.ALPHA.-PYRROLIDINOPROPIOPHENONE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C13H17NO
Molecular Weight	203.2802
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of .ALPHA.-PYRROLIDINOPROPIOPHENONE

Structure Search

SMILES

CC(N1CCCC1)C(=O)C2=CC=CC=C2

InChI

InChIKey=KPUJAQRFIJAORQ-UHFFFAOYSA-N

InChI=1S/C13H17NO/c1-11(14-9-5-6-10-14)13(15)12-7-3-2-4-8-12/h2-4,7-8,11H,5-6,9-10H2,1H3

HIDE SMILES / InChI

Originator

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Serotonin 2a (5-HT2a) receptor 237 Target ID: CHEMBL224 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30845376	Antagonist 2849		5.6 null [pKi]
Serotonin transporter 183 Target ID: CHEMBL228 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27799294	Inhibitor 8504		188.0 µM [IC50]
Norepinephrine transporter 197 Target ID: CHEMBL222 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27799294	Inhibitor 8504		0.305 µM [IC50]
Dopamine transporter 183 Target ID: CHEMBL238 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27799294	Inhibitor 8504		0.54 µM [IC50]

PubMed

PubMed

Title	Date	PubMed
Metabolism of the new designer drug alpha-pyrrolidinopropiophenone (PPP) and the toxicological detection of PPP and 4'-methyl-alpha-pyrrolidinopropiophenone (MPPP) studied in rat urine using gas chromatography-mass spectrometry.	2003-11-05	14581066

Patents

Patents

Name

Type

Language

J1.970.279K

Preferred Name

English

.ALPHA.-PYRROLIDINOPROPIOPHENONE

Systematic Name

English

1-PHENYL-2-(1-PYRROLIDINYL)-1-PROPANONE

Systematic Name

English

.ALPHA.-PYRROLIDINO-PROPIOPHENONE

Systematic Name

English

ALPHA-PYRROLIDINOPROPIOPHENONE

Systematic Name

English

.ALPHA.-PPP

Common Name

English

1-PROPANONE, 1-PHENYL-2-(1-PYRROLIDINYL)-

Systematic Name

English

PROPIOPHENONE, 2-(1-PYRROLIDINYL)-

Systematic Name

English

Classification Tree Code System Code

WIKIPEDIA

Designer-drugs-alpha-Pyrrolidinopropiophenone

Created by admin on Mon Mar 31 21:56:54 GMT 2025 , Edited by admin on Mon Mar 31 21:56:54 GMT 2025

Code System Code Type Description

EPA CompTox

DTXSID50897462

Created by admin on Mon Mar 31 21:56:54 GMT 2025 , Edited by admin on Mon Mar 31 21:56:54 GMT 2025

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FDA UNII

01DP8CH58H

Created by admin on Mon Mar 31 21:56:54 GMT 2025 , Edited by admin on Mon Mar 31 21:56:54 GMT 2025

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PUBCHEM

209045

Created by admin on Mon Mar 31 21:56:54 GMT 2025 , Edited by admin on Mon Mar 31 21:56:54 GMT 2025

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WEB RESOURCE

.ALPHA.-PYRROLIDINOPROPIOPHENONE

Created by admin on Mon Mar 31 21:56:54 GMT 2025 , Edited by admin on Mon Mar 31 21:56:54 GMT 2025

PRIMARY

I tried it many times and i can say, that only IV method of using is good to understand the effects. Really. When you eat it or snort it, a-PPP is about nothing special. But 100-150 mg IV it's a proper way. Strong rush, stronger than meth or coke IV

CAS

19134-50-0

Created by admin on Mon Mar 31 21:56:54 GMT 2025 , Edited by admin on Mon Mar 31 21:56:54 GMT 2025

PRIMARY

WIKIPEDIA

ALPHA-PYRROLIDINOPROPIOPHENONE

Created by admin on Mon Mar 31 21:56:54 GMT 2025 , Edited by admin on Mon Mar 31 21:56:54 GMT 2025

PRIMARY

α-Pyrrolidinopropiophenone (α-PPP),[1] is a stimulant drug. It is similar in structure to the appetite suppressant diethylpropion and has analogous effects in animals. Little is known about this compound, but it has been detected by laboratories in Germany as an ingredient in "ecstasy" tablets seized by law enforcement authorities. This drug has been found to produce stimulant effects in animals and presumably also produces these effects in humans, based on the context in which it has been found.

SUBSTANCE RECORD


					01DP8CH58H

.ALPHA.-PYRROLIDINOPROPIOPHENONE