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Restrict the search for
pantothenic acid
to a specific field?
Class (Stereo):
CHEMICAL (MIXED)
Nileprost is a prostacyclin analogue stabilized by introduction of the cyano group at its 5-position. Nileprost is a mixed type PGI2/PGE2 agonist. The development of the prostaglandin analogue nileprost [ZK 34798] for use in peptic ulcers has been discontinued at phase II by Schering AG in Germany.
Status:
Investigational
Source:
INN:monalazone disodium [INN]
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Monalazone is a sulfonylbenzoic acid derivative used as vaginal disinfectant or antiseptic and spermicidal contraceptive.
Class (Stereo):
CHEMICAL (RACEMIC)
Furaprofen (also known as R-803), a nonsteroidal drug possesses anti-inflammatory properties. This drug was studied for the treatment of rheumatoid arthritis. However, information about the further development of this drug is not available.
Status:
Investigational
Source:
NCT01063920: Phase 2/Phase 3 Interventional Completed Osteoarthritis
(2010)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Naproxen etemesil is a lipophilic, non-acidic, inactive prodrug of the non-steroidal anti-inflammatory drug (NSAID) naproxen that is hydrolysed to pharmacologically active naproxen once absorbed. Naproxen etemesil was in development with Logical Therapeutics for the treatment of osteoarthritis. However, no recent development has been reported. It is also in phase I clinical trials for the treatment of inflammation and arthritis.The compound was originally developed by Medinox, licensed to Logical Therapeutics in 2006 for partial rights.
Class (Stereo):
CHEMICAL (ACHIRAL)
Phetharbital (Pyrictal), a barbiturate with virtually no hypnotic side effects, was originally introduced for the management of epilepsy and has since been shown to have powerful hepatic enzyme-inducing properties. In preliminary clinical studies, phetharbital was found to be effective against febrile seizures, minor myoclonic seizures and in petit mal. Phetharbital is relatively ineffective in the control of the tonic extensor seizure pattern and would not be expected to modify grand mal tonic seizures. Chronic administration of phetharbital causes an increased excretion of 6 beta-hydroxycortisol in human urine. This increase in 6 beta-hydroxycortisol excretion is not accompanied by an increase in the 17-hydroxycorticosteroids levels in urine, indicating that an increased adrenal output of cortisol is not responsible for the increased urinary levels of 6 beta hydroxycortisol. Phetharbital was also effective in the rare severe unconjugated hyperbilirubinemia of the Crigler-Najjar syndrome.
Class (Stereo):
CHEMICAL (RACEMIC)
Vincofos is a broad-spectrum canine anthelmintic. All or nearly all of the ascarids, hookworms, whipworms, and the tapeworm, Taenia pisiformis, were expelled following therapy with vincofos. The tapeworm, Dipylidium caninum, was also effectively removed by the vincofos treatment, but it appeared that a slightly greater dosage would be required to obtain maximum anthelmintic effect.
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Investigational
Source:
NCT00404248: Phase 1/Phase 2 Interventional Completed Brain and Central Nervous System Tumors
(2007)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Temperocol is an investigative anti-cancer drug that inhibits the expression of survivin and CDK-1; discovered at Johns Hopkins University and under development by Erimos Pharmaceuticals. It has been tested in phase I/II clinical trials for Leukemia, and several forms of neoplasms including gliomas. Results of these clinical trials have shown promise, however treatment regimes produce several toxic side effects that need to be balanced against efficacy. Temperocol is a fully methylated derivative of the natural product Nordihydroguaiaretic acid.
Status:
Investigational
Source:
NCT00597662: Phase 1 Interventional Completed Adhesions
(2008)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
Picotrin is the keratolytic agent. It was used for the treatment of acne.
