9LX