U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C24H29N5O3
Molecular Weight 435.5188
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of VALSARTAN

SMILES

CCCCC(=O)N(CC1=CC=C(C=C1)C2=C(C=CC=C2)C3=NN=NN3)[C@@H](C(C)C)C(O)=O

InChI

InChIKey=ACWBQPMHZXGDFX-QFIPXVFZSA-N
InChI=1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m0/s1

HIDE SMILES / InChI

Description

Valsartan (DIOVAN®) is a tetrazole derivative, and specific angiotensin II type 1 (AT1) receptor blocker that is indicated for the treatment of hypertension, to lower blood pressure. Angiotensin II is formed from angiotensin I in a reaction catalyzed by angiotensin-converting enzyme. Angiotensin II is the principal pressor agent of the renin-angiotensin system, with effects that include vasoconstriction, stimulation of synthesis and release of aldosterone, cardiac stimulation, and renal reabsorption of sodium. Valsartan (DIOVAN®) blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland. Its action is therefore independent of the pathways for angiotensin II synthesis.

CNS Activity

Curator's Comment: LBQ657 (an LCZ696 metabolite) achieves CSF concentrations sufficient to inhibit neprilysin, but LCZ696 did not cause changes in CSF levels of aggregable Abeta isoforms (1-42 and 1-40) compared with placebo

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
ENTRESTO

Approved Use

ENTRESTO is a combination of sacubitril, a neprilysin inhibitor, and valsartan, an angiotensin II receptor blocker, indicated to reduce the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure (NYHA Class II-IV) and reduced ejection fraction. ENTRESTO is usually administered in conjunction with other heart failure therapies, in place of an ACE inhibitor or other ARB.

Launch Date

2015
Primary
DIOVAN

Approved Use

Diovan is an angiotensin II receptor blocker (ARB) indicated for: Treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions (1.1) Treatment of heart failure (NYHA class II-IV); Diovan significantly reduced hospitalization for heart failure (1.2) Reduction of cardiovascular mortality in clinically stable patients with left ventricular failure or left ventricular dysfunction following myocardial infarction (1.3)

Launch Date

2011
Primary
DIOVAN

Approved Use

Diovan is an angiotensin II receptor blocker (ARB) indicated for: Treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions (1.1) Treatment of heart failure (NYHA class II-IV); Diovan significantly reduced hospitalization for heart failure (1.2) Reduction of cardiovascular mortality in clinically stable patients with left ventricular failure or left ventricular dysfunction following myocardial infarction (1.3)

Launch Date

2011
Palliative
DIOVAN

Approved Use

Diovan is an angiotensin II receptor blocker (ARB) indicated for: Treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions (1.1) Treatment of heart failure (NYHA class II-IV); Diovan significantly reduced hospitalization for heart failure (1.2) Reduction of cardiovascular mortality in clinically stable patients with left ventricular failure or left ventricular dysfunction following myocardial infarction (1.3)

Launch Date

2011
Cmax

Cmax

ValueDoseCo-administeredAnalytePopulation
2808 ng/mL
80 mg single, oral
dose: 80 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
VALSARTAN plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: FEMALE / MALE
food status: FASTED
5756 ng/mL
80 mg single, oral
dose: 80 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
VALSARTAN plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: FEMALE / MALE
food status: FASTED
2.141 μg/mL
160 mg single, oral
dose: 160 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
VALSARTAN plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: MALE
food status: UNKNOWN
AUC

AUC

ValueDoseCo-administeredAnalytePopulation
20650 ng × h/mL
80 mg single, oral
dose: 80 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
VALSARTAN plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: FEMALE / MALE
food status: FASTED
34310 ng × h/mL
80 mg single, oral
dose: 80 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
VALSARTAN plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: FEMALE / MALE
food status: FASTED
22.56 μg × h/mL
160 mg single, oral
dose: 160 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
VALSARTAN plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: MALE
food status: UNKNOWN
T1/2

