TETRAMETHYLTHIURAM MONOSULFIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

US Approved Allergenic Extract (1994)

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H12N2S3
Molecular Weight	208.368
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TETRAMETHYLTHIURAM MONOSULFIDE

Structure Search

SMILES

CN(C)C(=S)SC(=S)N(C)C

InChI

InChIKey=REQPQFUJGGOFQL-UHFFFAOYSA-N

InChI=1S/C6H12N2S3/c1-7(2)5(9)11-6(10)8(3)4/h1-4H3

HIDE SMILES / InChI

Description
Sources: http://www.chemotechnique.se/get_pdf.php?l=en&p=263

Tetramethylthiuram monosulfide (TMTM) is used as a secondary accelerator and activator in the processing of natural and butyl rubbers. It is used as a fungicide, and insecticide.

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2596

PubMed

PubMed

Title	Date	PubMed
Dithiocarbamates induce craniofacial abnormalities and downregulate sox9a during zebrafish development.	2010-09	20530235
Contact allergy to thiurams: multifactorial analysis of clinical surveillance data collected by the IVDK network.	2010-08	20041260
[Preparation and catalysis capability of single crystal Co(C3H6NS2)3 x C6H12N2S3].	2008-12	19256384
Prevalence of type I allergy to natural rubber latex and type IV allergy to latex and rubber additives in operating room staff with glove-related symptoms.	2007-11-24	18034975
Indian aerosols: present status.	2002-12	12492171
Occupational irritant and allergic contact dermatitis among healthcare workers.	2002-02	11918604
Allergic contact dermatitis from natural latex.	2001-09	11526517

Patents

Patents

Sample Use Guides

In Vivo Use Guide

adult female Wistar rats were administrated by gavage of tetramethyl thiurammonosulfide (TMTM, 2 mmol/kg)

Route of Administration: Intragastric

In Vitro Use Guide

Unknown

Name

Type

Language

TETRAMETHYLTHIURAM MONOSULFIDE

Systematic Name

English

NSC-3400

Preferred Name

English

BISDIMETHYLTHIOCARBAMYL SULFIDE

Common Name

English

NSC-4767

Code

English

N,N,N',N'-TETRAMETHYLTHIURAM MONOSULFIDE

Systematic Name

English

BISDIMETHYLTHIOCARBAMYL SULPHIDE

Common Name

English

BIS(DIMETHYLTHIOCARBAMOYL) SULFIDE [HSDB]

Common Name

English

TETRAMETHYLTHIURAM MONOSULPHIDE

Systematic Name

English

Classification Tree Code System Code

NDF-RT

N0000185508

Created by admin on Mon Mar 31 17:59:52 GMT 2025 , Edited by admin on Mon Mar 31 17:59:52 GMT 2025

Code System Code Type Description

NDF-RT

N0000171131

Created by admin on Mon Mar 31 17:59:52 GMT 2025 , Edited by admin on Mon Mar 31 17:59:52 GMT 2025

PRIMARY

Allergens [Chemical/Ingredient]

DAILYMED

01W430XXSQ

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NDF-RT

N0000184306

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Cell-mediated Immunity [PE]

NSC

4767

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HSDB

2902

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CAS

97-74-5

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NSC

3400

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FDA UNII

01W430XXSQ

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EVMPD

SUB61038

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MESH

C034033

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NDF-RT

N0000175629

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Increased Histamine Release [PE]

RXCUI

1363713

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RxNorm

SMS_ID

100000134279

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DRUG BANK

DB14178

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ECHA (EC/EINECS)

202-605-7

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EPA CompTox

DTXSID0021333

Created by admin on Mon Mar 31 17:59:52 GMT 2025 , Edited by admin on Mon Mar 31 17:59:52 GMT 2025

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PUBCHEM

7347

Created by admin on Mon Mar 31 17:59:52 GMT 2025 , Edited by admin on Mon Mar 31 17:59:52 GMT 2025

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WIKIPEDIA

Tetramethylthiuram sulfide

Created by admin on Mon Mar 31 17:59:52 GMT 2025 , Edited by admin on Mon Mar 31 17:59:52 GMT 2025

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ACTIVE MOIETY


					01W430XXSQ

TETRAMETHYLTHIURAM MONOSULFIDE