U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 34151 - 34160 of 34955 results

Status:
Possibly Marketed Outside US
Source:
Veraflox by Bayer
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)



Pradofloxacin (trade name Veraflox) is a 3rd generation enhanced spectrum veterinary antibiotic of the fluoroquinolone class. It was developed by Bayer HealthCare AG, Animal Health GmbH, and received approval from the European Commission in April 2011 for prescription-only use in veterinary medicine for the treatment of bacterial infections in dogs and cats. The primary mode of action of fluoroquinolones involves interaction with enzymes essential for major DNA functions such as replication, transcription, and recombination. The primary targets for Pradofloxacin are the bacterial DNA gyrase and topoisomerase IV enzymes. Reversible association between Pradofloxacin and DNA gyrase or DNA topoisomerase IV in the target bacteria results in inhibition of these enzymes and rapid death of the bacterial cell. The rapidity and extent of bacterial killing are directly proportional to the drug concentration.
Status:
Possibly Marketed Outside US
Source:
NCT03023514: Phase 4 Interventional Completed Women Infertility
(2015)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

THIOCTIC ACID, also known as alpha-lipoic acid, is a vitamin-like antioxidant that acts as a free-radical scavenger. It exists in two enantiomeric forms, R and S, being the R isoform an essential cofactor of four mitochondrial enzyme complexes. THIOCTIC ACID is available as an over-the-counter nutritional supplement and has been used nutritionally and clinically since the 1950s for various diseases and conditions.
Status:
Possibly Marketed Outside US
Source:
NCT03023514: Phase 4 Interventional Completed Women Infertility
(2015)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

THIOCTIC ACID, also known as alpha-lipoic acid, is a vitamin-like antioxidant that acts as a free-radical scavenger. It exists in two enantiomeric forms, R and S, being the R isoform an essential cofactor of four mitochondrial enzyme complexes. THIOCTIC ACID is available as an over-the-counter nutritional supplement and has been used nutritionally and clinically since the 1950s for various diseases and conditions.
Status:
Possibly Marketed Outside US
Source:
NCT03023514: Phase 4 Interventional Completed Women Infertility
(2015)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

THIOCTIC ACID, also known as alpha-lipoic acid, is a vitamin-like antioxidant that acts as a free-radical scavenger. It exists in two enantiomeric forms, R and S, being the R isoform an essential cofactor of four mitochondrial enzyme complexes. THIOCTIC ACID is available as an over-the-counter nutritional supplement and has been used nutritionally and clinically since the 1950s for various diseases and conditions.
Status:
Possibly Marketed Outside US
Source:
NCT03023514: Phase 4 Interventional Completed Women Infertility
(2015)
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

THIOCTIC ACID, also known as alpha-lipoic acid, is a vitamin-like antioxidant that acts as a free-radical scavenger. It exists in two enantiomeric forms, R and S, being the R isoform an essential cofactor of four mitochondrial enzyme complexes. THIOCTIC ACID is available as an over-the-counter nutritional supplement and has been used nutritionally and clinically since the 1950s for various diseases and conditions.
Status:
Possibly Marketed Outside US
Source:
Tricare Prenatal Compleat by Medecor Pharma, Llc
Source URL:
First approved in 2013
Source:
TRICARE PRENATAL COMPLEATDHA ONE by Medecor Pharma, LLC
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

11(E)-Eicosenoic acid is a very long-chain ω-9 fatty acid that is a trans monounsaturated isomer of arachidic acid. 11(E)-Eicosenoic acid is one of several monounsaturated 20-carbon fatty acids, and is used to study phospholipid membranes. The combined C20:1 isomers constitute 70% of the total fatty acid pool in jojoba seed oil isolated from plants in the Arizona desert. 11(E)-Eicosenoic acid has been shown to inhibit glycerophosphate acyltransferase, cholinephosphotransferase and ethanolaminephosphotransferase in V79-R cells. 11(E)-Eicosenoic acid lacks the cis-double bond and has virtually no effect on telomerase activity (unlike cis-Unsaturated C20 fatty acids, which demonstrate strong telomerase inhibition and have been studied as a promising cancer therapeutic target).

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Ethyl sulfate is a metabolite of ethanol and a biomarker of recent alcohol consumption that provide objective measures of abstinence.

Showing 34151 - 34160 of 34955 results