DEXINDOPROFEN

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C17H15NO3
Molecular Weight	281.3059
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C[C@H](C(O)=O)C1=CC=C(C=C1)N2CC3=C(C=CC=C3)C2=O

InChI

InChIKey=RJMIEHBSYVWVIN-NSHDSACASA-N

InChI=1S/C17H15NO3/c1-11(17(20)21)12-6-8-14(9-7-12)18-10-13-4-2-3-5-15(13)16(18)19/h2-9,11H,10H2,1H3,(H,20,21)/t11-/m0/s1

HIDE SMILES / InChI

Description
Sources: https://www.healthdictionary.info/Dexindoprofen.htm | Aronson, J.K. (2010) Side Effects of Drugs Annual, page 230, retrieved from: https://books.google.ru/books?id=mA1COEQfbs0C | Challener, C.A. (2017) Chiral Drugs, retrieved from: https://books.google.ru/books?id=ZQA7DwAAQBAJ

Dexindoprofen is a non-steroidal drug that has analgesic and anti-inflammatory properties. Dexindoprofen is the dextrorotatory stereo-isomer of indoprofen, to which it has a similar adverse effect pattern. Gastrointestinal and nervous system effects and skin reactions are the most frequent. Following reports of severe gastrointestinal bleeding and carcinogenicity in animals indoprofen was withdrawn from the market worldwide.

Approval Year

Patents

Name

Type

Language

DEXINDOPROFEN

Official Name

English

(.ALPHA.S)-4-(1,3-DIHYDRO-1-OXO-2H-ISOINDOL-2-YL)-.ALPHA.-METHYLBENZENEACETIC ACID

Common Name

English

D-INDOPROFEN

Common Name

English

BENZENEACETIC ACID, 4-(1,3-DIHYDRO-1-OXO-2H-ISOINDOL-2-YL)-.ALPHA.-METHYL-, (S)-

Common Name

English

BENZENEACETIC ACID, 4-(1,3-DIHYDRO-1-OXO-2H-ISOINDOL-2-YL)-.ALPHA.-METHYL-, (.ALPHA.S)-

Systematic Name

English

(+)-INDOPROFEN

Common Name

English

S(+)-INDOPROFEN

Common Name

English

(+)-(S)-P-(1-OXO-2-ISOINDOLINYL)HYDRATROPIC ACID

Common Name

English

INDOPROFEN (+)-FORM [MI]

Common Name

English

NEDIUS

Brand Name

English

dexindoprofen [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C257