T1/2

ValueDoseCo-administeredAnalytePopulation
8.45 h
80 mg single, oral
dose: 80 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
VALSARTAN plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: FEMALE / MALE
food status: FASTED
8 h
80 mg single, oral
dose: 80 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
VALSARTAN plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: FEMALE / MALE
food status: FASTED
9.55 h
160 mg single, oral
dose: 160 mg
route of administration: Oral
experiment type: SINGLE
co-administered:
VALSARTAN plasma
Homo sapiens
population: HEALTHY
age: ADULT
sex: MALE
food status: UNKNOWN
Doses

Doses

DosePopulationAdverse events​
2.24 mg single, oral
Overdose
Dose: 2.24 mg
Route: oral
Route: single
Dose: 2.24 mg
Sources:
unknown, 25 years
n = 1
Health Status: unknown
Age Group: 25 years
Sex: F
Population Size: 1
Sources:
Other AEs: Muscle cramps...
Other AEs:
Muscle cramps (1 patient)
Sources:
640 mg 1 times / day steady, oral
Highest studied dose
Dose: 640 mg, 1 times / day
Route: oral
Route: steady
Dose: 640 mg, 1 times / day
Sources:
unhealthy, 57.5 years
n = 131
Health Status: unhealthy
Age Group: 57.5 years
Sex: M+F
Population Size: 131
Sources:
Disc. AE: Hyperkalemia...
Other AEs: Dizziness, Headache...
AEs leading to
discontinuation/dose reduction:
Hyperkalemia (1 patient)
Other AEs:
Dizziness (8.3%)
Headache (9.2%)
Back pain (5.8%)
Upper respiratory tract infection (5.8%)
Nasopharyngitis (5%)
Diarrhea (5%)
Hypoglycemia (5%)
Peripheral edema (4.2%)
Nausea (4.2%)
Sources:
320 mg 1 times / day steady, oral
Recommended
Dose: 320 mg, 1 times / day
Route: oral
Route: steady
Dose: 320 mg, 1 times / day
Sources:
pregnant
Disc. AE: Disorder fetal...
320 mg 1 times / day steady, oral
Recommended
Dose: 320 mg, 1 times / day
Route: oral
Route: steady
Dose: 320 mg, 1 times / day
Sources:
unhealthy
n = 2316
Health Status: unhealthy
Condition: hypertension
Population Size: 2316
Sources:
Disc. AE: Headache, Dizziness...
AEs leading to
discontinuation/dose reduction:
Headache (2.3%)
Dizziness (2.3%)
Sources:
320 mg 1 times / day steady, oral
Recommended
Dose: 320 mg, 1 times / day
Route: oral
Route: steady
Dose: 320 mg, 1 times / day
Sources:
unhealthy
n = 2506
Health Status: unhealthy
Condition: Heart Failure
Population Size: 2506
Sources:
Disc. AE: Creatinine increased, Potassium increased...
AEs leading to
discontinuation/dose reduction:
Creatinine increased (0.5%)
Potassium increased (0.5%)
Sources:
AEs

