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Details

Stereochemistry ABSOLUTE
Molecular Formula C6H10O7
Molecular Weight 194.1394
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of .BETA.-D-GLUCOURONIC ACID

SMILES

O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O

InChI

InChIKey=AEMOLEFTQBMNLQ-QIUUJYRFSA-N
InChI=1S/C6H10O7/c7-1-2(8)4(5(10)11)13-6(12)3(1)9/h1-4,6-9,12H,(H,10,11)/t1-,2-,3+,4-,6+/m0/s1

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Localization of cell wall polysaccharides in nonarticulated laticifers of Asclepias speciosa Torr.
2001
Directly coupled HPLC-NMR and HPLC-MS approaches for the rapid characterisation of drug metabolites in urine: application to the human metabolism of naproxen.
2001 Feb
Polymorphisms of UDP-glucuronosyltransferase and pharmacokinetics of irinotecan.
2002 Feb
Transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II cell monolayer expressing both human organic anion-transporting polypeptide (OATP2/SLC21A6) and Multidrug resistance-associated protein 2 (MRP2/ABCC2).
2002 Feb 22
Structural features of an arabinogalactan gum exudates from Spondias dulsis (Anacardiaceae).
2003 Mar 28
The detection of piroxicam, tenoxicam and their metabolites in equine urine by electrospray ionisation ion trap mass spectrometry.
2004
Biopharmaceutics of beta-cyclodextrin derivative-based formulations of acitretin in Sprague-Dawley rats.
2004 Apr
Structural studies of the capsular polysaccharide of a non-neoformans Cryptococcus species identified as C. laurentii, which was reclassified as Cryptococcus flavescens, from a patient with AIDS.
2004 Feb 25
Venous and arterial thrombosis in rat models: dissociation of the antithrombotic effects of glycosaminoglycans.
2004 Jan
Hapten-directed targeting to single-chain antibody receptors.
2004 May
Pharmacokinetics, metabolism and excretion of intravenous [l4C]-palonosetron in healthy human volunteers.
2004 Nov
Detection of stanozolol and its metabolites in equine urine by liquid chromatography-electrospray ionization ion trap mass spectrometry.
2004 Nov 5
Estradiol 3-glucuronide is transported by the multidrug resistance-associated protein 2 but does not activate the allosteric site bound by estradiol 17-glucuronide.
2004 Oct
Density functional study of the conformational space of 4C1 D-glucuronic acid.
2005 Feb 10
Distribution of small proteoglycans and glycosaminoglycans in humerus-related articular cartilage of chickens.
2005 Mar
A phase I clinical and pharmacokinetic study of capecitabine (Xeloda) and irinotecan combination therapy (XELIRI) in patients with metastatic gastrointestinal tumours.
2005 Mar 14
Optimization of an enzymatic method for the determination of lysosomal N-acetyl-beta-D-hexosaminidase and beta-glucuronidase in synovial fluid.
2006
Increase in hyaluronic acid production by Streptococcus equi subsp. zooepidemicus strain deficient in beta-glucuronidase in laboratory conditions.
2006 Jul
Cytokines and proteoglycans: an introductory overview.
2006 Jun
Development and properties of beta-glucuronide linkers for monoclonal antibody-drug conjugates.
2006 May-Jun
Evaluation of novel fluorogenic substrates for the detection of glycosidases in Escherichia coli and enterococci.
2006 Nov
Glycosidation-anomerisation reactions of 6,1-anhydroglucopyranuronic acid and anomerisation of beta-D-glucopyranosiduronic acids promoted by SnCl(4).
