U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 5801 - 5810 of 12702 results

Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)


Isoxicam is a nonsteroidal anti-inflammatory drug with long half-life. The major oxidative excretion product of isoxicam is the hydroxymethlyisoxazole metabolite, minor metabolites are open-ring sulfonamide and N-methylsaccharin. Isoxicam Is effective and well tolerated in all the major rheumatic diseases.
Status:
Possibly Marketed Outside US
Source:
Zevtera by Avir Pharma Inc [Canada]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Ceftobiprole is a fifth-generation cephalosporin antibiotic. It was discovered by Basilea Pharmaceutica and was developed by Johnson & Johnson Pharmaceutical Research and Development. The drug is demonstrates activity against clinically important gram-positive pathogens, including methicillin-resistant Staphylococcus aureus, penicilliin-resistant Staphylococcus pneumoniae, and Enterococcus faecalis. The drug also has demonstrated activity against gram-negative bacteria including Citrobacter spp., Escherichia coli, Enterobacter spp., Klebsiella spp., Serratia marcescens, and Pseudomonas aeruginosa. The drug has gained regulatory authorization from European states for the treatment of hospital-acquired pneumonia (HAP, excluding ventilator-associated pneumonia, VAP) and community-acquired pneumonia (CAP).
Zinterol (MJ-9184-1) is an beta-adregenrgic agonist demostrated activity toward beta1-3 receptors. Oral zinterol caused a fast-appearing and long-lasting bronchodilator effect in patients with with stable chronic obstructive lung disease, however it seems development of zinterol was discontitued.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ABSOLUTE)

Zofenoprilat arginine is an Angiotensin-converting enzyme inhibitor. Its proline nucleus has phenylmercapto and mercaptomethylpropionyl additions, and is combined with a molecule of arginine in salt form. It was developed as antihypertensive agent.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)

Zomebazam is is a pyrazolodiazepinone derivative drug. It is anxiolytic, nootropic drug. Zomebazam is the mother compound of razobazam. It is structurally related to zometapine.
Status:
Possibly Marketed Outside US
Source:
Zylofuramine by ZYF Pharm Chemical
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Zylofuramine is a psychomotor stimulant. It intended for use as an appetite suppressant and for the treatment of senile dementia in the elderly, but there is little information about it and it does not appear to have ever been marketed.
Status:
Possibly Marketed Outside US
Source:
Japan:Tolycaine Hydrochloride
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Tolycaine hydrochloride is an amide local anaesthetic included in some preparations to reduce the pain of injection. It can be used for dental injection.
Status:
Possibly Marketed Outside US
Source:
Duratocin by Ferring Pharmaceuticals [Canada]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Carbetocin is a synthetic analogue of human peptide hormone, oxytocin. Like oxytocin, it stimulate oxytocin receptors and is used to facilitate childbirth. The drug is being marketed in Europe under the name Pabal for the prevention of uterine atony following delivery of the infant by Caesarean section. If untreated by carbetocin, uterine atony may lead to postpartum haemorrhage.
Status:
Possibly Marketed Outside US
Source:
SPECTAMINE by Medi-Physics
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Conditions:

Iofetamine is a diagnostic compound that was used for brain-imaging. Iofetamine may cause different adverse reactions such as increase in systolic blood pressure by about 10 mm Hg, dizziness, hearing loss and allergy.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)


Prenoxdiazine under the brand name Libexin is used as an antitussive agent. It was shown, that the use of this drug for pregnant women with an unproductive cough could be beneficial.

Showing 5801 - 5810 of 12702 results