Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H6O3 |
| Molecular Weight | 126.11 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC1=CC=CC(O)=C1O
InChI
InChIKey=WQGWDDDVZFFDIG-UHFFFAOYSA-N
InChI=1S/C6H6O3/c7-4-2-1-3-5(8)6(4)9/h1-3,7-9H
Approval Year
Doses
| Dose | Population | Adverse events |
|---|---|---|
10 % 1 times / day multiple, topical Dose: 10 %, 1 times / day Route: topical Route: multiple Dose: 10 %, 1 times / day Sources: |
unhealthy, 77 years n = 1 Health Status: unhealthy Condition: Psoriasis Age Group: 77 years Sex: M Population Size: 1 Sources: |
Disc. AE: Squamous cell carcinoma... AEs leading to discontinuation/dose reduction: Squamous cell carcinoma Sources: |
10 g single, topical Dose: 10 g Route: topical Route: single Dose: 10 g Sources: |
unknown n = 1 Health Status: unknown Population Size: 1 Sources: |
Other AEs: Adverse event... Other AEs: Adverse event (grade 5) Sources: |
AEs
| AE | Significance | Dose | Population |
|---|---|---|---|
| Squamous cell carcinoma | Disc. AE | 10 % 1 times / day multiple, topical Dose: 10 %, 1 times / day Route: topical Route: multiple Dose: 10 %, 1 times / day Sources: |
unhealthy, 77 years n = 1 Health Status: unhealthy Condition: Psoriasis Age Group: 77 years Sex: M Population Size: 1 Sources: |
| Adverse event | grade 5 | 10 g single, topical Dose: 10 g Route: topical Route: single Dose: 10 g Sources: |
unknown n = 1 Health Status: unknown Population Size: 1 Sources: |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Asaricin, the main component of Ocotea opifera Mart. essential oil. | 2001 |
|
| Measurement of dissolved oxygen based on enhanced cerium(IV) chemiluminescence. | 2001 Jan |
|
| Reversal of pyrogallol-induced delay in gastric emptying in rats by ginger (Zingiber officinale). | 2001 Nov |
|
| Hydrogen-bonded molecular capsules are stable in polar media. | 2001 Nov 21 |
|
| Physiological activity of some aminophosphonates. | 2001 Nov-Dec |
|
| Blood copper concentrations and cuproenzyme activities in a colony of cats. | 2002 |
|
| Catechol- and pyrogallol-type flavonoids. Analysis of tea catechins in plasma. | 2002 |
|
| Superoxide dismutase activities of spermatozoa and seminal plasma are not correlated with male infertility. | 2002 |
|
| Superoxide dismutase kinetics. | 2002 |
|
| Ab initio study of the mechanism of singlet-dioxygen addition to hydroxyaromatic compounds: negative evidence for the involvement of peroxa and endoperoxide intermediates. | 2002 Aug |
|
| Adsorption and detection of some phenolic compounds by rice husk ash of Kenyan origin. | 2002 Dec |
|
| Contractile responses to reactive oxygen species in the canine basilar artery in vitro: selective inhibitory effect of MCI-186, a new hydroxyl radical scavenger. | 2002 Dec |
|
| Detection of low-molecular-weight proteins in urine by dipsticks. | 2002 Dec |
|
| O2(-)-mediated impairment of coronary arterial relaxation is prevented by overnight treatment with 1 nM beta-estradiol. | 2002 Dec |
|
| The contribution of the pyrogallol moiety to the superoxide radical scavenging activity of flavonoids. | 2002 Jan |
|
| Degradation of water-insoluble dyes by microperoxidase-11, an effective and stable peroxidative catalyst in hydrophilic organic media. | 2002 Jan-Feb |
|
| Identification of pyrogallol as an antiproliferative compound present in extracts from the medicinal plant Emblica officinalis: effects on in vitro cell growth of human tumor cell lines. | 2002 Jul |
|
| Chemical stress-responsive genes from the lignin-degrading fungus Phanerochaete chrysosporium exposed to dibenzo-p-dioxin. | 2002 Jul 2 |
|
| Engineering the proximal heme cavity of catalase-peroxidase. | 2002 Jul 25 |
|
| Aroma biosynthesis in strawberry: s-adenosylmethionine:furaneol o-methyltransferase activity in ripening fruits. | 2002 Jul 3 |
|
| Effect of drying method on the volatiles in bay leaf (Laurus nobilis L.). | 2002 Jul 31 |
|
| Kinetic-spectrophotometric determination of palladium in hydrogenation catalyst by its catalytic effect on the oxidation of pyrogallol red by hydrogen peroxide. | 2002 Jun |
|
| Structural requirements of flavonoids and related compounds for aldose reductase inhibitory activity. | 2002 Jun |
|
| Antioxidant activity of dodecyl gallate. | 2002 Jun 5 |
|
| Evaluation of antioxidant properties of root bark of Hemidesmus indicus R. Br. (Anantmul). | 2002 Mar |
|
| Hyperglycemia increases endothelial superoxide that impairs smooth muscle cell Na+-K+-ATPase activity. | 2002 Mar |
|
| Selective detection of o-diphenols on copper-plated screen-printed electrodes. | 2002 Mar 1 |
|
| Diphenol activation of the monophenolase and diphenolase activities of field bean (Dolichos lablab) polyphenol oxidase. | 2002 Mar 13 |