AEs

AESignificanceDosePopulation
Muscle cramps 1 patient
2.24 mg single, oral
Overdose
Dose: 2.24 mg
Route: oral
Route: single
Dose: 2.24 mg
Sources:
unknown, 25 years
n = 1
Health Status: unknown
Age Group: 25 years
Sex: F
Population Size: 1
Sources:
Hyperkalemia 1 patient
Disc. AE
640 mg 1 times / day steady, oral
Highest studied dose
Dose: 640 mg, 1 times / day
Route: oral
Route: steady
Dose: 640 mg, 1 times / day
Sources:
unhealthy, 57.5 years
n = 131
Health Status: unhealthy
Age Group: 57.5 years
Sex: M+F
Population Size: 131
Sources:
Nausea 4.2%
640 mg 1 times / day steady, oral
Highest studied dose
Dose: 640 mg, 1 times / day
Route: oral
Route: steady
Dose: 640 mg, 1 times / day
Sources:
unhealthy, 57.5 years
n = 131
Health Status: unhealthy
Age Group: 57.5 years
Sex: M+F
Population Size: 131
Sources:
Peripheral edema 4.2%
640 mg 1 times / day steady, oral
Highest studied dose
Dose: 640 mg, 1 times / day
Route: oral
Route: steady
Dose: 640 mg, 1 times / day
Sources:
unhealthy, 57.5 years
n = 131
Health Status: unhealthy
Age Group: 57.5 years
Sex: M+F
Population Size: 131
Sources:
Diarrhea 5%
640 mg 1 times / day steady, oral
Highest studied dose
Dose: 640 mg, 1 times / day
Route: oral
Route: steady
Dose: 640 mg, 1 times / day
Sources:
unhealthy, 57.5 years
n = 131
Health Status: unhealthy
Age Group: 57.5 years
Sex: M+F
Population Size: 131
Sources:
Hypoglycemia 5%
640 mg 1 times / day steady, oral
Highest studied dose
Dose: 640 mg, 1 times / day
Route: oral
Route: steady
Dose: 640 mg, 1 times / day
Sources:
unhealthy, 57.5 years
n = 131
Health Status: unhealthy
Age Group: 57.5 years
Sex: M+F
Population Size: 131
Sources:
Nasopharyngitis 5%
640 mg 1 times / day steady, oral
Highest studied dose
Dose: 640 mg, 1 times / day
Route: oral
Route: steady
Dose: 640 mg, 1 times / day
Sources:
unhealthy, 57.5 years
n = 131
Health Status: unhealthy
Age Group: 57.5 years
Sex: M+F
Population Size: 131
Sources:
Back pain 5.8%
640 mg 1 times / day steady, oral
Highest studied dose
Dose: 640 mg, 1 times / day
Route: oral
Route: steady
Dose: 640 mg, 1 times / day
Sources:
unhealthy, 57.5 years
n = 131
Health Status: unhealthy
Age Group: 57.5 years
Sex: M+F
Population Size: 131
Sources:
Upper respiratory tract infection 5.8%
640 mg 1 times / day steady, oral
Highest studied dose
Dose: 640 mg, 1 times / day
Route: oral
Route: steady
Dose: 640 mg, 1 times / day
Sources:
unhealthy, 57.5 years
n = 131
Health Status: unhealthy
Age Group: 57.5 years
Sex: M+F
Population Size: 131
Sources:
Dizziness 8.3%
640 mg 1 times / day steady, oral
Highest studied dose
Dose: 640 mg, 1 times / day
Route: oral
Route: steady
Dose: 640 mg, 1 times / day
Sources:
unhealthy, 57.5 years
n = 131
Health Status: unhealthy
Age Group: 57.5 years
Sex: M+F
Population Size: 131
Sources:
Headache 9.2%
640 mg 1 times / day steady, oral
Highest studied dose
Dose: 640 mg, 1 times / day
Route: oral
Route: steady
Dose: 640 mg, 1 times / day
Sources:
unhealthy, 57.5 years
n = 131
Health Status: unhealthy
Age Group: 57.5 years
Sex: M+F
Population Size: 131
Sources:
Disorder fetal Disc. AE
320 mg 1 times / day steady, oral
Recommended
Dose: 320 mg, 1 times / day
Route: oral
Route: steady
Dose: 320 mg, 1 times / day
Sources:
pregnant
Dizziness 2.3%
Disc. AE
320 mg 1 times / day steady, oral
Recommended
Dose: 320 mg, 1 times / day
Route: oral
Route: steady
Dose: 320 mg, 1 times / day
Sources:
unhealthy
n = 2316
Health Status: unhealthy
Condition: hypertension
Population Size: 2316
Sources:
Headache 2.3%
Disc. AE
320 mg 1 times / day steady, oral
Recommended
Dose: 320 mg, 1 times / day
Route: oral
Route: steady
Dose: 320 mg, 1 times / day
Sources:
unhealthy
n = 2316
Health Status: unhealthy
Condition: hypertension
Population Size: 2316
Sources:
Creatinine increased 0.5%
Disc. AE
320 mg 1 times / day steady, oral
Recommended
Dose: 320 mg, 1 times / day
Route: oral
Route: steady
Dose: 320 mg, 1 times / day
Sources:
unhealthy
n = 2506
Health Status: unhealthy
Condition: Heart Failure
Population Size: 2506
Sources:
Potassium increased 0.5%
Disc. AE
320 mg 1 times / day steady, oral
Recommended
Dose: 320 mg, 1 times / day
Route: oral
Route: steady
Dose: 320 mg, 1 times / day
Sources:
unhealthy
n = 2506
Health Status: unhealthy
Condition: Heart Failure
Population Size: 2506
Sources:
PubMed

