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Details

Stereochemistry RACEMIC
Molecular Formula C13H17NO
Molecular Weight 203.2802
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of .ALPHA.-PYRROLIDINOPROPIOPHENONE

SMILES

CC(N1CCCC1)C(=O)C2=CC=CC=C2

InChI

InChIKey=KPUJAQRFIJAORQ-UHFFFAOYSA-N
InChI=1S/C13H17NO/c1-11(14-9-5-6-10-14)13(15)12-7-3-2-4-8-12/h2-4,7-8,11H,5-6,9-10H2,1H3

HIDE SMILES / InChI

Originator

Farberke Hoechst AG vorm. Meister Lucius & Bruning
2

Approval Year

Unknown
149,124

Targets

Primary TargetPharmacologyConditionPotency
Serotonin 2a (5-HT2a) receptor
237
Antagonist
2,849
 5.6 null [pKi]
Serotonin transporter
183
Inhibitor
8,504
 188.0 µM [IC50]
Norepinephrine transporter
197
Inhibitor
8,504
 0.305 µM [IC50]
Dopamine transporter
183
Inhibitor
8,504
 0.54 µM [IC50]

PubMed

Patents

WO2015063795A2
2
NIH
NCATS
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