U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C25H30N2O4
Molecular Weight 422.5167
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of IPTACOPAN

SMILES

CCO[C@H]1CCN(CC2=C(OC)C=C(C)C3=C2C=CN3)[C@@H](C1)C4=CC=C(C=C4)C(O)=O

InChI

InChIKey=RENRQMCACQEWFC-UGKGYDQZSA-N
InChI=1S/C25H30N2O4/c1-4-31-19-10-12-27(22(14-19)17-5-7-18(8-6-17)25(28)29)15-21-20-9-11-26-24(20)16(2)13-23(21)30-3/h5-9,11,13,19,22,26H,4,10,12,14-15H2,1-3H3,(H,28,29)/t19-,22-/m0/s1

HIDE SMILES / InChI

Molecular Formula C25H30N2O4
Molecular Weight 422.5167
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Substance Class Chemical
Created
by admin
on Sat Dec 16 14:35:26 GMT 2023
Edited
by admin
on Sat Dec 16 14:35:26 GMT 2023
Record UNII
8E05T07Z6W
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
IPTACOPAN
INN   USAN  
Official Name English
iptacopan [INN]
Common Name English
IPTACOPAN [USAN]
Common Name English
LNP-023
Code English
NVP-LNP023
Code English
LNP023
Code English
NVP-LNP023-NX
Code English
Iptacopan [WHO-DD]
Common Name English
BENZOIC ACID, 4-((2S,4S)-4-ETHOXY-1-((5-METHOXY-7-METHYL-1H-INDOL-4-YL)METHYL)-2-PIPERIDINYL)-
Systematic Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 692819
Created by admin on Sat Dec 16 14:35:27 GMT 2023 , Edited by admin on Sat Dec 16 14:35:27 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C156691
Created by admin on Sat Dec 16 14:35:27 GMT 2023 , Edited by admin on Sat Dec 16 14:35:27 GMT 2023
PRIMARY
PUBCHEM
90467622
Created by admin on Sat Dec 16 14:35:27 GMT 2023 , Edited by admin on Sat Dec 16 14:35:27 GMT 2023
PRIMARY
WIKIPEDIA
Iptacopan
Created by admin on Sat Dec 16 14:35:27 GMT 2023 , Edited by admin on Sat Dec 16 14:35:27 GMT 2023
PRIMARY
SMS_ID
300000023892
Created by admin on Sat Dec 16 14:35:27 GMT 2023 , Edited by admin on Sat Dec 16 14:35:27 GMT 2023
PRIMARY
INN
11259
Created by admin on Sat Dec 16 14:35:27 GMT 2023 , Edited by admin on Sat Dec 16 14:35:27 GMT 2023
PRIMARY
FDA UNII
8E05T07Z6W
Created by admin on Sat Dec 16 14:35:27 GMT 2023 , Edited by admin on Sat Dec 16 14:35:27 GMT 2023
PRIMARY
CAS
1644670-37-0
Created by admin on Sat Dec 16 14:35:27 GMT 2023 , Edited by admin on Sat Dec 16 14:35:27 GMT 2023
PRIMARY
USAN
JK-156
Created by admin on Sat Dec 16 14:35:27 GMT 2023 , Edited by admin on Sat Dec 16 14:35:27 GMT 2023
PRIMARY
Related Record Type Details
SALT/SOLVATE -> PARENT
TARGET -> INHIBITOR
Kd
SALT/SOLVATE -> PARENT
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ACTIVE MOIETY