PubMed

TitleDatePubMed
Efficacy and safety of LCZ696, a first-in-class angiotensin receptor neprilysin inhibitor, in Asian patients with hypertension: a randomized, double-blind, placebo-controlled study.
2014 Apr
LCZ696 : a new paradigm for the treatment of heart failure?
2015 Feb
Sacubitril/valsartan (LCZ696) for the treatment of heart failure.
2016
LCZ696 (Valsartan/Sacubitril)--A Possible New Treatment for Hypertension and Heart Failure.
2016 Jan
Patents

Sample Use Guides

The recommended starting dose of ENTRESTO, previously known as LCZ696, is 49/51 mg (sacubitril/valsartan) twice-daily. Double the dose of ENTRESTO after 2 to 4 weeks to the target maintenance dose of 97/103 mg (sacubitril/valsartan) twice-daily, as tolerated by the patient.
Route of Administration: Oral
In Vitro Use Guide
Sources: Von Lueder TG, Wang B, Kompa A, Huang L, Webb R, Jordan P, Krum H. ARNi, combined neprilysin and angiotensin receptor inhibition augments anti-fibrotic and anti-hypertrophic effects in vitro. Eur.Heart J. 2012;33:P5834.
Curator's Comment: ...
30 nM to 1 uM valsartan (LCZ696 component) in the presence of 10 uM LBQ657 (Sacubitril (LCZ696 component) metabolite) demonstrate anti-fibrotic and anti-hypertrophic effects on rat cardiac fibroblasts and cardiomyocytes, respectively, cultured with 100 nM angiotensin II
Name Type Language
VALSARTAN
EMA EPAR   EP   HSDB   INN   JAN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD  
INN   USAN  
Official Name English
VALSARTAN COMPONENT OF COPALIA
Brand Name English
COPALIA COMPONENT VALSARTAN
Brand Name English
VALSARTAN COMPONENT OF VALTURNA
Common Name English
L-VALINE, N-(1-OXOPENTYL)-N-((2'-(1H-TETRAZOL-5-YL)(1,1'-BIPHENYL)-4-YL)METHYL)-
Systematic Name English
VALSARTAN [VANDF]
Common Name English
VALSARTAN COMPONENT OF EXFORGE HCT
Common Name English
BYVALSON COMPONENT OF VALSARTAN
Common Name English
IMPRIDA-HCT COMPONENT VALSARTAN
Brand Name English
NSC-758927
Code English
CGP 48933
Code English
DIOVAN HCT COMPONENT VALSARTAN
Common Name English
VALSARTAN [EMA EPAR]
Common Name English
VALSARTAN [MI]
Common Name English
VALSARTAN [USP MONOGRAPH]
Common Name English
VALTURNA COMPONENT VALSARTAN
Brand Name English
VALSARTAN [USAN]
Common Name English
VALSARTAN [ORANGE BOOK]
Common Name English
VALSARTAN [EP IMPURITY]
Common Name English
VALSARTAN [MART.]
Common Name English
VALSARTAN COMPONENT OF IMMPRIDA
Brand Name English
VALSARTAN COMPONENT OF DIOVAN HCT
Common Name English
Valsartan [WHO-DD]
Common Name English
EXFORGE COMPONENT VALSARTAN
Brand Name English
VALSARTAN COMPONENT OF EXFORGE
Brand Name English
DIOVAN
Brand Name English
DAFIRO COMPONENT VALSARTAN
Brand Name English
VALSARTAN [HSDB]
Common Name English
VALSARTAN COMPONENT OF ENTRESTO
Brand Name English
AGSAV301 COMPONENT VALSARTAN
Common Name English
COPALIA-HCT COMPONENT VALSARTAN
Brand Name English
EXFORGE HCT COMPONENT VALSARTAN
Common Name English
VALSARTAN [USP-RS]
Common Name English
VALSARTAN [JAN]
Common Name English
VALSARTAN COMPONENT OF DAFIRO-HCT
Brand Name English
VALSARTAN COMPONENT OF COPALIA-HCT
Brand Name English
VALSARTAN COMPONENT OF BYVALSON
Common Name English
ENTRESTO COMPONENT VALSARTAN
Brand Name English
VALSARTAN [EP MONOGRAPH]
Common Name English
PREXXARTAN
Brand Name English
IMPRIDA COMPONENT VALSARTAN
Brand Name English
valsartan [INN]
Common Name English
VALSARTAN COMPONENT OF IMPRIDA-HCT
Brand Name English
DAFIRO-HCT COMPONENT VALSARTAN
Brand Name English
N-(P-(O-1H-TETRAZOL-5-YLPHENYL)BENZYL)-N-VALERYL-L-VALINE
Common Name English
CGP-48933
Code English
Classification Tree Code System Code
WHO-ATC C09CA03
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
EMA ASSESSMENT REPORTS IMPRADA-HCT (WITHDRAWN: HYPERTENSION)
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
WHO-ATC C10BX10
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
EMA ASSESSMENT REPORTS EXFORGE (AUTHORIZED: HYPERTENSION)
