U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
Sermorelin, a 29 amino acid analog of human growth hormone-releasing hormone (GHRH), is the shortest synthetic peptide with a full biological activity of GHRH which is used as a diagnostic agent to assess growth hormone (GH) secretion for the purpose of diagnosing growth hormone deficiency. Intravenous and subcutaneous sermorelin specifically stimulate growth hormone secretion from the anterior pituitary. Sermorelin binds to the growth hormone releasing hormone receptor and mimics native GRF in its ability to stimulate growth hormone secretion. Hormone responses to intravenous sermorelin appear to be a rapid and relatively specific test for the diagnosis of growth hormone deficiency.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
GEREF

Approved Use

Diagnosing and treating growth hormone deficiency in children

Launch Date

1990

Sample Use Guides

1 mcg/kg bodyweight
Route of Administration: Intravenous
Name Type Language
SERMORELIN ACETATE
MART.   ORANGE BOOK   USAN   VANDF   WHO-DD  
USAN  
Official Name English
SERMORELIN ACETATE [USAN]
Common Name English
GEREF
Brand Name English
SERMORELIN ACETATE [ORANGE BOOK]
Common Name English
SERMORELIN ACETATE [VANDF]
Common Name English
Sermorelin acetate [WHO-DD]
Common Name English
Growth hormone-releasing factor (human)-(1-29)-peptide amide, acetate (salt), hydrate
Common Name English
SERMORELIN ACETATE [MART.]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 24687
Created by admin on Sat Dec 16 00:25:58 GMT 2023 , Edited by admin on Sat Dec 16 00:25:58 GMT 2023
FDA ORPHAN DRUG 61491
Created by admin on Sat Dec 16 00:25:58 GMT 2023 , Edited by admin on Sat Dec 16 00:25:58 GMT 2023
FDA ORPHAN DRUG 31988
Created by admin on Sat Dec 16 00:25:58 GMT 2023 , Edited by admin on Sat Dec 16 00:25:58 GMT 2023
NCI_THESAURUS C76358
Created by admin on Sat Dec 16 00:25:58 GMT 2023 , Edited by admin on Sat Dec 16 00:25:58 GMT 2023
Code System Code Type Description
USAN
AA-87
Created by admin on Sat Dec 16 00:25:58 GMT 2023 , Edited by admin on Sat Dec 16 00:25:58 GMT 2023
PRIMARY
PUBCHEM
91820622
Created by admin on Sat Dec 16 00:25:58 GMT 2023 , Edited by admin on Sat Dec 16 00:25:58 GMT 2023
PRIMARY
RXCUI
58932
Created by admin on Sat Dec 16 00:25:58 GMT 2023 , Edited by admin on Sat Dec 16 00:25:58 GMT 2023
PRIMARY RxNorm
ChEMBL
CHEMBL1201490
Created by admin on Sat Dec 16 00:25:58 GMT 2023 , Edited by admin on Sat Dec 16 00:25:58 GMT 2023
PRIMARY
DRUG BANK
DBSALT001439
Created by admin on Sat Dec 16 00:25:58 GMT 2023 , Edited by admin on Sat Dec 16 00:25:58 GMT 2023
PRIMARY
CAS
114466-38-5
Created by admin on Sat Dec 16 00:25:58 GMT 2023 , Edited by admin on Sat Dec 16 00:25:58 GMT 2023
PRIMARY
FDA UNII
00IBG87IQW
Created by admin on Sat Dec 16 00:25:58 GMT 2023 , Edited by admin on Sat Dec 16 00:25:58 GMT 2023
PRIMARY
EVMPD
SUB04370MIG
Created by admin on Sat Dec 16 00:25:58 GMT 2023 , Edited by admin on Sat Dec 16 00:25:58 GMT 2023
PRIMARY
NCI_THESAURUS
C47715
Created by admin on Sat Dec 16 00:25:58 GMT 2023 , Edited by admin on Sat Dec 16 00:25:58 GMT 2023
PRIMARY