2007
Minor groove binder antibody conjugates employing a water soluble beta-glucuronide linker.
2007 Apr 15
Predominant contribution of UDP-glucuronosyltransferase 2B7 in the glucuronidation of racemic flurbiprofen in the human liver.
2007 Jul
[Identification of metabolites of environmental hormone butylbenzyl phthalate in mice urine by liquid chromatography/ion trap mass spectrometry].
2007 Mar
Selectin blocking activity of a fucosylated chondroitin sulfate glycosaminoglycan from sea cucumber. Effect on tumor metastasis and neutrophil recruitment.
2007 May 18
Effects of monoglycerides on rhodamine 123 accumulation, estradiol 17 beta-D-glucuronide bidirectional transport and MRP2 protein expression within Caco-2 cells.
2008
Oral absorption enhancement of dipeptide L-Glu-L-Trp-OH by lipid and glycosyl conjugation.
2008
Kinetic and J-resolved statistical total correlation NMR spectroscopy approaches to structural information recovery in complex reacting mixtures: application to acyl glucuronide intramolecular transacylation reactions.
2008 Jul 1
Vibrational analysis of N-acetyl-alpha-D-glucosamine and beta-D-glucuronic acid.
2008 May 8
The structure of Cryptococcus neoformans galactoxylomannan contains beta-D-glucuronic acid.
2009 May 12
Application of a key events dose-response analysis to nutrients: a case study with vitamin A (retinol).
2009 Sep
Conformational properties of the disaccharide building units of hyaluronan.
2009 Sep 8
NMR spectroscopy evaluation of direct relationship between soils and molecular composition of red wines from Aglianico grapes.
2010 Jul 19
Understanding chemotherapy treatment pathways of advanced colorectal cancer patients to inform an economic evaluation in the United Kingdom.
2010 Jul 27
Regio- and stereospecific synthesis of mono-beta-d-glucuronic acid derivatives of combretastatin A-1.
2010 Jun 25
Biotransformation of fluorobiphenyl by Cunninghamella elegans.
2010 Mar
Conformational free energies of methyl-alpha-L-iduronic and methyl-beta-D-glucuronic acids in water.
2010 Mar 14
Patents
Name Type Language
.BETA.-D-GLUCOURONIC ACID
Common Name English
GLUCOPYRANURONIC ACID, .BETA.-D-
Common Name English
.BETA.-D-GLUCOPYRANOSYLURONIC ACID
Common Name English
BETA-GLUCOURONIC ACID
Common Name English
GLUCURONIC ACID, .BETA.-D
Common Name English
BETA-D-GLUCOURONIC ACID
Common Name English
(2S,3S,4S,5R,6R)-3,4,5,6-TETRAHYDROXYOXANE-2-CARBOXYLIC ACID
Systematic Name English
Code System Code Type Description
DAILYMED
00A9JB14O6
Created by admin on Sat Dec 16 10:00:48 GMT 2023 , Edited by admin on Sat Dec 16 10:00:48 GMT 2023
PRIMARY
PUBCHEM
441478
Created by admin on Sat Dec 16 10:00:48 GMT 2023 , Edited by admin on Sat Dec 16 10:00:48 GMT 2023
PRIMARY
CAS
23018-83-9
Created by admin on Sat Dec 16 10:00:48 GMT 2023 , Edited by admin on Sat Dec 16 10:00:48 GMT 2023
PRIMARY
EPA CompTox
DTXSID801336828
Created by admin on Sat Dec 16 10:00:48 GMT 2023 , Edited by admin on Sat Dec 16 10:00:48 GMT 2023
PRIMARY
DRUG BANK
DB03156
Created by admin on Sat Dec 16 10:00:48 GMT 2023 , Edited by admin on Sat Dec 16 10:00:48 GMT 2023
PRIMARY
RXCUI
2569975
Created by admin on Sat Dec 16 10:00:48 GMT 2023 , Edited by admin on Sat Dec 16 10:00:48 GMT 2023
PRIMARY
FDA UNII
00A9JB14O6
Created by admin on Sat Dec 16 10:00:48 GMT 2023 , Edited by admin on Sat Dec 16 10:00:48 GMT 2023
PRIMARY