|
| A reassessment of the peroxynitrite scavenging activity of uric acid. | 2002 May |
|
| Isolation from a shea cake digester of a tannin-degrading Streptococcus gallolyticus strain that decarboxylates protocatechuic and hydroxycinnamic acids, and emendation of the species. | 2002 May |
|
| The effect of oxidative stress on endothelium-dependent and nitric oxide donor-induced relaxation: implications for nitrate tolerance. | 2002 May |
|
| Production of interleukin-6 by skeletal myotubes: role of reactive oxygen species. | 2002 May |
|
| Deoxygenation of polyhydroxybenzenes: an alternative strategy for the benzene-free synthesis of aromatic chemicals. | 2002 May 29 |
|
| Flow-injection spectrophotometric determination of periodate and iodate by their reaction with pyrogallol red in acidic media. | 2002 Nov |
|
| Screening of ubiquitous plant constituents for COX-2 inhibition with a scintillation proximity based assay. | 2002 Nov |
|
| Purification and characterization of an extracellular laccase from the edible mushroom Lentinula edodes, and decolorization of chemically different dyes. | 2002 Nov |
|
| Purification and characterization of soluble peroxidase from oil palm (Elaeis guineensis Jacq) leaf. | 2002 Nov |
|
| The preparation and characterization of an antimicrobial polypeptide from the loach, Misgurnus anguillicaudatus. | 2002 Nov |
|
| [The determination of total concentration and activity of antioxidants in foodstuffs]. | 2002 Nov-Dec |
|
| Pyrogallol-induced hepatotoxicity in rats: a model to evaluate antioxidant hepatoprotective agents. | 2002 Oct |
|
| Structural requirements of flavonoids for inhibition of antigen-Induced degranulation, TNF-alpha and IL-4 production from RBL-2H3 cells. | 2002 Oct |
|
| Activity-guided fractionation of green tea extract with antiproliferative activity against human stomach cancer cells. | 2002 Sep |
|
| Replacement of active-site cysteine-436 by serine converts cytochrome P450 2B4 into an NADPH oxidase with negligible monooxygenase activity. | 2002 Sep 20 |
|
| High glucose impairs superoxide production from isolated blood neutrophils. | 2003 Apr |
|
| Ketamine and midazolam differentially inhibit nonadrenergic noncholinergic lower esophageal sphincter relaxation in rabbits: role of superoxide anion and nitric oxide synthase. | 2003 Feb |
|
| Roles of human liver cytochrome P450 3A4 and 1A2 enzymes in the oxidation of myristicin. | 2003 Feb 3 |
|
| Method for analysis of tannic acid and its metabolites in biological samples: application to tannic acid metabolism in the rat. | 2003 Jan 1 |
|
| Antioxidant activity and characterization of volatile constituents of Taheebo (Tabebuia impetiginosa Martius ex DC). | 2003 Jan 1 |
|
| Oxidative stress, NO* and smooth muscle cell extracellular superoxide dismutase expression. | 2003 Jan 2 |
|
| Metabolic activation of 3-hydroxyanisole by isolated rat hepatocytes. | 2003 Jan 6 |
Patents
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Code | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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C80909
Created by
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87-66-1
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100000078934
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D011748
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201-762-9
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01Y4A2QXY0
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16164
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m9382
Created by
admin on Fri Dec 15 15:18:45 GMT 2023 , Edited by admin on Fri Dec 15 15:18:45 GMT 2023
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PRIMARY | Merck Index | ||
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Pyrogallol
Created by
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DTXSID6025983
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C45678
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CONCEPT | Industrial Aid | ||
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1057
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CHEMBL307145
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9022
Created by
admin on Fri Dec 15 15:18:45 GMT 2023 , Edited by admin on Fri Dec 15 15:18:45 GMT 2023
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PRIMARY | RxNorm | ||
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SUB15064MIG
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5035
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794
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SUBSTANCE RECORD