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
FDA ORPHAN DRUG 494115
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
WHO-VATC QC09CA03
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
NDF-RT N0000175561
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
WHO-ATC C09DX02
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
EMA ASSESSMENT REPORTS COPALIA (AUTHORIZED: HYPERTENSION)
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
WHO-ATC C09DX01
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
WHO-VATC QC09DA03
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
EMA ASSESSMENT REPORTS EXFORGE-HCT (AUTHORIZED: HYPERTENSION)
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
NCI_THESAURUS C66930
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
WHO-ATC C09DB08
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
EMA ASSESSMENT REPORTS DARFIRO-HCT (AUTHORIZED: HYPERTENSION)
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
LIVERTOX NBK547944
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
EMA ASSESSMENT REPORTS COPALIA-HCT (AUTHORIZED: HYPERTENSION)
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
WHO-ATC C09DA03
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
NDF-RT N0000000070
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
EMA ASSESSMENT REPORTS DAFIRO (AUTHORIZED: HYPERTENSION)
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
WHO-VATC QC09DX01
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
EMA ASSESSMENT REPORTS IMPRIDA (AUTHORIZED: HYPERTENSION)
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
WHO-ATC C09DX05
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
WHO-ATC C09DX04
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
WHO-VATC QC09DX02
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
WHO-ATC C09DB01
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
WHO-VATC QC09DB01
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
Code System Code Type Description
NSC
758927
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
PRIMARY
DAILYMED
80M03YXJ7I
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
PRIMARY
INN
7016
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
PRIMARY
RXCUI
69749
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
PRIMARY RxNorm
CAS
137862-53-4
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
PRIMARY
IUPHAR
3937
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
PRIMARY
ChEMBL
CHEMBL1069
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
PRIMARY
FDA UNII
80M03YXJ7I
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
PRIMARY
MESH
C081489
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
PRIMARY
WIKIPEDIA
VALSARTAN
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
PRIMARY
SMS_ID
100000088000
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
PRIMARY
RS_ITEM_NUM
1708762
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
PRIMARY
HSDB
7519
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
PRIMARY
EPA CompTox
DTXSID6023735
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
PRIMARY
DRUG BANK
DB00177
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
PRIMARY
NCI_THESAURUS
C47781
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
PRIMARY
LACTMED
Valsartan
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
PRIMARY
DRUG CENTRAL
2806
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
PRIMARY
CHEBI
9927
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
PRIMARY
USAN
HH-50
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
PRIMARY
MERCK INDEX
m11372
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
PRIMARY Merck Index
PUBCHEM
60846
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
PRIMARY
EVMPD
SUB00017MIG
Created by admin on Fri Dec 15 16:30:46 GMT 2023 , Edited by admin on Fri Dec 15 16:30:46 GMT 2023
PRIMARY